Gut Microbiota and Extraintestinal Cancers: Mechanistic Insights and Microbiome-Targeted Interventions [0.03%]
肠道微生物群与肠外癌症：机制见解和针对微生物组的干预措施
Rishi Chowdhary,Manjeet Kumar Goyal,Kirti Arora et al.
Rishi Chowdhary et al.
The gut microbiota is a dynamic community of bacteria, viruses, fungi, and archaea that plays a pivotal role in regulating host immunity, metabolism, and systemic homeostasis. Dysbiosis, characterized by an imbalance in the microbial compos...
Comparison of Changes in Biomarkers With Changes in Endoscopic Scores in Patients With Ulcerative Colitis: A Single-Center, Retrospective, Observational Study [0.03%]
溃疡性结肠炎患者生物标志物变化与内镜评分变化的比较：一项单中心回顾性观察研究
Yosuke Yamada,Natsuki Ishida,Tomohiro Takebe et al.
Yosuke Yamada et al.
Aim: Fecal occult blood concentration, fecal calprotectin (FC) level, serum C-reactive protein (CRP) level, and erythrocyte sedimentation rate (ESR) are valuable biomarkers for ulcerative colitis (UC). However, their clin...
Efficacy and Safety of Switching From Intravenous to Subcutaneous Vedolizumab in Japanese Patients With Ulcerative Colitis: A Study Focusing on Injection-Site Reactions [0.03%]
溃疡性结肠炎患者从静脉注射维多珠单抗转换为皮下给药的疗效和安全性：重点关注注射部位反应的研究
Makoto Furuya,Kiichiro Yoza,Takeshi Yonezawa et al.
Makoto Furuya et al.
Background/aims: The subcutaneous (SC) formulation of vedolizumab is available as an alternative to the intravenous (IV) formulation in patients with ulcerative colitis (UC). However, data from Asian patients are limited,...
Oral Microbiome and Constipation: A Causal Link Revealed by Mendelian Randomization [0.03%]
口腔微生物组和便秘：孟德尔随机化揭示的因果关系
Ziyi Zhao,Jinlian Ling,Jiashu Chen
Ziyi Zhao
Background: Constipation affects approximately 15.3% of the global population. While the gut microbiome's role in constipation has been studied, the causal relationship between the oral microbiome and constipation remains...
Gastric Microbiome Alterations in Sepsis-Related Gastrointestinal Bleeding: Two Case Reports and Literature Review [0.03%]
脓毒症相关消化道出血患者胃微生物群的改变：2例报告及文献复习
Fangjie Fu,Chen Zhang,Zhengying Xu et al.
Fangjie Fu et al.
Sepsis, characterized by life-threatening organ dysfunction resulting from an uncontrolled response to infection, can impact various systems of the body, including the digestive system. Prior research has identified sepsis as a significant ...
Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Patients With Inflammatory Bowel Disease: A Real-World Comparison of Combination Therapy Versus Monotherapy [0.03%]
炎症性肠病患者抗肿瘤坏死因子α治疗无应答的现状研究：联合疗法与单药疗法的比较
Faris Chater,Maja Kopczynska,Mahdi Saeidinejad et al.
Faris Chater et al.
Objectives: The success of anti-TNFα agents has changed the landscape of treatment for inflammatory bowel diseases (IBD). One major limitation to this success is the secondary loss of response (sLOR) phenomenon. Combinat...
Artificial Intelligence-Driven Colonoscopy: A Systematic Review and Network Meta-Analysis on System Performance for Colorectal Neoplasia Detection [0.03%]
基于人工智能的结肠镜检查：结直肠肿瘤检测系统性能的系统评价和网状meta分析
F N U Eman,F N U Gyaneshwari,Raveena Kumari et al.
F N U Eman et al.
Background: Colorectal cancer (CRC) is a major global health issue, with adenomatous polyps as the main precursors. Standard colonoscopy is the gold standard, but its effectiveness is limited by operator variability and m...
JAK Inhibitors for Crohn's Disease: A Systematic Review and Dose-Response Network Meta-Analysis of Efficacy and Safety [0.03%]
Janus激酶抑制剂治疗克罗恩病的疗效和安全性系统评价和剂量反应网络 meta 分析
Fares A Qtaishat,Ahmad AlKayyat,Jehad A Yasin et al.
Fares A Qtaishat et al.
Crohn's disease has limited effective treatments, and direct comparative data for Janus kinase (JAK) inhibitors are scarce. We conducted a dose-dependent network meta-analysis of randomized controlled trials in adults, searching PubMed, Coc...
Incidence of Cholangitis in Post-Endoscopic Retrograde Cholangiopancreatography (ERCP): A Systematic Review and Meta-Analysis [0.03%]
内镜逆行胰胆管造影术后胆管炎的发病率：系统回顾和 meta 分析
Shiwen Huang,Ying Huang,Feng Lu et al.
Shiwen Huang et al.
Background: Endoscopic retrograde cholangiopancreatography (ERCP) is a procedure that combines x-ray and upper gastrointestinal (GI) endoscopy for diagnosis and treatment of pancreatic and biliary diseases. Cholangitis is...
Validity and Reliability of the Caregiver Contribution to Self-Care of Chronic Illness Inventory in Patients With Inflammatory Bowel Disease [0.03%]
克罗恩病和溃疡性结肠炎照护者贡献于自我护理量表的信效度分析
Silvia Cilluffo,Davide Bartoli,Daniele Napolitano et al.
Silvia Cilluffo et al.
Aim: To assess the validity and reliability of the Caregiver Contribution to Self-Care of Chronic Illness Inventory (CC-SC-CII) among caregivers of patients with Inflammatory Bowel Disease (IBD). ...