Xiaomei Li,Minghui Zhang,Yan Wang et al.
Xiaomei Li et al.
Mitochondria are dynamic organelles that continuously adapt their number, morphology, and subcellular distribution in response to physiological and pathological stimuli. This plasticity is governed by a set of highly coordinated processes-c...
Comparative gene network analysis reveals drought resistance mechanisms in Aegilops tauschii genotypes [0.03%]
基因网络比较分析揭示Aegilops tauschii不同基因型的抗旱机制
Mehran Falaknaz,Arash Noshadi,Mahsa Eshaghi et al.
Mehran Falaknaz et al.
Wheat (Triticum aestivum) production faces growing threats from drought caused by climate change, which endangers global food security. Aegilops tauschii, the diploid ancestor of bread wheat, holds vital genetic resources for drought resist...
Automated method for determining the zeta potential of red blood cells via motion tracking in microelectrophoresis [0.03%]
基于微电泳中运动跟踪的红细胞ζ电位自动化测定方法
Oleksii Borikov,Volodymyr Berest,Daniil Liadov
Oleksii Borikov
The surface charge of red blood cells (RBCs), commonly expressed as zeta potential, is a key biophysical parameter influencing RBC aggregation, deformability, and microcirculatory behavior. Despite its physiological and clinical relevance, ...
Do softgel manufacturing or gastric conditions break down carrageenan into poligeenan? [0.03%]
软凝胶制造或胃部条件会将琼脂糖分解为poligeenan吗？
Soo Ah Jin,Qi Fang,Karunakar Sukuru
Soo Ah Jin
Carrageenan (CGN) is a high molecular weight (typically 200-800 kDa) polysaccharide derived from red seaweed. It is used as a food additive and as a functional excipient in pharmaceutical and nutraceutical products. In softgels, CGN can off...
Computational identification of putative mRNA-miRNA signatures in chemoresistant and metastatic triple-negative breast cancer [0.03%]
计算识别化疗耐药和转移性三阴性乳腺癌中潜在的mRNA-miRNA标志物
Mahvash Farajzadeh-Dehkordi,Elham Rezvani Boroujeni,Sina Darzi et al.
Mahvash Farajzadeh-Dehkordi et al.
Triple-negative breast cancer (TNBC) is a heterogeneous malignancy that is recognized as having a high rate of metastasis and limited treatment options. Identifying new molecular signatures for TNBC remains urgent and challenging. In this s...
Hydroxamate formation in the lipopeptide containing siderophore taiwachelin [0.03%]
脂肽色氨酸螯合抗铁素Taiwachelin中羟胺酸的形成
Aaron J Gringer,Kernen P Agwaza,Isabel Da Fonseca et al.
Aaron J Gringer et al.
Cupriavidus taiwanensis is a nitrogen-fixing bacterium found in root nodules of the invasive tropical weed Mimosa pudica. C. taiwanensis has been shown to grow in environments contaminated with heavy metals such as Pb, Cu, and Cd. Taiwachel...
Salvianolic acid B mitigates senescence and promotes osteogenesis of senescent bone marrow mesenchymal stem cells via the PI3K/AKT pathway [0.03%]
salvianolic酸B通过PI3K / AKT途径减轻衰老并促进衰老的骨髓间充质干细胞成骨细胞生成
Shaozi Zhong,Dianxuan Wu,Qize Chen et al.
Shaozi Zhong et al.
Senescence is a major contributor to osteoporosis, with progressive bone loss in later life characterizing age-related osteoporosis. The decline in bone marrow mesenchymal stem cells (BMSCs) function, particularly the reduction in osteogeni...
Stephanie T D Pham,Kristian W Nielsen,Jonas H Graversen et al.
Stephanie T D Pham et al.
Kallistatin is a serine protease inhibitor (serpin) that specifically inhibits tissue kallikrein, a key enzyme involved in kinin generation and vascular homeostasis. While serpins are known to polymerize under certain conditions, the struct...
Comprehensive characterization of the human neural stem cell line HNSC.100 as a versatile model for neurobiological research [0.03%]
人神经干细胞系HNSC.100的全面表征作为神经生物学研究的多功能模型
Estera Jeruzalska,Carolin Ketteler,Elisa Stützenberger et al.
Estera Jeruzalska et al.
Studying neural-related questions is inherently challenging due to the limited number of suitable cell models. Here, we characterize a previously reported immortalized human neural stem cell line, HNSC.100, serving as a robust model for a w...
Evolutionary divergence of nocturnin led to redox regulation in mammalian orthologs [0.03%]
夜宵蛋白的进化分化导致哺乳动物同源物中的氧化还原调控机制
Crystal A Olivas-Rasmussen,Peng Gao,Emil S Rasmussen et al.
Crystal A Olivas-Rasmussen et al.
NADP(H) and NAD(H) are essential cofactors involved in nearly 500 metabolic reactions, making them fundamental to cellular function and redox homeostasis. Loss of redox homeostasis through alterations in NADP(H) regulation has been implicat...