Effects of specialised physiotherapy on mortality in Parkinson's disease: a prospective observational study [0.03%]
物理治疗对帕金森病患者死亡率影响的前瞻性观察研究
Jan H L Ypinga,Lieke H H M Boonen,Marten Munneke et al.
Jan H L Ypinga et al.
Previous studies found that specialised allied health interventions in people with Parkinson's disease (PD) are associated with fewer complications and lower costs, as compared to usual care. Here we studied the association between speciali...
Classification of Parkinson's disease and isolated REM sleep behaviour disorder: delineating progression markers from the sebum volatilome [0.03%]
帕金森病和孤立性快速眼动睡眠行为障碍的分类：从皮脂挥发组分中界定进展标志物
Caitlin Walton-Doyle,Beatrice Heim,Eleanor Sinclair et al.
Caitlin Walton-Doyle et al.
Parkinson's Disease (PD) has been associated with a distinct odour, emanating from the skin and strongest in sebum-rich areas. Here, volatile components from sebum were analysed directly with Thermal Desorption Gas Chromatography - Mass Spe...
Circadian clock dysfunction in Parkinson's disease: mechanisms, consequences, and therapeutic strategy [0.03%]
帕金森病的昼夜钟功能障碍：机制、后果及治疗策略
Müge Yalçin,Valentina Grande,Tiago Fleming Outeiro et al.
Müge Yalçin et al.
Parkinson's Disease (PD) is a prevalent neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. This leads to hallmark motor features that include bradykinesia, resting tremor, rigid...
REM density in Parkinson's disease: association with motor, cognitive, autonomic function, and dopaminergic medication [0.03%]
帕金森病的REM睡眠密度与运动、认知、自主功能和多巴胺能药物的关系
Andrew Dagay,Shlomit Katzav,Noa Elisha et al.
Andrew Dagay et al.
Recent work has shown that REM density, defined as the number of rapid eye movements per REM sleep minute, is decreased in people with Parkinson's disease (PD) and is associated with greater bradykinesia, suggesting a motor component. This ...
Fasting and postprandial Ghrelin levels in Parkinson's disease: a systematic review and meta-analysis [0.03%]
帕金森病的空腹和餐后 ghrelin 水平：系统回顾及荟萃分析
Henrique José Cavalcanti Bezerra Gouveia,Osmar Henrique Dos Santos-Júnior,Johannes Frasnelli
Henrique José Cavalcanti Bezerra Gouveia
Parkinson's disease (PD) is a progressive movement disorder with motor and non-motor symptoms, including gastrointestinal and olfactory dysfunctions. These symptoms may be associated with plasma concentrations of the hormone ghrelin. Lower ...
Regional-specific structural and functional changes of posterior cerebellar vermis across different stages of Parkinson's disease with gait dysfunction [0.03%]
帕金森病伴步态障碍患者后小脑蚓部结构和功能的阶段性改变及其区域性差异研究
Liuzhenxiong Yu,Jinying Han,Xin Chen et al.
Liuzhenxiong Yu et al.
Stage-specific roles of posterior cerebellar vermis (PV) subdivisions, the posterior superior vermis (PSV) and posterior inferior vermis (PIV), in Parkinson's disease postural instability/gait difficulty (PD-PIGD) remain unclear. This retro...
Author Correction: Cortical microstructural abnormalities in dementia with Lewy bodies and their associations with Alzheimer's disease copathologies [0.03%]
作者更正：路易体痴呆皮层微结构异常及其与阿尔茨海默病共病理的关系
Elijah Mak,Robert I Reid,Scott A Przybelski et al.
Elijah Mak et al.
Published Erratum
NPJ Parkinson's disease. 2025 Jul 12;11(1):209. DOI:10.1038/s41531-025-01068-y 2025
Transformer-based long-term predictor of subthalamic beta activity in Parkinson's disease [0.03%]
基于Transformer的帕金森病丘脑底核电活动长期预测模型
Salvatore Falciglia,Laura Caffi,Claudio Baiata et al.
Salvatore Falciglia et al.
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a mainstay treatment for patients with Parkinson's disease (PD). The adaptive DBS approach (aDBS) modulates stimulation, based on the power in the beta range ([12-30] Hz) of S...
Parkinson's paradox: alpha-synuclein's selective strike on SNc dopamine neurons over VTA [0.03%]
帕金森悖论：α-突触核蛋白对黑质多巴胺神经元的选择性攻击胜过中脑腹侧被盖区神经元
L Phan,D Miller,A Gopinath et al.
L Phan et al.
A central question in Parkinson's disease (PD) and related synucleinopathies research is why dopamine neurons in the substantia nigra pars compacta (SNc) are more vulnerable than those in the ventral tegmental area (VTA). We investigated ho...
A generalizable and open-source algorithm for real-life monitoring of tremor in Parkinson's disease [0.03%]
一种通用且开源的算法，用于帕金森病患者震颤的日常生活监测
Nienke A Timmermans,Roberta Terranova,Diogo C Soriano et al.
Nienke A Timmermans et al.
Wearable sensors can objectively and continuously monitor daily-life tremor in Parkinson's Disease (PD). We developed an open-source algorithm for real-life monitoring of PD tremor which achieves generalizable performance across different w...