The etiology of exudative cutaneous ulcers in a yaws-endemic community prior to receipt of antimicrobials is similar to that found in communities after mass treatment with azithromycin [0.03%]
在一个接受抗生素治疗之前雅司病流行社区，渗出性皮肤溃疡的病因与使用了阿奇霉素后的社区类似
Julie A Brothwell,Evelyn Toh,Yue Xing et al.
Julie A Brothwell et al.
Mass drug administration (MDA) of azithromycin (AZ) and case finding and treatment of children with cutaneous ulcers (CUs) have been trialed as strategies to eliminate yaws. Metagenomic sequencing of CU swabs obtained from children 3 to 4 y...
Geographical diet variations and microbial diversity: insights into François' langur's adaptive strategies [0.03%]
地理饮食变化和微生物多样性： Francois叶猴适应策略的启示
Heqin Cao,Xiongwei Yang,Linzheng Hu et al.
Heqin Cao et al.
The diversity in foraging behavior observed among species is indicative of their ability to adapt to specific environmental conditions, with dietary differences playing a crucial role in shaping the composition of gut microbiota. However, t...
High-resolution imaging techniques to interrogate virus-host interactions [0.03%]
高分辨率成像技术阐释病毒与宿主相互作用
Isabel Amaya,Chelsey C Spriggs
Isabel Amaya
Viruses are obligate parasites that rely extensively on host cellular machinery to complete their life cycles. Therefore, examining the fundamental nature behind how viruses interact with their hosts can teach us more about the pathogenesis...
Katherine Rhodes
Katherine Rhodes
Katherine Rhodes is a bacteriologist working in the field of host-microbe interaction. In this mSphere of Influence article, she reflects on how two papers, "Spatial ecology of the human tongue dorsum microbiome" by S. Wilbert, J. Mark Welc...
A requirement for Acinetobacter baumannii purine biosynthesis during lung infection is exacerbated by host zinc deficiency [0.03%]
宿主锌缺乏会加剧肺部感染期间阿氏不动杆菌嘌呤生物合成的需要
Lauren D Palmer,Hannah R Noel,Kacie A Traina et al.
Lauren D Palmer et al.
Acinetobacter baumannii is a leading cause of hospital-acquired infections, including ventilator-associated pneumonia. Dietary zinc deficiency is a major risk factor for pneumonia, and hospitalized patients at risk for A. baumannii infectio...
Development of nanobody-conjugated LL37 for synergistic therapy against MDR Acinetobacter baumannii [0.03%]
开发纳米抗体结合的LL37用于协同治疗多重耐药鲍曼不动杆菌
Apisitt Thaiprayoon,Worrapoj Oonanant,Siriphan Boonsilp et al.
Apisitt Thaiprayoon et al.
Multidrug resistance (MDR) of the pathogen Acinetobacter baumannii is a major challenge to global healthcare due to the limited treatment options. The emergence of MDR bacteria necessitates innovative therapeutic approaches, especially give...
Santiago Castillo-Ramírez,Rafael López-Sánchez,Humberto Peralta
Santiago Castillo-Ramírez
The genus Acinetobacter is vast and diverse regarding its hosts. However, it is best known as an opportunistic pathogen that causes hard-to-treat nosocomial infections. Yet, some species of the genus can be beneficial for some hosts. Such i...
New hypothesis: a gut-lipid-kidney axis in constipated CKD patients-insights from multi-omics triangulation [0.03%]
新假说：便秘CKD患者的肠道-脂质-肾脏轴-多组学三角分析的新见解
Yichen Liu,Jin Zhao,Jinguo Yuan et al.
Yichen Liu et al.
Patients with chronic kidney disease (CKD) frequently experience constipation, often linked to gut microbiota disruptions. We hypothesized that constipation is not merely a comorbidity but a driver of adverse outcomes through a specific hos...
Achromobacter xylosoxidans isolates exhibit genome diversity, variable virulence, high levels of antibiotic resistance, and potential intrahost evolution [0.03%]
无色杆菌的基因组多样性、毒力、高水平抗生素抗性及其潜在的体内适应性演化
Pooja Acharya,Cameron Lloyd,Ngoc Thien Lam et al.
Pooja Acharya et al.
Achromobacter xylosoxidans is an emerging pathogen characterized by high levels of antibiotic resistance (AR) and increasing infection rates worldwide. This motile, opportunistic pathogen is widely distributed in the environment and can cau...
Co-occurrence network analysis reveals novel associations between the neonatal airway microbiome and bronchopulmonary dysplasia risk: an observational, population-based study [0.03%]
共现网络分析揭示了新生儿呼吸道微生物组与支气管肺发育不良风险之间的新型关联：一项基于人群的观察性研究
Liang Gao,Yingying Qiu,Xinzhu Lin et al.
Liang Gao et al.
To evaluate the association between respiratory tract microorganisms at birth and the subsequent development and severity of bronchopulmonary dysplasia (BPD) in preterm infants. This prospective cohort study enrolled 98 preterm infants (ges...