TDP-43 in neurodegeneration and cancer: Decoding the mechanism of mRNA localization and translation [0.03%]
TDP-43在神经退行性疾病和癌症中的作用：解码mRNA定位和翻译的机制
Panjiao Pang,Mingyang Yu,Huixin Ma et al.
Panjiao Pang et al.
The localization and translation of mRNAs play crucial roles in maintaining cellular phenotype and function, with RNA-binding protein (RBP) contributing significantly to these processes. TAR DNA-binding protein of 43 kDa (TDP-43) is an RNA/...
A simple and rapid method for generating antibodies against bovine alphaherpesvirus 1 viral proteins through immunization with virus-infected murine cells [0.03%]
一种通过感染病毒的小鼠细胞免疫来快速高效制备牛疱疹病毒I型多克隆抗体的方法
Jiayu Lin,Xiaozhen Ma,Naifan Zhang et al.
Jiayu Lin et al.
Bovine alphaherpesvirus 1 (BoAHV-1) infects cattle and typically results in significant economic losses for the cattle industry worldwide. Currently, antibodies targeting only a limited number of viral proteins are commercially available. I...
Circulating miRNAs combined with AFP improve diagnostic accuracy for HBV-associated hepatocellular carcinoma [0.03%]
循环miRNA联合AFP提高乙型肝炎相关肝细胞癌诊断准确性
Ngo Dieu Hoa,Dao Phuong Giang,Nguyen Thi Thu Hien et al.
Ngo Dieu Hoa et al.
Background: Early detection of hepatocellular carcinoma (HCC) remains challenging due to the suboptimal diagnostic accuracy of alpha-fetoprotein (AFP). Circulating microRNAs (miRNAs), given their blood stability and role ...
Chinese traditional medicine complex hemorrhoidal analgesic cream promotes wound healing in diabetic rats after anal fistula surgery via Keap1/Nrf2 signaling pathway [0.03%]
基于Keap1/Nrf2信号通路的中医复方痔疮止痛膏促进糖尿病肛瘘术后伤口愈合作用的研究
Jian Liu,Zhitao Yin,Xiaojun Tian et al.
Jian Liu et al.
This study to elucidate how hemorrhoidal analgesic cream (HAC), grounded in the traditional Chinese medicine (TCM) 'elevation and causation' theory, promotes postoperative wound healing after anal fistula surgery in diabetic rats by modulat...
Investigating the cardioprotective effects of Nigella sativa oil on chronic antibiotic use on the myocardium of the left ventricle of male BALB/C mice [0.03%]
investigation into the cardioprotection effect of Nigella sativa oil on chronic antibiotics usage on the left ventricular myocardium of male Balb/c mice
S Saka Olusola,A Komolafe Omobola,A Enye Linus et al.
S Saka Olusola et al.
The abuse of antibiotics is a significant factor in the emergence of antibiotic resistance and the development of several diseases in the modern world. These were conducted to provide information on the combined impact of chronic antibiotic...
Recognition of immunogenomic signature and prognostic value of the subtype of epithelial-mesenchymal transition in breast cancer [0.03%]
识别乳腺癌上皮间质转化亚型的免疫基因组特征及其预后价值
Wei Liang,Zi-Ying Wang,Quan-Feng Shao et al.
Wei Liang et al.
Background: Accumulating evidence has revealed that epithelial-mesenchymal transition (EMT) plays a crucial role in tumor progression and the immune microenvironment, which further results in a high rate of recurrence and...
Breast cancer susceptibility gene 2 upregulation alleviated cardiac hypertrophy in angiotensin II-treated mice [0.03%]
乳腺癌易感基因2上调可缓解血管紧张素Ⅱ致小鼠心脏肥大现象
Kun Liu,Xiao-Xuan Gong,Yong Li et al.
Kun Liu et al.
Loss of breast cancer susceptibility gene 2 (BRCA2) function was found to exacerbate doxorubicin-mediated cardiomyocyte apoptosis and promote heart failure progression. We hypothesized that upregulation of BRCA2 may alleviate hypertrophic c...
Exploring potential biomarkers of NETosis-Related genes in spinal cord injury through machine learning and multi-omics analysis [0.03%]
通过机器学习和多组学分析探索NETosis相关基因在脊髓损伤中的潜在生物标志物
Xinliao Sun,Yuchang Gui,Yuting Lu et al.
Xinliao Sun et al.
Spinal cord injury (SCI) is a serious condition typically caused by mechanical trauma, often resulting in significant motor, sensory, and autonomic dysfunction. It places a heavy burden on individuals, families, and society; however, effect...
Sophia Masterton,Mark Ahearne
Sophia Masterton
Background/aims: Limbal epithelial cells (LECs) have a crucial role in the maintenance of the corneal surface by migrating from the limbus to the cornea and replacing corneal epithelial cells. These cells are subjected to...
Comparative metabolomic of cigar tobacco leaves: A preliminary investigation of potential discriminatory metabolites between Yunnan and Foreign [0.03%]
云南和进口雪茄烟叶代谢组学比较研究及差异代谢物筛查
Gaokun Zhao,Guanghui Kong,Mengxia Li et al.
Gaokun Zhao et al.
A systematic understanding of the metabolic components in cigar tobacco leaves (CTLs) from different ecological regions remains limited. This study aimed to clarify the substance differences between CTLs from Yunnan and major foreign produc...