Expert recommendations for the management of fecal incontinence in systemic sclerosis: A report from the World Scleroderma Foundation (WSF) Gastrointestinal "Ad hoc committee" [0.03%]
系统性硬化症管理大便失禁的专家建议：世界硬化症基金会（WSF）胃肠“特别工作组”的报告
Zsuzsanna H McMahan,Maria Cristina De Santis,Anna Lo Cricchio et al.
Zsuzsanna H McMahan et al.
Background: Fecal incontinence (FI) affects up to 50% of patients with systemic sclerosis (SSc), significantly impairing quality of life and daily functioning. Despite its prevalence, patients may not disclose their sympt...
Expert recommendations for the management of refractory gastroesophageal reflux disease in systemic sclerosis: A report from the World Scleroderma Foundation (WSF) Gastrointestinal "Ad hoc committee" [0.03%]
顽固性胃食管反流病的系统性硬化症患者管理专家建议：世界系统性硬化症基金会胃肠“特别工作组”报告
Michael Hughes,Anna Lo Cricchio,Maria Cristina De Santis et al.
Michael Hughes et al.
Background: Gastro-esophageal reflux disease (GERD) occurs in most (~75%) patients with systemic sclerosis (SSc) and significantly impacts quality of life. Current recommendations lack depth and therefore, our aim was to ...
Predictor factors of successful treatment response in interstitial lung disease-related systemic sclerosis [0.03%]
特发性肺纤维化相关系统硬化症成功治疗反应的预测因素分析
Gantira Wijayakusumah Danasasmita,Suryo Anggoro Kusumo Wibowo,Cleopas Martin Rumende et al.
Gantira Wijayakusumah Danasasmita et al.
Background: Systemic sclerosis (SSc) is a multi-organ autoimmune disease presenting interstitial lung disease (ILD) as the most common internal organ manifestation as it can be found in 25-90% of radiological imaging even...
Influence of comorbidities and patient demographics on Raynaud's symptom characteristics: implications for diagnosis and management [0.03%]
共病和患者的人口统计学特征对雷诺氏症症状的影响：对诊断和治疗的启示
Reshma Seomore,Matthew Wells,Ula Tymoszuk et al.
Reshma Seomore et al.
Objectives: Associations between Raynaud's phenomenon (RP) and body mass index (BMI), fibromyalgia syndrome (FMS) and migraine have been reported but their influence on the lived experience of RP is unknown. ...
Knowledge and perceptions of medical practitioners on the role of nutrition in systemic sclerosis [0.03%]
医务人员对营养在系统性硬化病中作用的知识和认识
Elisavet Efthymiou,Eleni C Pardali,Arriana Gkouvi et al.
Elisavet Efthymiou et al.
Objectives: Systemic sclerosis (SSc) presents complex manifestations that impact disease progression and quality of life. Despite the burden of gastrointestinal (GI) and nutrition-related symptoms, a lack of consensus is ...
Scleroderma Clinical Trials Consortium (SCTC) outcome instruments for evaluation of systemic sclerosis [0.03%]
系统性硬化症评估的硬皮病临床试验联盟（SCTC）评估工具
Antonia Valenzuela,Lorinda Chung,John D Pauling et al.
Antonia Valenzuela et al.
The Scleroderma Clinical Trials Consortium (SCTC) is committed to advancing the understanding and treatment of systemic sclerosis (SSc). This review focuses on the development and validation of various outcome instruments by the SCTC, which...
Palliative care in systemic sclerosis: incorporating advance care planning into longitudinal care [0.03%]
系统性硬化症的姑息治疗：在长期治疗中加入预前照护计划
Marissa B Savoie,Jessica L Logeman,Flavia V Castelino
Marissa B Savoie
Despite advances in rheumatological treatments, patients with systemic sclerosis (SSc) suffer with myriad symptoms and experience associated quality of life decrements. Although SSc-related mortality is reported around 53%, there is a pauci...
What is the treatment pattern of juvenile systemic sclerosis? Results from an international cohort [0.03%]
儿童系统性硬化症的治疗模式是什么？来自国际队列的结果
Ivan Foeldvari,Kathryn Torok,Ozgur Kasapcopur et al.
Ivan Foeldvari et al.
Objectives: Clinical trial data are lacking for treatment of patients with juvenile systemic sclerosis (jSSc). Three published recommendations exist for jSSc but real-world data on treatment patterns are lacking. The aim ...
Are we ready to predict progressive disease in juvenile systemic sclerosis? [0.03%]
我们能够预测儿童系统性硬化症的进展吗？
Ivan Foeldvari,Jens Klotsche,Kathryn S Torok
Ivan Foeldvari
AhR agonist Ficz modulates T follicular helper cells and ameliorates skin fibrosis in a bleomycin-induced SSc mouse model [0.03%]
表皮AhR激动剂Ficz改善系统性硬化病动物模型中的皮肤纤维化
Xianzhong Zhu,Yulin Chen,Chuangye Qiu et al.
Xianzhong Zhu et al.
Objectives: T follicular helper (Tfh) cells are involved in the pathogenesis of systemic sclerosis (SSc). Recent investigations have revealed aryl hydrocarbon receptor (AhR) regulated skin fibrosis in SSc. This study aims...