A Clinical Prediction Model for Early Colectomy in Patients With Severe Ulcerative Colitis Treated With Tacrolimus [0.03%]
他克莫司治疗重症溃疡性结肠炎患者早期结肠切除术的临床预测模型
Hikaru Shimizu,Kazuki Kakimoto,Mai Utsumi et al.
Hikaru Shimizu et al.
Background/aims: Tacrolimus is an effective treatment option for refractory ulcerative colitis; however, some patients still require colectomy due to insufficient response. Early assessment of surgical risk is clinically ...
Prediction of Hepatocellular Carcinoma After Direct-Acting Antiviral Therapy Using Agile 3+ and End-of-Treatment Alpha-Fetoprotein Levels in Patients With Hepatitis C [0.03%]
基于Agile 3+和直接抗病毒治疗结束时的甲胎蛋白预测丙肝患者的肝癌发生率
Akifumi Kuwano,Masayoshi Yada,Kosuke Tanaka et al.
Akifumi Kuwano et al.
Direct-acting antivirals (DAAs) have dramatically improved sustained virological response (SVR) rates in patients with hepatitis C virus (HCV) infection. However, the risk of hepatocellular carcinoma (HCC) remains even after achieving SVR. ...
Study of Types of Pathophysiologic Patterns of Chronic Constipation and Its Correlation With Clinical Features [0.03%]
慢性便秘病证类型的病理生理学研究及临床特征相关性分析
Ajay Kumar Jain,Sudhanshu Yadav,Suchita Jain et al.
Ajay Kumar Jain et al.
Background: Chronic constipation is common in India. Identifying its subtypes is essential not only to treat appropriately but also to improve quality of life. ...
Amanda Ferreira Paes Landim Ramos,Silvana Barbosa Santiago,Felipe Augusto de Sousa Moraes et al.
Amanda Ferreira Paes Landim Ramos et al.
Background and aim: Helicobacter pylori is an oncobacteria that infects about half of the world's population and has a well-established role in the etiology of gastric diseases. Lately, this infection has also been associ...
3D Imaging of Crohn's Disease Strictures: A Novel Tool to Enhance Patient Understanding and Support Multidisciplinary Decision-Making [0.03%]
克罗恩病狭窄的三维影像：一种增强患者理解和支持多学科决策的新工具
Ashish Srinivasan,Gauraang Bhatnagar,Thomas C Shepherd
Ashish Srinivasan
Small bowel strictures in Crohn's disease vary in morphology and often require multimodal medical, endoscopic, or surgical management. We present a case of a 36-year-old male with multifocal post-operative stricturing small bowel Crohn's di...
Gastroesophageal Reflux Disease (GERD) and Risk of Incident Acute Myocardial Infarction: A Systematic Review and Meta-Analysis of Cohort Studies [0.03%]
胃食管反流病与急性心肌梗死发病风险的关系：队列研究的系统评价和meta分析
Tinsae Anebo,Thitiphan Srikulmontri,Karecia Byfield et al.
Tinsae Anebo et al.
Aims: Recent evidence suggests that gastroesophageal reflux disease (GERD) is associated with cardiovascular diseases, including increased coronary artery calcification. However, whether GERD is a risk factor for acute my...
Viewpoint: The Use of Antimycobacterial (Anti-MAP) Therapies in the Treatment of Active Luminal Crohn's Disease [0.03%]
观点文章：抗分枝杆菌疗法治疗活动性克罗恩病的研究进展
Paul Pavli,Peter R Gibson
Paul Pavli
Mycobacterium avium subspecies paratuberculosis (MAP) as the infectious cause of Crohn's disease and the use of antimycobacterial (anti-MAP) therapies in its treatment remain topics of controversy. A major limitation accepting this view is ...
Diagnosis, Treatment Patterns and Eradication Success for Helicobacter pylori Infections in China: A Retrospective Observational Real-World Study [0.03%]
中国幽门螺杆菌感染的诊断、治疗模式及根除成功的回顾性观察研究
Changqin Xu,Wensheng Pan,Yan Zhao et al.
Changqin Xu et al.
Background and aim: In Mainland China, Helicobacter pylori infection is prevalent in about 50% of adults. However, there is limited real-world evidence on its diagnosis and treatment patterns. This study investigated diag...
Association Between Digestive Diseases, Nighttime Sleep, and Depressive Symptoms Among the Middle-Aged and Elderly Adults: A Mediation Analysis [0.03%]
消化系统疾病、夜间睡眠与中老年人抑郁症状的关系：中介效应分析
Congcong Cheng,Dinghui Guo,Xu Cao et al.
Congcong Cheng et al.
Objective: To explore the mediating effect of nighttime sleep duration between digestive diseases and depressive symptoms among middle-aged and elderly adults, so as to guide clinical intervention and treatment of depress...
Induction Efficacy and Safety of Upadacitinib for Active Crohn's Disease in Japanese Patients: A Multicenter Retrospective Study [0.03%]
乌帕替尼治疗日本活动性克罗恩病患者的有效性和安全性：多中心回顾性研究
Takuto Saiki,Junji Umeno,Yuichi Matsuno et al.
Takuto Saiki et al.
Background: While Western real-world studies have demonstrated the therapeutic effect of upadacitinib in Crohn's disease (CD), data on Asian populations are scarce, and no real-world data from Japan have been reported. Th...