Purification, and characterization of a new pro-coagulant protein from Iranian Echis carinatus venom [0.03%]
从中东沙尘蛇毒中纯化、鉴定一种新的促凝血蛋白
Sayeneh Khodadadi,Hadi Rabiei,Soroush Sardari et al.
Sayeneh Khodadadi et al.
This work aimed to purify the proteins that cause blood coagulation in the venom of the Iranian Echis carinatus snake species in a comprehensive manner. Gel filtration chromatography (GFC), Ion exchange chromatography (IEC), and Size Exclus...
Effect of exercise-induced Neutrophil maturation on skeletal muscle repair in vitro [0.03%]
运动诱导的中性粒细胞成熟对体外骨骼肌修复的影响
Jae Yeon Park,Tae Yeon Kim,Song Won Woo et al.
Jae Yeon Park et al.
Neutrophils as first line defender initiate a cascade of healing process immediately after muscle injury. At muscle injury site, neutrophils remove damaged muscle fibers and recruit other immune cells and these functions show in mature neut...
Computational exploration of SLC14A1 genetic variants through structure modeling, protein-ligand docking, and molecular dynamics simulation [0.03%]
基于结构建模、蛋白质-配体对接及分子动力学模拟的SLC14A1遗传变异计算研究
Tamanna Sultana,Sadia Islam Mou,Dipankor Chatterjee et al.
Tamanna Sultana et al.
The urea transporter UT-B1, encoded by the SLC14A1 gene, has been hypothesized to be a significant protein whose deficiency and dysfunction contribute to the pathogenesis of bladder cancer and many other diseases. Several studies reported t...
The expression system affects the binding affinity between p75NTR and proNGF [0.03%]
表达系统影响proNGF与p75NTR结合亲和力
Mami Hino,Masayuki Nakanishi,Hiroshi Nomoto
Mami Hino
ProNGF (nerve growth factor) is a precursor of NGF and a signaling peptide exerting opposite effects on neuronal cells, i.e., apoptotic or neuritogenic. The conflicting biological activity of proNGF depends on the relative levels of two mem...
Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux [0.03%]
阿贝米克利和Vacuolin-1通过加速自噬流减少易聚集的TDP-43累积
Yoshinori Tanaka,Lina Kozuma,Hirotsugu Hino et al.
Yoshinori Tanaka et al.
(Macro)autophagy is a cellular degradation system for unnecessary materials, such as aggregate-prone TDP-43, a central molecule in neurodegenerative diseases including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Abe...
Dongling Li,Ling Lin,Fan Xu et al.
Dongling Li et al.
Crotonylation is an importantly conserved post-translational modification, which is completely different from acetylation. In recent years, it has been confirmed that crotonylation occurs on histone and non-histone. Crotonylated Histone pri...
The effects of different durations of exposure to hypomagnetic field on the number of active mitochondria and ROS levels in the mouse hippocampus [0.03%]
不同低磁场暴露持续时间对小鼠海马体活跃线粒体数量及ROS水平影响的比较研究
Lanxiang Tian,Jie Ren,Yukai Luo
Lanxiang Tian
Reactive oxygen species (ROS) are one of the potential molecules in response to a hypomagnetic field (HMF), and exposure to an HMF for eight weeks led to an increase in ROS levels in the whole hippocampus area in mice. ROS are mainly derive...
Damilare Emmanuel Rotimi,Matthew Iyobhebhe,Elizabeth Temidayo Oluwayemi et al.
Damilare Emmanuel Rotimi et al.
The mitophagy process, a type of macroautophagy, is the targeted removal of mitochondria. It is a type of autophagy exclusive to mitochondria, as the process removes defective mitochondria one by one. Mitophagy serves as an additional level...
Glioblastoma U-87 cell electrotaxis is hindered by doxycycline with a concomitant reduction in the matrix metallopeptidase-9 expression [0.03%]
多西环素通过同时减少基质金属蛋白酶-9的表达来阻碍胶质母细胞瘤U-87细胞的电导向运动
Hui-Fang Chang,Ji-Yen Cheng
Hui-Fang Chang
Electric fields (EF) play an essential role in cancer cell migration. Numerous cancer cell types exhibit electrotaxis under direct current electric fields (dcEF) of physiological electric field strength (EFs). This study investigated the ef...
SH3GL2 and MMP17 as lung adenocarcinoma biomarkers: a machine-learning based approach [0.03%]
基于机器学习的SH3GL2和MMP17作为肺腺癌生物标志物的方法
Zengjian Tian,Shilong Yu,Ruizhi Cai et al.
Zengjian Tian et al.
Objective: Using bioinformatics machine learning methods, our research aims to identify the potential key genes associated with Lung adenocarcinoma (LUAD). ...