Validation of the 1,4-butanediol thermoplastic polyurethane as a novel material for 3D bioprinting applications [0.03%]
1,4-丁二醇热塑性聚氨酯作为3D生物打印应用新材料的验证研究
Carlos Chocarro-Wrona,Juan de Vicente,Cristina Antich et al.
Carlos Chocarro-Wrona et al.
Tissue engineering (TE) seeks to fabricate implants that mimic the mechanical strength, structure, and composition of native tissues. Cartilage TE requires the development of functional personalized implants with cartilage-like mechanical p...
Magnetic microgels and nanogels: Physical mechanisms and biomedical applications [0.03%]
磁性微凝胶和纳凝胶：物理机制与生物医学应用
Baeckkyoung Sung,Min-Ho Kim,Leon Abelmann
Baeckkyoung Sung
Soft micro- and nanostructures have been extensively developed for biomedical applications. The main focus has been on multifunctional composite materials that combine the advantages of hydrogels and colloidal particles. Magnetic microgels ...
Ultrasound-microbubble cavitation facilitates adeno-associated virus mediated cochlear gene transfection across the round-window membrane [0.03%]
通过圆窗膜介导的腺相关病毒载体耳蜗基因转染的小气泡超声空化效应研究
Zhen Zhang,Zhengnong Chen,Liqiang Fan et al.
Zhen Zhang et al.
The round window of the cochlea provides an ideal route for delivering medicines and gene therapy reagents that can cross the round window membrane (RWM) into the inner ear. Recombinant adeno-associated viruses (rAAVs) have several advantag...
Gemcitabine and doxorubicin in immunostimulatory monophosphoryl lipid A liposomes for treating breast cancer [0.03%]
免疫刺激单磷酸脂质A脂质体包裹吉西他滨和阿霉素治疗乳腺癌
Debra Wu,Zongmin Zhao,Jayoung Kim et al.
Debra Wu et al.
Cancer therapy is increasingly shifting toward targeting the tumor immune microenvironment and influencing populations of tumor infiltrating lymphocytes. Breast cancer presents a unique challenge as tumors of the triple-negative breast canc...
Cartilage-targeting ultrasmall lipid-polymer hybrid nanoparticles for the prevention of cartilage degradation [0.03%]
靶向软骨的超小型脂质-聚合物混合纳米颗粒用于防治软骨降解
Xiangzhao Ai,Yaou Duan,Qiangzhe Zhang et al.
Xiangzhao Ai et al.
Current drug delivery approaches for the treatment of cartilage disorders such as osteoarthritis (OA) remain inadequate to achieve sufficient drug penetration and retention in the dense cartilage matrix. Herein, we synthesize sub-30 nm lipi...
The secretome of stressed peripheral blood mononuclear cells increases tissue survival in a rodent epigastric flap model [0.03%]
应激外周血单个核细胞的分泌组可增加 rodents 部门腹壁皮瓣的组织存活率
Stefan Hacker,Rainer Mittermayr,Denise Traxler et al.
Stefan Hacker et al.
Reconstructive surgery transfers viable tissue to cover defects and to restore aesthetic and functional properties. Failure rates after free flap surgery range from 3 to 7%. Co-morbidities such as diabetes mellitus or peripheral vascular di...
Current status of targeted microbubbles in diagnostic molecular imaging of pancreatic cancer [0.03%]
靶向微气泡在胰腺癌诊断分子影像中的研究进展及现状分析
Natacha Jugniot,Rakesh Bam,Emmanuelle J Meuillet et al.
Natacha Jugniot et al.
Pancreatic ductal adenocarcinoma (PDAC) is often associated with a poor prognosis due to silent onset, resistance to therapies, and rapid spreading. Most patients are ineligible for curable surgery as they present with advanced disease at t...
Resection and survival data from a clinical trial of glioblastoma multiforme-specific IRDye800-BBN fluorescence-guided surgery [0.03%]
胶质母细胞瘤特异性IRdye800-BBN荧光引导手术的切除和生存数据临床试验结果
Kunshan He,Chongwei Chi,Deling Li et al.
Kunshan He et al.
Supra-maximum surgical tumor resection without neurological damage is highly valuable for treatment and prognosis of patients with glioblastoma multiforme (GBM). We developed a GBM-specific fluorescence probe using IRDye800CW (peak absorpti...
A novel bilayered expanded polytetrafluoroethylene glaucoma implant creates a permeable thin capsule independent of aqueous humor exposure [0.03%]
一种新型双层结构的眼用膨体四氟乙烯青光眼引流装置能够形成与房水接触与否无关的可渗透性薄囊包裹
Amanda Kiely Bicket,Julia Szeto,Peter Roeber et al.
Amanda Kiely Bicket et al.
The purpose of these studies was to evaluate clinical, functional, and histopathological features of glaucoma drainage implants (GDIs) fabricated from novel, custom-tailored expanded polytetrafluoroethylene (ePTFE). Implants of matching foo...
Point-of-care semen analysis of patients with infertility via smartphone and colorimetric paper-based diagnostic device [0.03%]
基于智能手机和比色纸的诊断设备的男科无实验室精液分析检测应用于不育患者的初步研究
Yu-Ting Tsao,Chung-Yao Yang,Yun-Chiao Wen et al.
Yu-Ting Tsao et al.
Male infertility affects millions of males worldwide and is rising in prevalence due to social and environmental conditions. However, men often feel too embarrassed to receive a semen analysis in the hospital due to social stigmas. To overc...