Double burden: microfilariae infection amplifies metabolic costs of moult in breeding male village weavers (Ploceus cucullatus) [0.03%]
双重负担：微丝虫感染加剧了繁殖期雄性村文鸟(Ploceus cucullatus)换羽的代谢成本
Felix A Andong,Ezekiel S Mayowa,Praise O Nwanozie et al.
Felix A Andong et al.
Breeding male birds face high energetic demands due to simultaneous investment in reproduction and feather moult, yet the metabolic consequences of parasitic infection during this period are poorly understood. To address this gap, we focuse...
Polygonatum sibiricum polysaccharides ameliorate diabetes-induced vascular endothelial injury partly through Nrf2/GPX4 activation [0.03%]
Polygonatum sibiricum多糖通过激活Nrf2/GPX4改善糖尿病所致血管内皮损伤
Dongdong Wu,Jing Zhao,Qifan Yang et al.
Dongdong Wu et al.
Diabetes mellitus is a chronic metabolic disorder in which endothelial dysfunction plays a pivotal role in disease progression. Polygonatum sibiricum polysaccharides (PSP) exhibit multiple biological activities, including antioxidant effect...
Exploring cannabinoid receptor CB1 autophagy and the obesity phenotype of p62-deficient mice [0.03%]
CB1受体自噬和p62缺陷小鼠肥胖表型的研究
Christina Keller,Sebastian Rading,Bahar Candur et al.
Christina Keller et al.
The endocannabinoid system (ECS) and the autophagy receptor p62 are both implicated in metabolic regulation and obesity, yet the mechanisms linking these pathways remain unclear. Here, we investigated whether p62 modulates CB1 receptor (CB1...
Comprehensive evaluation of sacchachitosan-based transdermal films for wound care: Physical, chemical, and biological parameters [0.03%]
基于Sacchachitosan的透皮给药膜用于伤口护理的全面评价：物理、化学和生物参数
Sneha Paul,C Sheela Sasikumar
Sneha Paul
In the present investigation, the development and comparative assessment of sacchachitosan-based transdermal films loaded with biosynthesized silver nanoparticles (AgNPs) for wound-healing applications were reported. Sacchachitosan, a funga...
Solution-state nuclear magnetic resonance studies of the Salmonella typhimurium tryptophan synthase complex [0.03%]
溶液核磁共振法对沙门菌色氨酸酶复合物的研究
Rebecca N D&#x;Amico,Somnath Mondal,Dennis S Winston et al.
Rebecca N D&#x;Amico et al.
Tryptophan synthase (TS) is an allosteric bi-enzyme complex that catalyzes the final steps of l-tryptophan biosynthesis through tightly coupled α- and β-subunit reactions. Understanding how conformational dynamics mediate its catalytic ef...
A comprehensive review on structural, chemical, and functional perspectives of dietary polysaccharide-driven gut microbiota modulation: Mechanisms and challenges [0.03%]
膳食多糖驱动的肠道微生物组调节作用：结构、化学和功能视角及其机制与挑战综述
Athira Jayasree Subhash,Mohamed Abdin,Gafar Babatunde Bamigbade et al.
Athira Jayasree Subhash et al.
Polysaccharides in the diet have been increasingly recognized as major modulators of gut microbiota and multifunctional ingredients in food systems. Despite extensive research on various polysaccharides regarding their prebiotic activities,...
Fluorescently engineered KRAS-mutant organoids as versatile tools for in vitro and in vivo cancer modeling [0.03%]
荧光工程KRAS突变器官体作为体外和体内癌症建模的多功能工具
Alireza Savadipour,Krishna S Tummala,Eric S Muise et al.
Alireza Savadipour et al.
Organoids have emerged as advanced models in cancer research, offering superior physiological relevance compared to traditional 2D cell cultures. They mimic the three-dimensional architecture and tumor clonal heterogeneity, providing more a...
Vaccination modality and injection site influence the immune response and protection against sea lice Lepeophtheirus salmonis infestation in Atlantic salmon (Salmo salar) [0.03%]
接种方式和注射部位影响大西洋鲑鱼（Salmo salar）对海水鲺（Lepeophtheirus salmonis）寄生的免疫反应和保护力
Elisabeth Gislefoss,Amr Gamil,Øystein Evensen
Elisabeth Gislefoss
Sea lice (Lepeophtheirus salmonis) infestations represent a challenge to Atlantic salmon (Salmo salar L.) aquaculture. We evaluated recombinant peroxinectin-like proteins (LsPxtl-1 and LsPxtl-2) and whole sea lice (WSL) crude proteins as va...
Oxysterol-binding protein-related protein 6 regulates neuronal morphology and migration of cerebellar granule cells during cerebellar development in vivo [0.03%]
黄酮醇受体相关蛋白6在小脑发育过程中调节颗粒细胞的形态和迁移
Shinya Mochizuki,Wataru Nishimura,Masanori Takahashi et al.
Shinya Mochizuki et al.
Oxysterol-binding protein (OSBP)-related protein (ORP) 6, a member of subfamily III of the ORP family, localizes at endoplasmic reticulum-plasma membrane contact sites and is involved in regulating the turnover of the lipid composition of t...
Structural and morphological modulation of the myocardium by Dioscorea bulbifera saponins in experimentally induced cardiotoxicity [0.03%]
薯蓣珠芽皂苷对实验性心肌毒性的结构性和形态学的调节作用研究
Olusola S Saka,Omobola A Komolafe,Oluwadare Ogunlade et al.
Olusola S Saka et al.
Background: This study investigated the ameliorative potential of a saponin derived from Dioscorea bulbifera bulbils in mitigating experimentally induced cardiotoxicity in adult male Wistar rats. ...