In silico and physico-chemical characterization of cluster formation dynamics in peptide solutions [0.03%]
肽溶液中聚集体形成动力学的计算和物理化学表征
Dimitar Kaynarov,Karina Marinova,Rossitsa Marinova et al.
Dimitar Kaynarov et al.
Although antimicrobial peptides are considered one of the most promising alternatives to conventional antibiotics given the alarming increase in bacterial multidrug resistance, many aspects of their mechanism of action remain unclear, in pa...
Identification of gastric cancer biomarkers through in-silico analysis of microarray based datasets [0.03%]
基于芯片的数据集的胃癌生物标志物的鉴定(文献篇)
Arbaz Akhtar,Yasir Hameed,Samina Ejaz et al.
Arbaz Akhtar et al.
Gastric cancer is among the most prevalent cancers worldwide including in Pakistan. Late diagnosis of gastric cancer leads to reduced survival. The present study aimed to investigate biomarkers for early diagnosis and prognosis of gastric c...
Cyclosporine and fedratinib combination therapy via modulating Th17/Treg balance in Rat model of membranous glomerulonephritis [0.03%]
环孢素联合Fedratinib治疗膜性肾炎的Th17/Treg平衡调节作用研究
Ali Ghassabi,Maryam Hosseini,Hemayat Abdoli Goungormaz et al.
Ali Ghassabi et al.
A progressive kidney disease associated with inflammation and the immune system is called membrane glomerulonephritis (MGN). The present study investigatedthe combination of cyclosporine and fedratinib on Th17/regulatory T cells (Tregs) in ...
Delphinidin induces a fast-to-slow muscle fiber type shift through the AMPK signaling pathway in C2C12 myotubes [0.03%]
(delphindin通过AMPK信号通路诱导C2C12肌管向慢肌纤维类型转变)
Motoki Murata,Rina Takahashi,Yuki Marugame et al.
Motoki Murata et al.
Delphinidin, a plant anthocyanidin, suppresses disuse muscle atrophy in mice. However, its effect on muscle fiber type shift is unclear. To examine whether delphinidin affects skeletal muscle fiber type, differentiated C2C12 cells were trea...
Toru Tanaka,Sachiyo Ohashi,Akihiko Takashima et al.
Toru Tanaka et al.
Tau is typically an axonal protein, but in neurons of brains affected by Alzheimer's disease (AD), aggregation of hyperphosphorylated tau in the somatodendritic compartment causes neuronal death. We have previously demonstrated that tau mRN...
Yu Zhang,Yongwei Ren,Tao Zhou et al.
Yu Zhang et al.
The Vav family of guanosine nucleotide exchange factors (GEFs) regulates the phosphorylation of tyrosinase, influencing various physiological and pathological processes by modulating the binding of Rho GTPases to GDP/GTP. Recent research ha...
Identification of a novel mutation in PATL2 gene associated with the germinal vesicle arrest of oocytes [0.03%]
识别PATL2基因的新突变与卵母细胞静止期阻滞有关
Aili Yu,Zhiqing Huang,Hang Shi et al.
Aili Yu et al.
The aim of this study was to investigate the genetic factors of a patient with germinal vesicle arrest in oocytes. Clinical data and blood samples were collected from the patient and some were amplified for high-throughput gene and Sanger s...
Decoding differentially expressed genes to identify potential immunity associated biomarkers in Tuberculosis: An integrative bioinformatics approach [0.03%]
利用整合生物信息学方法鉴定结核病相关的免疫相关标志物基因
Ankur Datta,Divyanshi Gupta,Diya Waryani et al.
Ankur Datta et al.
Tuberculosis (TB) poses a significant threat to the Indian population, with India accounting for 20 % of the global TB cases. The current study aims to identify molecular biomarkers for better diagnostics by comparing the transcriptome sign...
Comparative effects of metformin and varying intensities of exercise on miR-133a expression in diabetic rats: Insights from machine learning analysis [0.03%]
二甲双胍和不同强度运动对糖尿病大鼠miR-133a表达比较研究：来自机器学习分析的启示
Elahe Alivaisi,Sabrieh Amini,Karimeh Haghani et al.
Elahe Alivaisi et al.
This study investigated the effects of metformin, high-intensity interval training (HIIT), and moderate-intensity continuous training (MCT) on miR-133a expression in a diabetic rat model. miR-133a, a microRNA associated with skeletal muscle...
Co-infection of HSV-1 amplicons containing the XPC gene and a human artificial chromosome vector into primary XPC deficient fibroblast cells [0.03%]
HSV-1载有XPC基因的扩增子和人工染色体载体共转染原代XPC缺陷成纤维细胞系
Daniela Moralli,Avi Smith,Jonathan Garlick et al.
Daniela Moralli et al.
Gene therapy for xeroderma pigmentosum (XP), a rare, recessive DNA repair disease, has been considered since defects in XP genes result in severe and debilitating symptoms. Mutations in the XPC DNA repair gene result in a more that 1000-fol...