Effect of Butyrate-Producing Enterobacteria and Proton Pump Inhibitors on Advanced Hepatocellular Carcinoma Treatment With Durvalumab and Tremelimumab [0.03%]
产生丁酸的肠杆菌和质子泵抑制剂对杜瓦鲁单抗和特莫普利姆аб治疗晚期肝细胞癌的影响
Kazuhiro Nouso,Akiko Wakuta,Shohei Shiota et al.
Kazuhiro Nouso et al.
Aim: The gut microbiome modulates immune responses, and butyrate-producing bacteria have been linked to improved immune checkpoint inhibitor (ICI) efficacy. Conversely, proton pump inhibitors (PPIs) may negatively impact ...
Eosinophilic Gastrointestinal Disease After Pediatric Organ and Bone Marrow Transplantation [0.03%]
儿童器官和骨髓移植后的嗜酸细胞性胃肠病
Erin Sinai,Bridget E Wilson,Melissa Pecak et al.
Erin Sinai et al.
Background: Previous studies have shown an increased prevalence of eosinophilic gastrointestinal disease (EGID) in pediatric liver and heart transplant recipients. However, EGID after other solid organ and bone marrow tra...
Impact of Gender and Race on Gastrointestinal Diseases in Patients With Parkinson's Disease: A Nationwide Analysis [0.03%]
帕金森病患者胃肠疾病的影响因素：全国范围的分析
Mohamed H Eldesouki,Ahmed Yasser Shaban,Mohamed Mahmoud Marey et al.
Mohamed H Eldesouki et al.
Background: Gastrointestinal (GI) diseases are common non-motor features of Parkinson's disease (PD), significantly impacting quality of life. The impact of racial and gender disparities in this population remains underex...
Sara Benterkia,Jenny Blythe
Sara Benterkia
Esophageal Perforation in Zollinger-Ellison Syndrome: A Scoping Review of Management and Outcomes [0.03%]
卓-艾综合征食管穿孔的管理与预后的系统综述
Agostino Fernicola,Domenico Parmeggiani,Felice Crocetto et al.
Agostino Fernicola et al.
Esophageal perforation in Zollinger-Ellison syndrome (ZES) is an exceedingly rare and life-threatening manifestation of gastrinoma-related acid hypersecretion. While peptic ulceration and severe reflux are recognized complications of ZES, p...
Pregnancy Outcomes and Disease Activity in Women With Inflammatory Bowel Disease in Qatar: A Retrospective Cohort Study [0.03%]
一项关于卡塔尔炎症性肠病女性妊娠结局和疾病活动性的回顾队列研究
Anwar I Joudah,Abdulwahab Hamid,Ayman Al-Dahshan et al.
Anwar I Joudah et al.
Background: Inflammatory bowel disease (IBD) commonly affects women of childbearing age and may complicate pregnancy. This study evaluated disease activity, treatment patterns, and pregnancy outcomes among women with IBD ...
Differentiation of Gallbladder Adenomyomatosis and Polyps in a Western Cohort: Prevalence, Ultrasound Characteristics, and Diagnostic Challenges [0.03%]
西方人群胆囊腺肌病和息肉的鉴别诊断：流行率、超声表现及诊断挑战
Marie Neumann,Michael Kallenbach,Ulrike Morgera et al.
Marie Neumann et al.
Background: Gallbladder adenomyomatosis and polyps are common benign lesions that can mimic malignancy on imaging, often leading to unnecessary cholecystectomy. Despite frequent sonographic detection, the prevalence of ad...
Anti-Tubercular Drug-Induced Liver Injury: Current Understanding and Emerging Directions [0.03%]
抗结核药性肝损伤：当前认知及未来方向
Shubham Prasad,Himanshu Narang,Saurabh Kedia et al.
Shubham Prasad et al.
Most common adverse effect causing cessation of anti-tubercular treatment (ATT) is drug-induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug-induced acute liver fa...
Dietary Characteristics Associated With High Defecation Frequency and Constipation in Japanese Adults: A Cross-Sectional Study [0.03%]
与高排便频率和便秘相关的日本成年人饮食特征：一项横断面研究
Hirokazu Taniguchi,Miho Ueda,Yukiko Kobayashi et al.
Hirokazu Taniguchi et al.
Aims: The aim of this study was to evaluate the association between defecation frequency and dietary characteristics in adult men and women to identify factors associated with appropriate defecation frequency. ...
Eosinophilic Esophagitis in the Middle East: Insight From a Comprehensive Systematic Review [0.03%]
来自全面系统回顾的关于中东地区嗜酸性粒细胞食管炎的见解
Nouran Alwisi,Sidra Abdul Moqeeth,Muneera Al-Mohannadi
Nouran Alwisi
Background: Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory disease of the esophagus, defined by esophageal dysfunction and dense eosinophilic infiltration (≥ 15 eosinophils per HPF) in biopsies...