LAMPrey: a standardised method for analysing quantitative LAMP reactions using the inflection cycle threshold [0.03%]
基于拐点阈值的定量LAMP反应分析的标准方法LAMPrey
Adam Bates,Jiao Li,Sofia Vamos et al.
Adam Bates et al.
Quantitative loop-mediated isothermal amplification (qLAMP) is a gene expression quantification method that has gained popularity in recent years, particularly in disease identification, including during the recent SARS-CoV-2 pandemic. Unli...
Marwa M Ali,Inas J Mahdi,Hayder Obayes Hashim et al.
Marwa M Ali et al.
Tryptophanase (TnaA; EC 4.1.99.1) is a pyridoxal 5'-phosphate-dependent enzyme that catalyzes the β-elimination of L-tryptophan into indole, pyruvate, and ammonia. It plays a key role in bacterial signaling and biofilm formation and is ind...
A multi-dimensional CNN-Bi-GRU for IoT-based brain-computer interface in early epileptic seizure detection [0.03%]
一种基于CNN-Bi-GRU的多维卷积神经网络及在基于物联网的脑机接口中的应用
Biplov Paneru
Biplov Paneru
The study focuses on seizure detection using EEG data from Mendeley. An early-alert IoT-BCI system is designed to simulate real-time support for patients during seizures. The proposed Multi-Dimensional CNN-Bi-GRU (MDCBG) outperforms hybrid ...
Enhancing propagation and purification efficiency of M13 bacteriophage for improved phage display applications [0.03%]
提高M13噬菌体传播和纯化效率以改进噬菌体展示应用
Md Monir Hossain,Foong Yong,Vipul Bansal et al.
Md Monir Hossain et al.
The global biosensors market is rapidly growing, driven by increasing demand for quick, affordable, and portable diagnostic tools across sectors, including healthcare, environmental monitoring, food safety, and biomedical research. The key ...
UniClo technology exploits methylation for universal scarless DNA assembly [0.03%]
利用甲基化进行通用无痕DNA组装的UniClo技术
Carol N Flores-Fernández,Da Lin,Katherine Robins et al.
Carol N Flores-Fernández et al.
Several Golden Gate-based DNA assembly techniques have been developed previously with different limitations including the requirement for domestication of sequences with internal sites for the type IIS restriction enzymes used, insertion of...
One size does not fit all: A comparative framework for optimizing ribonucleic acid transfection across acute myeloid leukemia cell lines [0.03%]
大小不通吃：一种用于优化急性髓系白血病细胞系中的核糖核酸转染的比较框架
Monika M Kojic,Carmen Spencer,Olivia Kovecses et al.
Monika M Kojic et al.
Robust transient knockdown strategies are critical to oligonucleotide therapeutic development, yet ineffective and variable RNA delivery across experimental models continues to limit target validation. Efficient delivery of nucleic acids in...
Investigating the association of NBN gene polymorphisms with multiple cancers through statistical meta-analysis and bioinformatics insights [0.03%]
基于统计学meta分析和生物信息学洞察研究NBN基因多态性与多种癌症的关联性
Md Harun-Or-Roshid,Md Selim Reza,Md Ariful Islam et al.
Md Harun-Or-Roshid et al.
Several individual genetic association studies, including meta-analyses, have investigated the association of two SNPs (rs1805794 and rs709816) of NBN gene with multiple cancer risks. However, their findings were inconsistent, making it cha...
Large language model-based multiagent collaboration for abstract screening toward automated systematic reviews [0.03%]
基于大型语言模型的摘要筛选多智能体协作以实现自动系统评价
Opeoluwa Akinseloyin,Xiaorui Jiang,Vasile Palade
Opeoluwa Akinseloyin
Systematic reviews (SRs) are essential for evidence-based practice but remain labor-intensive, especially during abstract screening. This study evaluates whether multiple large language models (multi-LLMs) collaboration can improve the effi...
Linking patient records at scale with a hybrid approach combining contrastive learning and deterministic rules [0.03%]
结合对比学习和确定性规则的大规模患者记录链接方法
Cheng Cao,Jay Pillai,Sara Daraei et al.
Cheng Cao et al.
Linking patient records across disparate healthcare systems is essential to create comprehensive views of patient health, yet this task is complicated by inconsistent identifiers and data quality issues. Although traditional deterministic a...
Enhanced formulation of precision probiotics through active machine learning [0.03%]
通过主动机器学习增强精准益生菌配方
Anweshit Panda,Manaswani Adhikari,Sourya Subhra Nasker et al.
Anweshit Panda et al.
The human gut microbiome is crucial to health, with dysbiosis increasingly linked to disease. Precision probiotics offer a promising approach to restoring microbial balance, but ensuring probiotic viability through gastrointestinal transit ...