Use of a human immortalized microglia cell line to study recognition, phagocytosis, and intracellular survival of Cryptococcus neoformans [0.03%]
利用人类微胶质细胞系研究新型隐球菌的识别、吞噬及胞内生存能力
Robbi L Ross,Kassandra Arias-Parbul,Zane M Douglass et al.
Robbi L Ross et al.
Cryptococcus neoformans, the etiological agent of cryptococcal meningitis (CM) is a globally distributed environmental yeast that mainly causes infections in immunocompromised individuals. Particularly in low-resource countries, the mortali...
Gut microbiota and parasite dynamics in an Amazonian community undergoing urbanization in Colombia [0.03%]
哥伦比亚一个经历城市化的亚马逊社区中的肠道微生物群和寄生虫动态变化
Sebastián Díaz,Amie J Eisfeld,Mónica Palma-Cuero et al.
Sebastián Díaz et al.
Studies on human gut microbiota have recently highlighted a significant decline in bacterial diversity associated with urbanization, driven by shifts toward processed diets, increased antibiotic usage, and improved sanitation practices. Thi...
Nuclear, mitochondrial, and Wolbachia endosymbiont genomes of Onchocerca lupi, Portugal [0.03%]
葡萄牙的耳痒螨（Onchocerca lupi）的核基因组，线粒体基因组和沃氏菌内共生体基因组
Maria Stefania Latrofa,Ilenia Urso,Elisabetta Notario et al.
Maria Stefania Latrofa et al.
Zoonotic Onchocerca lupi (Spirurida, Onchocercidae) has attracted the interest of the scientific community worldwide, by causing severe ocular infections in domestic animals (dogs, cats) and can infect wild carnivores (wolves, coyotes), as ...
Multispecies transcriptomics reveals influenza A virus modulation of Streptococcus pneumoniae EF3030 infection in human lung epithelium and murine lung [0.03%]
多物种转录组学揭示了流感病毒调节人肺上皮细胞和小鼠肺中的肺炎链球菌感染
Adonis D&#x;Mello,Erin Y Earnhardt,Jessica R Lane et al.
Adonis D&#x;Mello et al.
Streptococcus pneumoniae (Spn) is typically an asymptomatic colonizer of the nasopharynx, but it also causes pneumonia and disseminated disease affecting various host anatomical sites. To delineate host-pathogen transcriptional interactions...
Bifidobacterium infantis- a key (late) colonizer of the infant gut? [0.03%]
婴儿双歧杆菌-婴儿肠道中的一种关键（晚期）定植菌？
Martin F Laursen
Martin F Laursen
Human milk oligosaccharide (HMO)-degrading Bifidobacterium species are key early colonizers of the gut and influence gut and immune maturation. Loss of these taxa, particularly Bifidobacterium infantis, in many industrialized populations ha...
The vaginal microbiome of pregnant people living with HIV on antiretroviral therapy in the Democratic Republic of Congo: a pilot study and global meta-analysis [0.03%]
接受抗逆转录病毒治疗的刚果民主共和国HIV感染者阴道微生物组的研究：一项试点研究和全球荟萃分析
Kimberley S Ndlovu,Ricardo R Pavan,Jacqueline Corry et al.
Kimberley S Ndlovu et al.
Recent studies reveal that a suboptimal vaginal microbiome (VMB), including the enrichment of anaerobic bacteria associated with multiple female genital disorders, is linked to adverse pregnancy and birth outcomes in pregnant people. Proble...
p24 family proteins are critical for cell wall integrity, protein secretion, and virulence in Candida albicans [0.03%]
白色念珠菌P24家族蛋白对于细胞壁的完整性、蛋白质分泌及毒力是必不可少的
Xiangtai Yu,Hao Cui,Yifei Liu et al.
Xiangtai Yu et al.
Candida albicans is a fungal commensal and also a prevalent pathogen of humans. p24 proteins are a family of type I membrane proteins regarded as cargo receptors for endoplasmic reticulum (ER) to Golgi transport and are thought to be involv...
Zinc-enhanced activity of an antimicrobial halogenated phenazine against Streptococcus mutans and other gram-positive bacteria [0.03%]
锌增强型抗菌卤化菲挫类化合物对齿链球菌和其他革兰氏阳性菌的作用
Jessica K Kajfasz,Hannah B Hosay,Qiwen Gao et al.
Jessica K Kajfasz et al.
Halogenated phenazine (HP) compounds have shown promise as antimicrobial agents, particularly against biofilm-associated Gram-positive pathogens. Among these compounds, HP-29 demonstrates potent activity against methicillin-resistant Staphy...
Increased triacylglyceride and ceramide levels are key for MERS-CoV replication [0.03%]
梅尔堡病毒复制依赖三酰基甘油和丝氨醇水平升高
Hugh D Mitchell,Jennifer Kyle,Kristin Engbrecht et al.
Hugh D Mitchell et al.
Emerging viruses remain a threat to human health; however, many aspects of their infection cycle are still poorly understood. Host lipid structures and abundances are observed to be significantly altered during infection, and the mechanisms...
Acinetobacter enrichment shapes composition and function of the bacterial microbiota of field-grown tomato plants [0.03%]
不动杆菌富集影响田间生长的番茄植株细菌微生物群的组成和功能
Senga Robertson,Alexandros Mosca,Saira Ashraf et al.
Senga Robertson et al.
Tomato is a staple crop and an excellent model to study host-microbiota interactions in the plant food chain. In this study, we describe a "lab-in-the-field" approach to investigate the microbiota of field-grown tomato plants. High-throughp...