The LOAD2 mouse model of late-onset alzheimer's disease exhibits an accelerated onset of locomotor and anxiety deficits [0.03%]
LOAD2小鼠模型表现出运动和焦虑障碍加速发作的现象
Shinwon Kang,Ashish Kadia,Junhui Wang et al.
Shinwon Kang et al.
Late-onset alzheimer's disease is the most common form of dementia, and it arises from complex genetic and environmental interactions. Preclinical models that replicate the slow progression and long prodromal phase of late-onset alzheimer's...
Re-visiting cognitive reserve: The importance of multiple brain measures [0.03%]
重新审视认知储备：多种脑测量指标的重要性
Richard N Henson
Richard N Henson
The term 'cognitive reserve' broadly refers to better-than-expected cognitive abilities in old age, presumed to reflect environmental/lifestyle factors earlier in life. This commentary addresses the question of what determines 'better than ...
Assessing oligodendrocyte and myelin alterations following absence seizures in a rat model of GRIN2B neurodevelopmental disorder [0.03%]
GRIN2B神经发育障碍大鼠模型中无发作后少突胶质细胞和髓鞘的变化评估
Zita Francsics,Eleni Tsoukala,Katerina Hristova et al.
Zita Francsics et al.
Neuronal activity can modulate myelination throughout life, influencing circuit function and behaviour. Pathological changes in neuronal activity have been associated with myelin remodelling in a rat model of idiopathic absence seizures, ra...
Katherine R Birditt,Alasdair Coles,Amy Doyle et al.
Katherine R Birditt et al.
On 10-11 September 2025, the Cambridge Neuroscience Interdisciplinary Research Centre held its eighth biennial symposium on the topic of Interventions and Recovery. The meeting saw basic and clinical neuroscientists come together from Cambr...
The neurobiological rationale for improving paternity leave in academia and beyond [0.03%]
学术界及更广泛范围改善父亲育儿假的神经生物学依据
Paul G Anastasiades,Valentina Mosienko,Antonia Tzemanaki
Paul G Anastasiades
The UK National Mouse Genetics Network: Translating genetic findings using preclinical mouse models to better understand neurodevelopmental, neuropsychiatric and neurodegenerative disorders [0.03%]
英国小鼠基因网络：利用临床前模型将基因研究成果转化为神经发育、神经精神和神经退行性疾病的研究成果
Sevda T Boyanova,Nicholas E Clifton,Karolina Dec et al.
Sevda T Boyanova et al.
The power of public engagement: Reflections on bring your own brain 2025 [0.03%]
公众参与的力量——BYOB(自带头脑)2025会议回顾
Susannah C Walker
Susannah C Walker
Bethany Facer,Dorothy Tse
Bethany Facer
This year's British Neuroscience Association (BNA) International Festival of Neuroscience, held from 27 to 30 April 2025 at the iconic ACC Liverpool, offered a remarkable convergence of scientific enthusiasm and professional networking. Wit...
Epilepsy Research Institute Partner Symposium: Radically advancing research into epilepsy [0.03%]
癫痫研究协会合作伙伴研讨会：推动癫痫研究的创新模式
Amy Richardson,Jose Prius Mengual,Nicolas Marichal et al.
Amy Richardson et al.
On 28 April 2025, the Epilepsy Research Institute Symposium at BNA2025 brought together four early career researchers to present on their findings in different areas of fundamental epilepsy research. Here, we provide a snapshot of the Sympo...