Donor-specific digital twin for living donor liver transplant recovery [0.03%]
供体特异性数字孪生在活体肝移植术后恢复中的应用
Suvankar Halder,Michael C Lawrence,Giuliano Testa et al.
Suvankar Halder et al.
The remarkable capacity of the liver to regenerate its lost mass after resection makes living donor liver transplantation a successful treatment option. However, donor heterogeneity significantly influences recovery trajectories, highlighti...
Integrating support vector machines and deep learning features for oral cancer histopathology analysis [0.03%]
支持向量机和深度学习特征在口腔癌病理分析中的融合应用研究
Tuan D Pham
Tuan D Pham
This study introduces an approach to classifying histopathological images for detecting dysplasia in oral cancer through the fusion of support vector machine (SVM) classifiers trained on deep learning features extracted from InceptionResNet...
Optimizing drug synergy prediction through categorical embeddings in deep neural networks [0.03%]
深度神经网络中通过分类嵌入优化药物协同效应预测
Manuel González Lastre,Pablo González De Prado Salas,Raúl Guantes
Manuel González Lastre
Cancer treatments often lose effectiveness as tumors develop resistance to single-agent therapies. Combination treatments can overcome this limitation, but the overwhelming combinatorial space of drug-dose interactions makes exhaustive expe...
AutoRadAI: a versatile artificial intelligence framework validated for detecting extracapsular extension in prostate cancer [0.03%]
AutoRadAI：一种经过验证可检测前列腺癌囊外浸润的灵活的人工智能框架
Pegah Khosravi,Shady Saikali,Abolfazl Alipour et al.
Pegah Khosravi et al.
Preoperative identification of extracapsular extension (ECE) in prostate cancer (PCa) is crucial for effective treatment planning, as ECE presence significantly increases the risk of positive surgical margins and early biochemical recurrenc...
A deep learning pipeline for morphological and viability assessment of 3D cancer cell spheroids [0.03%]
一种用于三维癌细胞球体形态和活力评估的深度学习流水线
Ajay K Mali,Sivasubramanian Murugappan,Jayashree Rajesh Prasad et al.
Ajay K Mali et al.
Three-dimensional (3D) spheroid models have advanced cancer research by better mimicking the tumour microenvironment compared to traditional two-dimensional cell cultures. However, challenges persist in high-throughput analysis of morpholog...
Navigating the Multiverse: a Hitchhiker's guide to selecting harmonization methods for multimodal biomedical data [0.03%]
穿梭多元宇宙：生物医学多模态数据 harmonization 方法选择指南
Murali Aadhitya Magateshvaren Saras,Mithun K Mitra,Sonika Tyagi
Murali Aadhitya Magateshvaren Saras
The application of machine learning (ML) techniques in predictive modelling has greatly advanced our comprehension of biological systems. There is a notable shift in the trend towards integration methods that specifically target the simulta...
Development of a sperm morphology assessment standardization training tool [0.03%]
一种精子形态评估标准化培训工具的开发
Katherine R Seymour,Jessica P Rickard,Kelsey R Pool et al.
Katherine R Seymour et al.
Training to improve the standardization of subjective assessments in biological science is crucial to improve and maintain accuracy. However, in reproductive science there is no standardized training tool available to assess sperm morpholog...
Quantitative tools for analyzing rhizosphere pH dynamics: localized and integrated approaches [0.03%]
分析根际pH动态的定量工具：局部和整体方法
Poonam Kanwar,Stan Altmeisch,Petra Bauer
Poonam Kanwar
The rhizosphere, the region surrounding plant roots, plays a critical role in nutrient acquisition, root development, and plant-soil interactions. Spatial variations in rhizosphere pH along the root axis are shaped by environmental cues, nu...
Optimized immunofluorescence for liver structure analysis: Enhancing 3D resolution and minimizing tissue autofluorescence [0.03%]
优化的免疫荧光技术用于肝脏结构分析：提高三维分辨率和减少组织自发荧光
Elena Zoppolato,Hasse Mol,Carlos Estrella-García et al.
Elena Zoppolato et al.
The study of liver biology and pathology through marker expression analysis and tissue structure visualization is constrained by the high autofluorescence caused by the presence of lipofuscins, vitamin A, and lipid droplets, which tradition...
Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy [0.03%]
一种足细胞病动物模型的数字病理学评估肾小球滤过屏障超微结构
Aksel Laudon,Zhaoze Wang,Anqi Zou et al.
Aksel Laudon et al.
Transmission electron microscopy (TEM) images can visualize kidney glomerular filtration barrier ultrastructure, including the glomerular basement membrane (GBM) and podocyte foot processes (PFP). Podocytopathy is associated with glomerular...