Putting objects in context: A prefrontal-hippocampal-perirhinal cortex network [0.03%]
物体的情境:前额叶-海马体-周皮质网络
G R I Barker,E C Warburton
G R I Barker
When we encounter an object, we spontaneously form associations between the object and the environment in which it was encountered. These associations can take a number of different forms, which include location and context. A neural circui...
Distributed interactive brain circuits for object-in-place memory: A place for time? [0.03%]
物体位置记忆的分布式交互脑回路:时间的位置?
John P Aggleton,Andrew J D Nelson
John P Aggleton
Rodents will spontaneously learn the location of an individual object, an ability captured by the object-in-place test. This review considers the network of structures supporting this behavioural test, as well as some potential confounds th...
Laurel S Morris,Jordan G McCall,Dennis S Charney et al.
Laurel S Morris et al.
This review aims to synthesise a large pre-clinical and clinical literature related to a hypothesised role of the locus coeruleus norepinephrine system in responses to acute and chronic threat, as well as the emergence of pathological anxie...
Impairments in sensory-motor gating and information processing in a mouse model of Ehmt1 haploinsufficiency [0.03%]
Ehmt1单倍剂量不足小鼠模型中感觉运动门控和信息处理的缺陷
Brittany A Davis,François David,Ciara ORegan et al.
Brittany A Davis et al.
Regulators of chromatin dynamics and transcription are increasingly implicated in the aetiology of neurodevelopmental disorders. Haploinsufficiency of EHMT1, encoding a histone methyltransferase, is associated with several neurodevelopmenta...
Kaori Takehara-Nishiuchi
Kaori Takehara-Nishiuchi
The hippocampus rapidly forms associations among ongoing events as they unfold and later instructs the gradual stabilisation of their memory traces in the neocortex. Although this two-stage model of memory consolidation has gained substanti...
Recent advances in functional neuroimaging analysis for cognitive neuroscience [0.03%]
认知神经科学的脑影像学分析新进展
Nitin Williams,Richard N Henson
Nitin Williams
Functional magnetic resonance imaging and electro-/magneto-encephalography are some of the main neuroimaging technologies used by cognitive neuroscientists to study how the brain works. However, the methods for analysing the rich spatial an...
Comparison of conventional and rapid-acting antidepressants in a rodent probabilistic reversal learning task [0.03%]
快速抗抑郁药与传统抗抑郁药在概率逆转学习任务中的比较研究
Matthew P Wilkinson,John P Grogan,Jack R Mellor et al.
Matthew P Wilkinson et al.
Deficits in reward processing are a central feature of major depressive disorder with patients exhibiting decreased reward learning and altered feedback sensitivity in probabilistic reversal learning tasks. Methods to quantify probabilistic...
Caitlín Ní Chasaide,Marina A Lynch
Caitlín Ní Chasaide
Neuroinflammation is now recognised as an important contributory factor in the progression of Alzheimer's disease and probably also in the early stages of the disease. It is likely that this derives largely from aberrant activation of micro...
Precommissural and postcommissural fornix microstructure in healthy aging and cognition [0.03%]
健康老龄化和认知与穹窿前连合和后连合微结构的关系
Bethany M Coad,Emma Craig,Rebecca Louch et al.
Bethany M Coad et al.
The fornix is a key tract of the hippocampal formation, whose status is presumed to contribute to age-related cognitive decline. The precommissural and postcommissural fornix subdivisions form respective basal forebrain/frontal and dienceph...
G-protein αq gene expression plays a role in alcohol tolerance in Drosophila melanogaster [0.03%]
果蝇g蛋白αq基因表达在酒精耐受中的作用研究
Benjamin Aleyakpo,Oghenetega Umukoro,Ryan Kavlie et al.
Benjamin Aleyakpo et al.
Ethanol is a psychoactive substance causing both short- and long-term behavioural changes in humans and animal models. We have used the fruit fly Drosophila melanogaster to investigate the effect of ethanol exposure on the expression of the...