Manipulation of the dually thermoresponsive behavior of peptide-based vesicles through modification of collagen-like peptide domains [0.03%]
通过修饰胶原样肽区段操纵基于肽的囊泡的双重热响应行为
Lucas C Dunshee,Millicent O Sullivan,Kristi L Kiick
Lucas C Dunshee
Materials that respond to temporally defined exogenous cues continue to be an active pursuit of research toward on-demand nanoparticle drug delivery applications, and using one or more exogenous temperature stimuli could significantly expan...
Krystina L Hess,Christopher M Jewell
Krystina L Hess
Bacteriophages, or phages, are viruses that specifically infect bacteria and coopt the cellular machinery to create more phage proteins, eventually resulting in the release of new phage particles. Phages are heavily utilized in bioengineeri...
Aaron C Anselmo
Aaron C Anselmo
Aaron C Anselmo,Samir Mitragotri
Aaron C Anselmo
Nanoparticle drug delivery systems have been used in the clinic since the early 1990's. Since that time, the field of nanomedicine has evolved alongside growing technological needs to improve the delivery of various therapeutics. Over these...
Editorial: The launch phase of Bioengineering & Translational Medicine [0.03%]
编者按：Bioengineering与Translational Medicine创刊词
Samir Mitragotri
Samir Mitragotri
Lauren A Herron,Corey S Hansen,Hasan E Abaci
Lauren A Herron
Vascular diversity among organs has recently become widely recognized. Several studies using mouse and human fetal tissues revealed distinct characteristics of organ-specific vasculature in molecular and functional levels. Thorough understa...
Leader cell PLCγ1 activation during keratinocyte collective migration is induced by EGFR localization and clustering [0.03%]
领导细胞PLCγ1活化在角质形成细胞集体迁移过程中由EGFR定位和聚簇所诱导
Chloe S Kim,Xinhai Yang,Sarah Jacobsen et al.
Chloe S Kim et al.
Re-epithelialization is a critical step in wound healing and results from the collective migration of keratinocytes. Previous work demonstrated that immobilized, but not soluble, epidermal growth factor (EGF) resulted in leader cell-specifi...
Understanding optical reflectance contrast for real-time characterization of epithelial precursor lesions [0.03%]
光学反射对比度在表皮癌前病变实时特征分析中的作用理解
Si Chen,Xin Ge,Xinyu Liu et al.
Si Chen et al.
Detecting early-stage epithelial cancers and their precursor lesions are challenging as lesions could be subtle and focally or heterogeneously distributed over large mucosal areas. Optical coherence tomography (OCT) that enables wide-field ...
Facilitating plasmid nuclear delivery by interfering with the selective nuclear pore barrier [0.03%]
通过干扰选择性核孔屏障促进质粒的核内递送
Ihab Azzam,Ivan Liashkovich,Isabelle Luchtefeld et al.
Ihab Azzam et al.
Nuclear pore complexes (NPCs) are sophisticated transporters assembled from diverse proteins termed nucleoporins (Nups). They control all nucleocytoplasmic transport and form a stringent barrier between the cytosol and the nucleus. While se...
Aaron C Anselmo
Aaron C Anselmo