Recombinant expression and characterization of the family 5 cellulase from Bacillus velezensis in Escherichia coli BL21-CodonPlus (DE3)-RIPL [0.03%]
地衣芽孢杆菌家族5型纤维素酶的克隆表达及性质研究
Dinh Minh Tran,Thi Huyen Nguyen,To Uyen Huynh et al.
Dinh Minh Tran et al.
B. velezensis RB. IBE29 is a chitinolytic bacterium originally isolated from agricultural soil of Vietnam. Previous studies demonstrated this bacterium was a promising chitinase producer, biocontrol agent, and biofertilizer for crop product...
Reduced expression of the serotonin transporter impacts mitochondria in a sexually dimorphic manner [0.03%]
五羟色胺转运蛋白表达降低以性别二态性的方式影响线粒体功能
Bryony N Thorne,Bart A Ellenbroek,Darren J Day
Bryony N Thorne
Neuropsychiatric and neurodevelopmental disorders are complex conditions that arise from a variety of interacting genetic and environmental factors. Among these factors, altered serotonergic signalling and mitochondrial dysfunction are stro...
Structure/function of ATP sulfurylase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthase (hPAPSS) [0.03%]
人3'-磷腺苷5'-磷酸硫酸盐合成酶(hPAPSS)的ATP硫酸化酶结构/功能区研究
K V Venkatachalam,Dhiraj Sinha,Chris Soha et al.
K V Venkatachalam et al.
3'-phosphoadenosine 5'-phosphosulfate (PAPS) is synthesized by PAPS synthase (PAPSS) in two steps. In the first step ATP sulfurylase (ATPS) transfers sulfate group onto adenylyl moiety of ATP to form adenosine 5'-phosphosulfate (APS) and PP...
Construction and evaluation of a prognostic model of autophagy-related genes in hepatocellular carcinoma [0.03%]
肝细胞癌的自噬相关基因预后模型的构建及验证
Yutao He,Bin Du,Weiran Liao et al.
Yutao He et al.
Background: Hepatocellular carcinoma (HCC) is a globally prevalent disease. Our article evaluates risk models based on autophagy- and HCC-related genes and their prognostic value by bioinformatics analytical methods to pr...
The consequences of climate change and male reproductive health: A review of the possible impact and mechanisms [0.03%]
气候变化对男性生殖健康的影响及作用机制综述
R E Akhigbe,P A Oyedokun,T M Akhigbe et al.
R E Akhigbe et al.
A global decline in male fertility has been reported, and climate change is considered a major cause of this. Climate change refers to long-term shifts in temperatures and weather patterns, and results from greenhouse gas emissions like car...
An integrated machine learning framework for developing and validating a prognostic risk model of gastric cancer based on endoplasmic reticulum stress-associated genes [0.03%]
基于内质网应激相关基因的胃癌预后风险模型的开发和验证的集成机器学习框架
Gang Wei,Yan Wang,Ru Liu et al.
Gang Wei et al.
Background: Gastric cancer (GC), a prevalent and deadly malignancy, demonstrates poor survival outcomes. Evidence has emerged indicating that disruptions in endoplasmic reticulum homeostasis are significantly implicated i...
Computational docking of FtsZ: Survey of promising antibiotic compounds [0.03%]
FtsZ的计算对接研究有前景的抗生素化合物概述
Ileini N Espino,Julia Drolet,Ty-Niquia Jones et al.
Ileini N Espino et al.
The bacterial cell-division protein FtsZ has been a promising antibiotic target for over a decade now, but there is still a need for more work in this area. So far there are no FtsZ targeting drugs commercially available. We have analyzed a...
The high-risk model associated with SYTL4 predicts poor prognosis and correlates with immune infiltration in AML [0.03%]
与SYTL4相关的高风险模型预测不良预后并伴有急性髓系白血病中的免疫浸润
Ke Shi,Dan Li,Bo-Hui Peng et al.
Ke Shi et al.
Acute myeloid leukemia (AML) currently lacks a definitive cure. Studies have highlighted the involvement of SYTL4 expression levels in neoplasms, yet its specific roles in AML remain unexplored in the literature. Utilizing the TCGA and XENA...
Analysis of the effect of LMO2 on indicating CD8+ T-lymphocyte infiltration in pan-cancers [0.03%]
LMO2在指示泛癌中CD8⁺T淋巴细胞浸润效果的分析
Yanhong Yu,Mei Yuan,Zhao Zhang et al.
Yanhong Yu et al.
LMO2 is a critical factor in hematopoiesis but widely expressed in kinds of epithelia and solid tumors as well, and it has been demonstrated that increased LMO2 level in some tumor cells exhibits an effect on promoting CD8+ T-lymphocyte inf...
Xiaohua Wang,Xinjuan Qu,Xuelai Liu et al.
Xiaohua Wang et al.
Background: Glioma, the most frequent central nervous system malignancy, is often promoted by the overexpression of Fos-like antigen 1 (FOSL1). However, the regulation of FOSL1 remains unexplored. The present study aimed ...