Miao Cao,Michael Xu,Zinah Bairmani et al.
Miao Cao et al.
Introduction: Colorectal cancer (CRC) is the fourth most common cancer and second leading cause of cancer-related death in the United States. The implementation of CRC screening has decreased CRC incidence in adults older...
Advances in the field of developing biomarkers for re-irradiation: a how-to guide to small, powerful data sets and artificial intelligence [0.03%]
生物标志物开发领域的进展：小而强大的数据集和人工智能的应用指南
Chaudhry Huma,Lee Hawon,Jagasia Sarisha et al.
Chaudhry Huma et al.
Introduction: Patient selection remains challenging as the clinical use of re-irradiation (re-RT) increases. Re-RT data is limited to retrospective studies and small prospective single-institution reports, resulting in sm...
Identifying patients suitable for targeted adjuvant therapy: advances in the field of developing biomarkers for tumor recurrence following irradiation [0.03%]
识别适合靶向辅助治疗的患者：放射后肿瘤复发生物标志物开发领域的新进展
S Jagasia,E Tasci,Ying Zhuge et al.
S Jagasia et al.
Introduction: Radiation therapy (RT) is commonly used to treat cancer in conjunction with chemotherapy, immunotherapy, and targeted therapies. Despite the effectiveness of RT, tumor recurrence due to treatment resistance ...
Jane A Leopold
Jane A Leopold
Introduction: Cardiovascular disease persists as the leading cause of death worldwide despite continued advances in diagnostics and therapeutics. Our current approach to patients with cardiovascular disease is rooted in r...
Novel insights into the pathogenesis and treatment of NRAS mutant melanoma [0.03%]
NRAS突变型黑色素瘤的发病机制及治疗新见解
Jeffrey Zhao,Carlos Galvez,Kathryn Eby Beckermann et al.
Jeffrey Zhao et al.
Introduction: NRAS was the first mutated oncogene identified in melanoma and is currently the second most common driver mutation in this malignancy. For patients with NRASmutant advanced stage melanoma refractory to immun...
The Use of Blood Biomarkers in Precision Medicine for the Primary Prevention of Atherosclerotic Cardiovascular Disease: a Review [0.03%]
用于动脉粥样硬化性心血管疾病初发事件精准预防的血液生物标志物的研究进展：综述文章
Ty Sweeney,Renato Quispe,Thomas Das et al.
Ty Sweeney et al.
Introduction: A biomarker is a substance, structure, or process that indicates the presence of a disease, infection, or environmental exposure. Clinically useful biomarkers are measurable, improve diagnostic or prognostic...
Proteomics-inspired precision medicine for treating and understanding multiple myeloma [0.03%]
基于蛋白质组学的精准医学在治疗和研究多发性骨髓瘤中的应用
Matthew Ho,Giada Bianchi,Kenneth C Anderson
Matthew Ho
Introduction: Remarkable progress in molecular characterization methods has led to significant improvements in how we manage multiple myeloma (MM). The introduction of novel therapies has led to significant improvements i...
On the path towards personalized medicine: Implications of pharmacogenetic studies of alcohol use disorder medications [0.03%]
个体化医疗之路：酒精使用障碍药物药理遗传学研究的影响
Steven J Nieto,Erica N Grodin,Lara A Ray
Steven J Nieto
Introduction: The heritability of alcohol use disorder (AUD) is estimated to be ~50%; however, the genetic basis of the disease is still poorly understood. The genetic variants identified thus far only explain a small per...
Clinical application of personalized rheumatoid arthritis risk information: Translational epidemiology leading to precision medicine [0.03%]
个性化类风湿性关节炎风险信息的临床应用：从转化流行病学到精准医疗
Jeffrey A Sparks
Jeffrey A Sparks
GUCY2C as a biomarker to target precision therapies for patients with colorectal cancer [0.03%]
GUCY2C作为结直肠癌精确诊疗的生物标志物及其靶向免疫治疗研究
Amanda N Lisby,John C Flickinger Jr,Babar Bashir et al.
Amanda N Lisby et al.
Introduction: Colorectal cancer (CRC) is one of the most-deadly malignancies worldwide. Current therapeutic regimens for CRC patients are relatively generic, based primarily on disease type and stage, with little variatio...