Sustained-release local anesthetics: advances in drug delivery systems for prolonged postoperative analgesia [0.03%]
长效局部麻醉药：术后长效镇痛药物输送系统的进展
Seok Kyeong Oh,Sang Hyun Hong,Jung-Woo Shim
Seok Kyeong Oh
Effective perioperative pain control is essential for patient comfort and for optimizing surgical outcomes and the quality of recovery. Multimodal analgesic strategies have become a cornerstone of modern perioperative pain management. Altho...
The clinical evidence and strategic use of hyaluronidase in spinal interventions [0.03%]
玻璃酸酶在脊柱干预中的临床证据和战略应用
Jae Hun Kim
Jae Hun Kim
Hyaluronidase is an enzyme that degrades hyaluronic acid within the extracellular matrix, thereby increasing tissue permeability and facilitating the dispersion of injected agents. Hyaluronidase has been used as an adjunct in spinal interve...
Hye-Mi Lee,Young Sung Kim,Eun-Hee Kim et al.
Hye-Mi Lee et al.
Safe and effective pediatric sedation depends on multiple factors, including the precise selection of sedative agents, provider expertise, availability of age-appropriate monitoring equipment, and the patients' individual circumstances. The...
Hyo-Jin Byon
Hyo-Jin Byon
Epigenetics, the study of heritable changes in gene expression that occur without altering the underlying DNA sequence, has emerged as an important conceptual framework for anesthesiology. The epigenome is organized into three mechanistic t...
Prophylactic infusion of norepinephrine enhances hemodynamic stability during propofol induction and early intubation period in elderly patients: a double-blind randomized placebo-controlled trial [0.03%]
预防性输注去甲肾上腺素可提高老年患者丙泊酚诱导及早期插管期的循环稳定性：一项双盲随机安慰剂对照试验
Wenping Peng,Xiaolu Sun,Shuang Zhao et al.
Wenping Peng et al.
Background: The induction of general anesthesia with propofol often results in hypotension, which is primarily attributed to a decrease in the cardiac index (CI) among elderly patients. Norepinephrine (NE) is typically us...
Efficacy and safety of sugammadex for reversal of neuromuscular blockade in pediatric patients: an updated systematic review and meta-analysis of randomized controlled trials with trial sequential analysis [0.03%]
Sugammadex用于儿科患者神经肌肉阻滞逆转的有效性和安全性：随机对照试验的更新系统评价和meta分析及序贯试验分析
Hyosung Kim,Byung Gun Lim,Young Sung Kim et al.
Hyosung Kim et al.
Background: Sugammadex has recently been approved globally for use in pediatric patients aged ≥ 2 years. This meta-analysis with trial sequential analysis (TSA) evaluated the efficacy and safety of sugammadex for reversa...
Suspected remimazolam formulation-associated peri-induction anaphylaxis: two cases highlighting diagnostic complexity - Two case reports [0.03%]
瑞玛唑仑相关诱导期过敏性休克的两例报道及诊断难点分析
Hyun-Seong Lee,Min Woo Lee,Daeseok Oh
Hyun-Seong Lee
Background: Reports of remimazolam formulation-associated anaphylaxis are increasing as its use expands. Between 2023 and 2025, we identified two severe reactions among 1,592 patients who received remimazolam at our insti...
From visibility to influence [0.03%]
从能见度到影响力
Min Kyoung Kim,Hyun Kang
Min Kyoung Kim
Obstetric anesthesia and postpartum mental health: implications from delivery to long-term recovery [0.03%]
从分娩到长期恢复的产科麻醉和产后精神健康：对未来研究的影响
Sou-Hyun Lee,Kyung-Hwa Kwak
Sou-Hyun Lee
Obstetric anesthesiologists have traditionally focused on providing effective labor analgesia and ensuring safe cesarean delivery. However, growing evidence suggests that anesthetic choices and childbirth experiences influence maternal ment...