Novel Primer Design for Significantly Reducing Fluorescent Interferences in the Synthesis of DNA-Templated Copper Nanoclusters for the Detection of the HLA-B*5801 Gene [0.03%]
设计新型引物以显著降低铜纳米团簇合成中的荧光干扰，用于HLA-B*5801基因的检测
Ke-Peng Lai,Bo-Yu Liu,Wei-Lung Tseng et al.
Ke-Peng Lai et al.
The optimal sequence for synthesizing copper nanoclusters is a promising research area. Initially, random dsDNA sequences yielded low fluorescence intensity, which constrained visual detection under UV light. Poly-AT dsDNA sequences later p...
Tyrosinase-Activated MRI and PET Probes for Selective Melanoma Imaging [0.03%]
用于黑色素瘤选择性成像的酪氨酸酶激活MRI和PET探针
Zuhua Zeng,Ying Tan,Tiantian Luo et al.
Zuhua Zeng et al.
Melanoma is one of the most aggressive forms of skin cancer. Accurate and early diagnosis of melanoma is crucial for improving patient outcomes. This study develops two TYR-activatable molecular probes, Mn-TyrEDTA and Al-18F-TyrEDTA, for th...
Noninvasive Diagnosis of Early-Stage Chronic Kidney Disease and Monitoring of the Hemodialysis Process in Clinical Practice via Exhaled Breath Analysis Using an Ultrasensitive Flexible NH3 Sensor Assisted by Pattern Recognition [0.03%]
利用超灵敏柔性氨气传感器结合模式识别分析呼出气体实现慢性肾病早期无创诊断及透析过程监测
Xin Zhao,Xiaoyu You,Zhenzhen Wang et al.
Xin Zhao et al.
To achieve the early diagnosis of chronic kidney disease (CKD), noninvasive hemodialysis monitoring, and accurate determination of dialysis duration and adequacy, a noninvasive, point-of-care, user-friendly device should be developed. Here,...
High-Performance Co3O4 Nanoparticle-Based Gas Sensor for Leakage Detection of Eco-Friendly Insulating Gas C4F7N [0.03%]
用于检测环保绝缘气体C4F7N泄漏的高性能Co3O4纳米粒子气体传感器
Song Xiao,Yuhang Xue,Zhanyuan Li et al.
Song Xiao et al.
Perfluoroisobutyronitrile (C4F7N), an eco-friendly insulating gas, has been extensively utilized in diverse gas-insulated equipment (GIE) to replace the most potent greenhouse gas SF6. Nonetheless, given the low toxicity of C4F7N, the poten...
Single-Particle Collision Electrochemical Biosensor Developed by a Typical Alkaline Phosphatase-Catalyzed Silver Deposition Reaction [0.03%]
单颗粒碰撞型电化学生物传感器通过碱性磷酸酶催化的银沉积反应研制
Fangfang Yang,Jieyu Zhang,Li Wang et al.
Fangfang Yang et al.
Considering the intrinsic importance of alkaline phosphatase (ALP) as a biomarker in disease monitoring and as a mostly widely used biolabel for signal transmission in bioanalysis, the development of a new ALP assay method is highly pursued...
Surface-Enhanced Raman Spectroscopy and Multivariate Analysis for Elucidating Mechanisms of Action in Antibacterial Agents [0.03%]
用于阐明抗菌剂作用机制的表面增强拉曼光谱和多元分析
Der Vang,Jonathan Pahren,Emily Duderstadt et al.
Der Vang et al.
Antibiotic and antibacterial-resistant bacteria continue to pose a global-health threat. Understanding the mechanism of action (MoA) of antibacterial agents is crucial for developing precise and novel treatment methods. Traditionally, the M...
Identification of Gas Mixture Components with Multichannel Hierarchical Analysis of Time-Resolved Hyperspectral Data [0.03%]
基于时间分辨高光谱数据多通道层次化分析的气体混合物组分识别
Eunji Choi,Tae-In Jeong,Thanh Mien Nguyen et al.
Eunji Choi et al.
Chemical vapor sensors are essential for various fields, including medical diagnostics and environmental monitoring. Notably, the identification of components in unknown gas mixtures has great potential for noninvasive diagnosis of diseases...
Construction of Bifunctional Protein/Peptide Complex for Sensitive Detection of Transglutaminase 2 [0.03%]
双功能蛋白/肽复合物的构建用于敏感检测谷氨酰胺转氨酶2
Yiwei Han,Yanbing Wu,Jianyang Lu et al.
Yiwei Han et al.
Bifunctional protein complexes play essential roles in the biomedical field, particularly in biochemical analysis. However, traditional protein engineering methods (e.g., gene fusion and covalent modification) suffer limitations of complex ...
n/ p-Type Doping Modulation of the Adsorption and Selection Behavior of Harmful Gas Molecules on the Surface of SWCNTs for Enhanced Gas-Sensing Performance [0.03%]
SWCNTs表面有害气体分子的吸附和选择行为的n/p型掺杂调制以增强气敏性能
Xinxia Li,Xinyuan Tang,Zihan Wang et al.
Xinxia Li et al.
Single-walled carbon nanotubes (SWCNTs) are a promising candidate material for detecting harmful gases due to their unique advanced character, but their gas-sensing properties still need to be improved. With the aim of exploring more effect...
NiO/ZnO Nanocomposites for Multimodal Intelligent MEMS Gas Sensors [0.03%]
用于多模式智能MEMS气体传感器的NiO / ZnO纳米复合材料
Jiaqing Zhu,Lechen Chen,Wangze Ni et al.
Jiaqing Zhu et al.
Gas sensor arrays designed for pattern recognition face persistent challenges in achieving high sensitivity and selectivity for multiple volatile organic compounds (VOCs), particularly under varying environmental conditions. To address thes...