FZD7 Inhibitor SRI Attenuates High Glucose-Induced Retinal Pigment Epithelial Cell Injury Accompanied by Ferroptosis-Associated Changes via Suppression of the Wnt/β-Catenin Pathway [0.03%]
FZD7抑制剂SRI通过抑制Wnt/β-catenin信号通路减弱高糖诱导的视网膜色素上皮细胞损伤及铁死亡相关改变
Jiaojiao Jiang,Liu Zheng,Liwu Tan et al.
Jiaojiao Jiang et al.
Purpose: This study investigated the protective effects of the Frizzled-7 (FZD7) inhibitor SRI against high glucose-induced injury in human retinal pigment epithelial (ARPE-19) cells. It also explored the underlying mecha...
Metabolic and Glycemic Effects of Orforglipron, a GLP-1 Receptor Agonist, in Adults With or Without Diabetes: A Network Meta-Analysis of Randomised Clinical Trials [0.03%]
胰高血糖素样肽1受体激动剂奥普格利汀在有或无糖尿病成人中的代谢及糖耐量效应：随机临床试验的网状meta分析研究
Ahmed W Hageen,Ahmed Farid Gadelmawla,Ahmad Omar Saleh et al.
Ahmed W Hageen et al.
Background and aim: Orforglipron (OFG), an oral, non-peptide glucagon-like peptide-1 receptor agonist (GLP-1 RAs), showed potential benefits for type 2 diabetes mellitus (T2DM) and obesity. Its dose-response effects on bo...
Comparative Efficacy and Safety of Tirzepatide in Asian and Non-Asian Adults With Obesity Without Diabetes: A Systematic Review and Meta-Analysis [0.03%]
司美格鲁肽治疗非糖尿病肥胖亚洲和非亚洲成人疗效和安全性的系统评价和meta分析
A B M Kamrul-Hasan,Ibrahim Khalil,Deep Dutta et al.
A B M Kamrul-Hasan et al.
Introduction: Tirzepatide, a dual GIP/GLP-1 receptor agonist, produces substantial weight loss in adults with obesity. Given ethnic differences in obesity phenotype and cardiometabolic risk, this systematic review and met...
Associations between Serum Zinc Levels and the Presence of Distal Symmetric Polyneuropathy in Patients with Type 2 Diabetes Mellitus [0.03%]
血清锌水平与2型糖尿病周围神经病变的关系研究
Hosseinali Mohammadi,Firozeh Sajedi,Younes Mohammadi
Hosseinali Mohammadi
Introduction: Distal Symmetric Polyneuropathy Is the Most Common Form of Diabetic Neuropathy and a Major Source of Morbidity in Type 2 Diabetes. Oxidative Stress Plays a Key Role in Its Pathogenesis, and Zinc-An Essential...
Clinical Presentation and Early Outcomes of Congenital Endocrine Salt-Wasting Syndromes Unrelated to 21-Hydroxylase Deficiency [0.03%]
与21-羟化酶缺乏无关的先天性内分泌低钠血症综合征的临床表现和早期结局
Vittorio Ferrari,Valentina Assirelli,Emma Bonaguri et al.
Vittorio Ferrari et al.
Objective: Congenital endocrine salt-wasting syndromes unrelated to 21-hydroxylase deficiency are rare disorders with overlapping clinical and biochemical features at presentation. This study described the spectrum, early...
Comment on 'Role of Evogliptin for Intra-Class Therapeutic Interchange in Patients With Type 2 Diabetes Mellitus: Subgroup Analysis From A Multi-Centre, Prospective, Observational Study (REVISE Study)' [0.03%]
对“埃伏西普在2型糖尿病患者组间治疗置换中的作用：来自一项多中心、前瞻性、观察性研究（修订研究）”的评述
Aman Batool Hashmi,Syeda Bareera,Muhammad Faizan Khan
Aman Batool Hashmi
Comment on 'A Prospective Evaluation of Glucagon Stimulation Test Safety in Adults With Chronic Moderate-to-Severe Traumatic Brain Injury' [0.03%]
对“糖原素刺激试验在慢性中重度创伤性脑损伤成人患者中的安全性前瞻性评估”的评论
Aisha Zahir,Muhammad Faizan Khan,Gulalai Tariq
Aisha Zahir
Placebo-Referenced Class-Level Treatment Effects on Chronic Kidney Disease Progression in Patients With Diabetes: A Network Meta-Analysis [0.03%]
糖尿病患者的慢性肾脏病进展的安慰剂参照治疗效果：网状 meta 分析
Ravi Kumar Pandey,Maryam Imran,Ishba Manal et al.
Ravi Kumar Pandey et al.
Background and aim: Multiple pharmacologic therapies reduce chronic kidney disease (CKD) progression in patients with diabetes; however, the absence of head-to-head trials and heterogeneity across studies limits the inter...
Knowledge, Attitudes and Practices on the Use of Antidiabetic Medications for Weight Loss: A Cross-Sectional Study in the Lebanese Population [0.03%]
关于抗糖尿病药物减肥的知识、态度和行为：黎巴嫩人群的横断面研究
Rim Masri,Hekmat Kaakour,Hasnaa Hamdan et al.
Rim Masri et al.
Background: The growing use of antidiabetic medications for weight loss has raised concerns about public awareness, safety and appropriate use. This study assessed knowledge, attitudes and practices (KAP) regarding antidi...
Reassessing Agreement Between Point of Care and Laboratory Triglyceride Measurements in High Risk Pregnancy [0.03%]
高危妊娠时床旁与实验室测量甘油三酯结果一致性的再评估
Faizan Ahmed,Ahmed Raza,Abdullah Aman et al.
Faizan Ahmed et al.