Engineered Antifouling Peptides with Sarcosine Branches for Robust Electrochemical Detection of the HER2 Biomarker in Real Biological Samples [0.03%]
一种用于真实生物样品中HER2生物标志物的稳健型电化学生物传感检测系统及其应用：工程抗污染肽及其制备方法
Hao Zhou,Mingjun Shi,Wenhao Yang et al.
Hao Zhou et al.
In complex biological matrices, the nonspecific adsorption phenomena occurring on the surfaces of electrochemical biosensors represent a considerable challenge for the precise detection of targets in heterogeneous biological samples. Furthe...
Endoplasmic Reticulum Stress Induces Liquid-Liquid Phase Separation of GRP78 and Modulates Protein Aggregation Dynamics [0.03%]
内质网应激诱导GRP78液-液相分离并调控蛋白质聚集动力学
Jiaqi Li,Xiangyu Zi,Jiabao Fang et al.
Jiaqi Li et al.
Abnormal protein aggregation is a hallmark of neurodegenerative diseases, disrupting cellular homeostasis. Glucose-regulated protein 78 (GRP78), a key endoplasmic reticulum (ER) chaperone, plays a crucial role in protein folding and the ER ...
Yingying Zhang
Yingying Zhang
Amplification-Free CRISPR/Cas12a-Based Electrochemical Biosensor with Enhanced Sensitivity for Viral Detection [0.03%]
一种用于病毒检测的灵敏增强型无信号放大CRISPR/Cas12a电化学生物传感器
Yejin Lee,Jin-Ho Lee,Taek Lee et al.
Yejin Lee et al.
To detect contagious viral nucleic acids, traditional biosensors often require target amplification steps or use fluorescence and Raman probes tagged on nucleic acids, which are time-consuming, complex, and expensive. Recently, the CRISPR/C...
Standardization of Microsampling Technologies for Accurate Sensing and Reliable Diagnostics [0.03%]
准确传感和可靠诊断的微采样技术标准化
Andrea C Mora,Charles R Mace
Andrea C Mora
The COVID-19 pandemic demonstrated the debilitating effect of overreliance on centralized sampling and testing, and generated significant momentum to investigate and validate sample types that are alternatives to the gold standard (e.g., an...
Direct Current Redox Imaging of Single Retinal Pigment Epithelial Cells Using Light-Addressable Electrochemistry at Semiconductor Electrodes [0.03%]
基于半导体电极的光寻址电化学单个视网膜色素上皮细胞直接直流氧化还原成像
Mingrui Jiang,Sen Wang,Kangying Liu et al.
Mingrui Jiang et al.
Light-addressable electrochemistry (LAE) enables the activation and detection of localized faradaic electrochemical processes on a flat, unconstructed semiconductor electrode through targeted light illumination, making it a promising approa...
Heterostructure of Chemical Vapor Deposition (CVD) Graphene and H2 Plasma-Treated SnO2 Nanoparticle Films for Room Temperature Sensing of SO2 [0.03%]
化学气相沉积（CVD）石墨烯与氢等离子体处理SnO2纳米颗粒薄膜异质结构室温传感器用于检测SO2气体
Yang Liu,Tianxing Chen,Yuming Chen
Yang Liu
In this article, we aim to develop SO2 sensors that operate at room temperature (25 °C) by using graphene synthesized through chemical vapor deposition and spin-coated SnO2 films. H2 plasma treatment was applied to the SnO2 films, and phot...
Increasing the Surface Activity of 2D Ultrathin Co3O4 by Indium Doping for TEA Sensing [0.03%]
掺铟提高二维超薄Co3O4的表面活性以用于TEA气体传感检测
Tianrun Zheng,Yi Lu,Yilin Wang et al.
Tianrun Zheng et al.
Optimizing and improving the surface activity of Co3O4 sensing materials are crucial for applications in triethylamine detection. Herein, indium-doped Co3O4 hollow microflowers (InCo HMfs), assembled from ultrathin nanosheets, were prepared...
Predictive Analysis of Dental Caries Risk via Rapid Urease Activity Evaluation in Saliva Using a ZIF-8 Nanoporous Membrane [0.03%]
基于 saliva 中快速尿素酶活性评价的牙齿蛀牙风险预测分析采用 ZIF-8 纳米多孔膜
Bao-Yi Zhou,Xiao-Yan Shi,Zhao-Ying Luo et al.
Bao-Yi Zhou et al.
Despite a decrease in the incidence of dental caries over the past four decades, it remains a widespread public health concern. The multifactorial etiology of dental caries complicates effective prevention and early intervention efforts, un...
Ultrasensitive and Selective Detection of Dopamine Through Substituent-Regulated Evolution of Quantum Defects [0.03%]
通过取代基调节量子缺陷演变实现多巴胺的 ultra灵敏和选择性检测
Taishan Yin,Yuqing Zhao,Jiaqi Zhang et al.
Taishan Yin et al.
Accurate detection and analysis of biomolecules like dopamine (DA) are vital for monitoring human health, particularly given DA's critical roles in a lot of medical disorders such as depression, Parkinson's and Alzheimer's diseases, and myo...