Oral administration of the 11β-hydroxysteroid-dehydrogenase type 1 inhibitor RO5093151 to patients with glaucoma: an adaptive, randomised, placebo-controlled clinical study [0.03%]
一种选择性11β-羟基甾体脱氢酶型1抑制剂RO5093151的口服给药对青光眼患者房水和血浆中糖皮质激素的影响:一项自适应、随机、双盲、安慰剂对照临床研究
Dietmar Schwab,Carolina Sturm,Agnès Portron et al.
Dietmar Schwab et al.
Background/aims: Cortisol is involved in the regulation of intraocular pressure (IOP). This study aimed to assess the effect of 11β-hydroxysteroid-dehydrogenase type 1 (11βHSD1) inhibition by oral administration of RO50...
In vivo crystalline lens measurements with novel swept-source optical coherent tomography: an investigation on variability of measurement [0.03%]
新型扫频源光学相干层析在体测量人眼晶状体厚度的可重复性研究
Takuhei Shoji,Naoko Kato,Sho Ishikawa et al.
Takuhei Shoji et al.
Objective: To evaluate the reproducibility of in vivo crystalline lens measurements obtained by novel commercially available swept-source (SS) optical coherence tomography (OCT) specifically designed for anterior segment ...
Vitreoretinal interface abnormalities in middle-aged adults with visual impairment in the UK Biobank study: prevalence, impact on visual acuity and associations [0.03%]
英国生物样本库研究中视觉损伤的中年人视网膜界面异常的患病率、对视力的影响及联系:关联性研究
Martin McKibbin,Tracey Farragher,Darren Shickle
Martin McKibbin
Objective: The aim of this study was to determine the prevalence of vitreoretinal interface abnormalities (VRIA), the degree of visual impairment and associations with VRIA among adults, aged 40-69 years, in the UK Bioban...
Therapeutic potential of omega-3 fatty acids supplementation in a mouse model of dry macular degeneration [0.03%]
一种干性年龄相关性黄斑变性的鼠模型中ω-3脂肪酸补充的治疗潜力
Ekatherine Prokopiou,Panagiotis Kolovos,Maria Kalogerou et al.
Ekatherine Prokopiou et al.
Purpose: To evaluate the therapeutic effects of omega-3 (ω-3) and omega-6 (ω-6) fatty acids in the CCL2-/- model of dry age-related macular degeneration (AMD). The blood level of eicosapentaenoic acid (EPA) and arachido...
Pre-eclampsia and the risk of retinopathy of prematurity in preterm infants with birth weight <1500 g and/or <31 weeks' gestation [0.03%]
子痫前期与极低体重儿视网膜病的发病风险关系研究
Belal Alshaikh,Omar Salman,Nancy Soliman et al.
Belal Alshaikh et al.
Objective: To evaluate the relationship between pre-eclampsia and development of retinopathy of prematurity (ROP) in infants with birth weight of
Physical inactivity in relation to self-rated eyesight: cross-sectional analysis from the English Longitudinal Study of Ageing [0.03%]
基于英格兰老龄化纵向研究的眼视力自我评价与身体活动不足的关系的横断面分析
Lee Smith,Matthew A Timmis,Shahina Pardhan et al.
Lee Smith et al.
Background: To assess the cross-sectional association between self-rated eyesight and physical activity behaviour in a large general population sample of older English adults. ...
Chameen Samarawickrama,Yi-Chiao Li,Nicole Carnt et al.
Chameen Samarawickrama et al.
Aims: To identify potential contaminants of the corneal sampling procedure and examine the effect of wearing surgical face masks on the rate of contamination. ...
Retinal embolic events: frequency and impact following transcatheter aortic valve implantation (TAVI) for aortic stenosis [0.03%]
经导管主动脉瓣植入术(TAVI)后视网膜栓塞事件的发生率和影响:治疗主动脉瓣狭窄的一项研究
William J Fusi-Rubiano,Yit C Yang,Andrew F Smallwood et al.
William J Fusi-Rubiano et al.
Objectives: Transcatheter aortic valve implantation (TAVI) is an established treatment for patients with severe symptomatic aortic stenosis. It has a cerebrovascular accident rate of about 5% but the effect on retinal emb...
Karen K W Chan,Fangyao Tang,Clement C Y Tham et al.
Karen K W Chan et al.
Despite the critical impact of glaucoma on global blindness, its aetiology is not fully characterised. Elevated intraocular pressure is highly associated with glaucomatous optic neuropathy. However, visual field loss still progresses in som...
Disposable versus non-disposable tonometer prisms: a UK national survey [0.03%]
关于英国单次性与重复使用型压平式眼压计测量头的全国调查
Kirti M Jasani,Christine Putri,Amy Pearl et al.
Kirti M Jasani et al.
Purpose: To determine the prevalence of disposable tonometer versus non-disposable tonometer use in the UK and to determine methods of decontamination and frequency of replacement of prisms.A total of 137 ophthalmology de...