MYH7, c.2011C>T , is responsible for congenital scoliosis in a Chinese family [0.03%]
MYH7基因c.2011C＞T变异导致一名中国患者的先天性脊柱侧凸
Ping Wei,Fulong Xu,Caixia Xian et al.
Ping Wei et al.
Neuromuscular scoliosis can be caused by muscular or nervous system dysfunction resulting from genetic variants. Variation in MYH7 may cause hypertrophic or dilated cardiomyopathy, skeletal myopathies, or a combination of both; however, sco...
Comparison of two-dimensional and three-dimensional culture systems and their responses to chemotherapy in cells representing disease progression of high-grade serous ovarian cancer [0.03%]
高分级浆液性卵巢癌疾病进展的两种和三维培养系统及其对化疗的反应的比较
Naya El Mokbel,Alicia A Goyeneche,Rewati Prakash et al.
Naya El Mokbel et al.
High-grade serous cancer is the most common type of ovarian cancer and is usually diagnosed at advanced stages with high mortality due to recurrence and eventual resistance to standard platinum therapy. The aim of this study was to compare ...
Correlation of SNHG7 and BGL3 expression in patients with de novo acute myeloid leukemia; novel insights into lncRNA effect in PI3K signaling context in AML pathogenesis [0.03%]
SNHG7和BGL3在新诊断急性髓系白血病患者中的表达相关性；PI3K信号通路背景下长链非编码RNA对AML发病机制影响的新见解
Saeed Hassani,Parsa Rostami,Meshkat Pourtavakol et al.
Saeed Hassani et al.
Background: Acute myeloid leukemia (AML) has been identified as a top priority for discovering a reliable biomarker for treatment improvement and patient outcome prediction due to the heterogeneous nature of AML and the o...
Physical exercise improved the hematological effect of vitamin D in type 2 diabetes mellitus-induced nephrotoxicity in rats [0.03%]
运动改善维生素D在2型糖尿病诱导的肾毒性的血液系统效应
Halimat Amin Abdulrahim,Adeyemi Fatai Odetayo,Adeoye Tunwagun David et al.
Halimat Amin Abdulrahim et al.
Introduction: Globally, one of the major causes of renal dysfunction is diabetes mellitus (DM), and diabetic-induced nephrotoxicity has been linked with anemia. Presently, numerous antidiabetic drugs have been designed fo...
A comprehensive review of arginine kinase proteins: What we need to know? [0.03%]
精氨酸激酶蛋白综述：我们需要了解什么？
Brenda Martins Vasconcellos,Victor Guimarães Ribeiro,Naysha do Nascimento Campos et al.
Brenda Martins Vasconcellos et al.
The enzyme arginine kinase (AK), EC 2.7.3.3, catalyzes the reversible phosphorylation of arginine with adenosine triphosphate, forming phosphoarginine, which acts as an energy reservoir due to its high-energy phosphate content that can be r...
Molecular dynamics of three different α-helices in ribosomal protein L25 from Escherichia coli [0.03%]
大肠杆菌核糖体蛋白L25三种不同α-螺旋的动力学性质研究
Yuri Chirgadze,Ilya Likhachev,Nikolai Balabaev et al.
Yuri Chirgadze et al.
A true native protein state is realized in a water solution where proteins exhibit their dynamic properties important for the functioning. This is way we have analyzed the dynamics of α-helices inside ribosomal protein L25 from Escherichia...
Lutein and zeaxanthin reduce neuronal cell damage caused by lipid peroxidation [0.03%]
玉米黄质和叶黄素通过减少脂质过氧化诱导的神经元细胞损伤起保护作用
Satoshi Morita,Toshiaki Sueyasu,Hisanori Tokuda et al.
Satoshi Morita et al.
Oxidative stress and lipid peroxide levels in the brain increase with aging. The carotenoids lutein and zeaxanthin have potent antioxidant properties and the ability to improve cognitive function. However, their effects on neuronal damage v...
The dose-effect response of combined red and infrared photobiomodulation on insulin resistance in skeletal muscle cells [0.03%]
红光和近红外光生物模拟联合使用对骨骼肌细胞胰岛素抵抗剂量效应的影响研究
Gabriela Silva,Saulo Soares da Silva,Dimitrius Santiago Passos Simões Fróes Guimarães et al.
Gabriela Silva et al.
Obesity is a major public health problem and is a major contributor to the development of insulin resistance. In previous studies we observed that single-wavelength red or infrared photobiomodulation (PBM) improved insulin signaling in adip...
CEACAM1 increased the lymphangiogenesis through miR-423-5p and NF- kB in Non-Small Cell Lung Cancer [0.03%]
非小细胞肺癌中CEACAM1通过miR-423-5p和NF-κB促进淋巴管生成
Jie Yu,Wenke Cai,Tao Zhou et al.
Jie Yu et al.
Background: Lung cancer causes significant mortality, with invasion and metastasis being the main features that cause most cancer deaths. Lymph node metastasis is the primary metastatic route in non-small cell carcinoma (...
Kotaro Sakamoto,Runa Fujimoto,Erina Kamiyama-Ando et al.
Kotaro Sakamoto et al.
Recently, targeted protein degradation has attracted increasing interest as a new drug discovery approach. This method aims to control the function of drug targets by inducing their degradation through protein degradation systems such as th...