Making Prodrugs Stick Around: Engineering Protease-Activated Tumor Retention [0.03%]
让前药驻留：工程学酶激活的肿瘤滞留机制
Robin Kryštůfek,Jan Konvalinka
Robin Kryštůfek
Kang et al. combine protease-triggered activation with membrane trapping, keeping drugs in tumors longer and boosting delivery, imaging, and therapy. Pub...
Expanding the Trifluoroborate Toolbox: Pyridinium Scaffolds for PET Tracer Development [0.03%]
扩展三氟化硼工具箱：用于PET示踪剂开发的吡啶inium支架
Antonio A W L Wong,David M Perrin
Antonio A W L Wong
One-step synthesis and tunable physicochemical properties position pyridinium-trifluoroborates as a versatile complement to existing radioprosthetics. Pu...
Daniel S Parsons,Yueting Sun
Daniel S Parsons
An applied electric field gives rise to a significant reduction in the reaction time for the synthesis of select metal. Published 2026 by American Chemic...
Building Chemistry from "Lego" Blocks: Metal-Organic Frameworks after the 2025 Nobel Prize [0.03%]
乐高积木搭建化学：2025年诺贝尔奖之后的金属有机框架材料研究进展
Grace C Thaggard,Danielle N Smith,Sumanta Basak et al.
Grace C Thaggard et al.
Leading up to the 2025 Nobel Prize in Chemistry, the field of metal-organic frameworks (MOFs) shifted the material design paradigm by allowing for discrete molecular building blocks to be extended into predesigned porous functional material...
MOF-Based Lithium Oxygen Batteries: Status and Prospects from Material Design to System Integration [0.03%]
基于金属有机骨架的锂氧电池：从材料设计到系统集成的现状和前景
Shuaiyu Gao,Yuqing Dong,Malin Li et al.
Shuaiyu Gao et al.
Lithium oxygen batteries (LOBs) offer exceptional theoretical energy density but face formidable challenges due to the sluggish kinetics of the oxygen reduction and evolution reactions (ORR/OER). This review delineates the pivotal role of m...
Modulating Viscoelasticity and Live Cell Response with Fibrillar Peptide Polymers [0.03%]
具有纤维肽聚合物的粘弹性及活细胞响应调节研究
Clara Middleton,Laurel Kroo,Todd Emrick
Clara Middleton
Motivated by the sensitivity of cancer to the mechanics of surrounding tissue, synthetic fibrillar peptide hydrogels successfully controlled growth. Publ...
Replacing Quantum Chemistry With Machine-Learned Interatomic Potentials: Revolution or Evolution? [0.03%]
用机器学习的相互作用势取代量子化学：革命还是进化？
Andrew J Medford,David S Sholl
Andrew J Medford
A long-standing goal in computational chemistry and materials science has been the development of general-purpose interatomic force fields that define the energy and forces associated with arbitrary sets of atoms. This task can be accomplis...
Freezing the Electronic Wave: Uncovering the Atomistic Structure of Charge Density Waves in 1D Metallic MOFs [0.03%]
冻结电子波：一维金属MOF中电荷密度波的原子结构解析
Matthew J Cliffe
Matthew J Cliffe
Advanced crystallographic determination of the structures of porous metallic metal-organic frameworks uncovers strong evidence of quantum electronic behavior. ...
Molecular Diradical Spin Qubits in a Crystalline Host as a Platform for Quantum Sensing [0.03%]
分子态双自由基自旋量子比特在晶体宿主中的平台用于量子传感研究
Sebastian M Kopp,Jonathan R Palmer,Brian T Phelan et al.
Sebastian M Kopp et al.
Doping a luminescent tris-(2,4,6-trichlorophenyl)-methyl diradical m (TTM) 2 into a host crystal of its diamagnetic precursor m (HTTM) 2 creates a molecular color center with enhanced optical-spin interface properties important for quantum ...
Hydride and Seek: Comparing Crystallographic Hydride Placement Techniques with an Open-Shell Cobalt Complex [0.03%]
化氢于无形：用开壳层钴配合物比较晶体学置氫技术
Ryan S Donnelly,Theodore J Gerard,Sebastian M Krajewski et al.
Ryan S Donnelly et al.
Locating hydrides is crucial in organometallic chemistry but difficult to do accurately using X-ray diffraction. Electron diffraction has been proposed as a way to overcome this problem but has not been systematically compared to neutron di...