Ononin combined with Lactobacillus paracasei alleviates DSS-induced ulcerative colitis by ferroptosis via inhibiting JAK2/STAT3 signaling pathway [0.03%]
昂地素联合肠菌乳杆菌通过抑制JAK2/STAT3信号通路缓解葡聚糖硫酸钠诱导的溃疡性结肠炎的作用及机制研究
Mei Huang,Feng Yang,Ju-Cai Song et al.
Mei Huang et al.
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease with a complex pathogenesis and limited treatment options. This study aimed to evaluate the therapeutic effect of Ononin combined with Lactobacil...
Microstructural analysis of the human ventricular myocardium in subjects with Type-II Diabetes [0.03%]
II型糖尿病患者的室壁心肌组织微结构分析
Haritha Keerthi,Salma P Ramirez,Mario M Corral et al.
Haritha Keerthi et al.
Prolonged onset of Type-II Diabetes is known to induce structural and mechanical remodeling in the ventricular myocardium or heart wall. This study aimed to compare the microarchitecture, fiber organization, and stiffness of left ventricula...
Classical conditioning of Purkinje cell responses in vitro produces in vivo-like simple spike suppressions during the conditional stimulus [0.03%]
经典的条件反射可以训练小脑浦肯野细胞的单纯突触抑制反应
Artem Gornov,Thiago C Moulin,Fredrik Johansson
Artem Gornov
An in vitro model of classical conditioning could improve our understanding of underlying mechanisms thanks to controlled pharmacological manipulation and negligeable perturbations from external networks. Here, using mice cerebellar slices ...
Preliminary study of cyto-impedance: Molecular profiling of functional impedance in motility-promoting treatment of normal cells [0.03%]
功能性阻抗促进正常细胞运动的细胞阻抗初步研究
Chang-Zhi Li,Hong-Juan Zhou,Jin-Dong Chen et al.
Chang-Zhi Li et al.
Aims: Cell motility is critical for physiological processes including wound healing. However, high concentrations of motility-promoting agents may suppress cellular migration; this newly observed phenomenon warrants furth...
A systematic review and meta-analysis of the relationship between neuroinflammation and blood-brain barrier based on in vitro models [0.03%]
基于体外模型的神经炎症与血脑屏障关系的系统评价和meta分析
Junwei Zhao,Anyongqi Wang,Xiang Li
Junwei Zhao
The blood-brain barrier (BBB) plays a crucial role in maintaining homeostasis within the central nervous system (CNS). Neuroinflammation disrupts the integrity of the BBB. However, there is a lack of comprehensive synthesis of in vitro evid...
Comprehensive multi-omics analysis reveals RUNX1's prognostic value, immune associations, and MUC13-Mediated mechanistic role in hepatocellular carcinoma pathogenesis [0.03%]
全面的多组学分析揭示了RUNX1在肝细胞癌预后价值、免疫关联及MUC13介导的作用机制中的作用
Tahani Ahmad ALMatrafi
Tahani Ahmad ALMatrafi
Hepatocellular carcinoma (HCC) is a biologically and clinically heterogeneous malignancy, posing major challenges for early diagnosis, prognostic prediction, and therapeutic intervention. The Runt-related transcription factor (RUNX) family,...
Antibacterial activity of peptide derivatives of dermaseptins against multidrug-resistant Klebsiella pneumoniae and Staphylococcus epidermis [0.03%]
色胺肽衍生物对多重耐药肺炎克雷伯氏菌和表皮葡萄球菌的抗菌活性研究
Houda Haddad,Reyadh R Al-Rashidi,Ahmed Loghmari et al.
Houda Haddad et al.
The emergence of infections caused by multi-drug resistant bacteria (MDR) to antibiotic treatments poses a significant challenge in the healthcare field. Indeed, the resistance of MDR such as: Klebsiella pneumonia and Staphyloccus epidermid...
Treating myocardial infarction combined with depression via regulating M1/TNF-α/TNFR1/NF-κB [0.03%]
调控M1/TNF-α/TNFR1/NF-κB治疗心肌梗死合并抑郁的研究进展
Lijun Zhang,Meiyan Liu,Haiyang Chen
Lijun Zhang
Objective: To further explore the underlying mechanism by which the traditional Mongolian medicine Anshen Buxin Liuwei Pills (ABLP) alleviates cardiac dysfunction and depressive behaviors in a model of myocardial infarcti...
Identification and analysis of small RNAs in exosome-like nanoparticles derived from onion (Allium cepa L.) [0.03%]
洋葱（Allium cepa L.）来源类囊体纳米颗粒中的小RNA的鉴定与分析
Zhaofeng Liang,Yuning Gu,Jiajia Song et al.
Zhaofeng Liang et al.
Small RNAs (sRNAs) in plant-derived exosome-like nanoparticles (PELNs) have attracted considerable attention as biologically active substances that play a crucial role in cross-kingdom regulatory processes. However, there is insufficient re...
Live imaging of human airway epithelial repair in precision-cut lung slices after targeted cell damage [0.03%]
三维人类类器官和肺切片模型中上呼吸道黏膜损伤与修复的实时成像研究
Lara Gentemann,Fabian Röpken,Philipp Joel Mroch et al.
Lara Gentemann et al.
Precision-cut lung slices (PCLS) are a complex three-dimensional ex vivo model system comprised of all resident cell types of the lung, thus closely mimicking the in vivo situation in regards to structural composition and function. The here...