The hanging-heart chip: A portable microfluidic device for high-throughput generation of contractile embryonic stem cell-derived cardiac spheroids [0.03%]
心形芯片：一种便携式微流控设备，可大批量产生收缩型胚胎干细胞来源的心脏球体
Pei-Tzu Lai,Cheng-Kun He,Chi-Han Li et al.
Pei-Tzu Lai et al.
Stem cell-derived cardiac spheroids are promising models for cardiac research and drug testing. However, generating contracting cardiac spheroids remains challenging because of the laborious experimental procedure. Here, we present a microf...
A non-surgical method for subretinal delivery by trans-scleral microneedle injection [0.03%]
一种通过微针经巩膜非手术给药的方法
Amir Hejri,Micah A Chrenek,Nolan T Goehring et al.
Amir Hejri et al.
Novel therapeutics have emerged for treating neurodegenerative eye diseases but are limited by non-optimal methods of ocular administration. Subretinal injection is the preferred method of delivery for retinal gene and stem-cell therapies, ...
Establishment of a chemoresistant laryngeal cancer cell model to study chemoresistance and chemosensitization responses via transcriptomic analysis and a tumor-on-a-chip platform [0.03%]
基于转录组分析和类器官芯片平台的喉癌化疗耐药细胞模型的建立及相关机制研究
Christian R Moya-Garcia,Meghana Munipalle,Alain Pacis et al.
Christian R Moya-Garcia et al.
Tumor resistance to chemotherapy is a common cause of cancer recurrence in patients with head and neck squamous cell carcinoma. The goal of this study is to establish and characterize a chemoresistant laryngeal cancer cell model and test it...
Amelioration of biased neuronal differentiation in humanized mouse model of valproic acid-induced autism by precisely targeted transcranial magnetic stimulation [0.03%]
经颅磁刺激改善丙戊酸致自闭症小鼠模型的偏向性神经分化异常
Yilin Hou,Youyi Zhao,Dingding Yang et al.
Yilin Hou et al.
Autism spectrum disorder (ASD) is a group of developmental diseases, which still lacks effective treatments. Pregnant exposure of Valproic acid (VPA) is an important environmental risk factor for ASD, but it's long-term effects on the devel...
Correction to "Drug cross-linking electrospun fiber for effective infected wound healing" [0.03%]
关于“用于有效感染伤口愈合的药物交联电纺纤维”的更正
[This corrects the article DOI: 10.1002/btm2.10540.]. © 2025 The Author(s). Bioengineering & Translational Medicine published by Wiley Periodicals LLC o...
Published Erratum
Bioengineering & translational medicine. 2025 Mar 17;10(3):e10758. DOI:10.1002/btm2.10758 2025
The potential of low-intensity pulsed ultrasound to apply the long-term ovary protection from injury induced by 4-vinylcyclohexene diepoxide through inhibiting granulosa cell apoptosis [0.03%]
低强度脉冲超声通过抑制颗粒细胞凋亡抑制4-乙烯基环己烯二氧诱导的卵巢损伤并提供长期卵巢保护的潜力
Juan Deng,Juan Qin,Guolin Song et al.
Juan Deng et al.
The potential of low-intensity pulsed ultrasound (LIPUS) in regulating ovarian function has been demonstrated; however, there is a lack of scientific evidence regarding the long-term efficacy of LIPUS in treating ovarian injury and understa...
AI-assisted warfarin dose optimisation with CURATE.AI for clinical impact: Retrospective data analysis [0.03%]
CURATE.AI辅助的人工智能华法林剂量优化对临床影响的回顾性数据分析
Tiffany Rui Xuan Gan,Lester W J Tan,Mathias Egermark et al.
Tiffany Rui Xuan Gan et al.
Background: Standard-of-care for warfarin dose titration is conventionally based on physician-guided drug dosing. This may lead to frequent deviations from target international normalized ratio (INR) due to inter- and int...
An in-cell helicase reporter system for quantifying DDX3X and DDX3Y activities [0.03%]
一种用于定量DDX3X和DDX3Y活性的细胞内解旋酶报告系统
Zhi Sheng Poh,James Chia Wei Tan,Brandon Han Siang Wong et al.
Zhi Sheng Poh et al.
Genome sequencing has identified numerous mutations in the DEAD-box RNA helicases, DDX3X and DDX3Y, associated with cancer and other diseases, but monitoring of their functional consequences remains a challenge. Conventional helicase assays...
The BAM-GelMA-ADSCs bilayer patch promotes tissue regeneration and functional recovery after large-area bladder defects in beagles [0.03%]
BAM-GelMA-ADSCs双层补片促进比格犬大范围膀胱缺损的组织再生和功能恢复
Ziyan An,Pengchao Wang,Zhengyun Ling et al.
Ziyan An et al.
Previous studies of bladder tissue engineering simply seeded cells onto the surface of the material, which makes the cells lack protection and makes it difficult to face the complex in vivo environment. The gelatin methacryloyl (GelMA) hydr...
Mesenchymal stem cell extracellular vesicle vascularization bioactivity and production yield are responsive to cell culture substrate stiffness [0.03%]
细胞培养基质刚度影响间充质干细胞源性胞外囊泡促血管生成活性和释放量
Emily H Powsner,Stephanie M Kronstadt,Kristin Nikolov et al.
Emily H Powsner et al.
Mesenchymal stem cell-derived extracellular vesicles (MSC EVs) are an attractive therapeutic option for regenerative medicine applications due to their inherently pro-angiogenic and anti-inflammatory properties. However, reproducible and co...