Saving the Devils Is in the Details: Tasmanian Devil Facial Tumor Disease Can Be Eliminated with Interventions [0.03%]
细节决定魔鬼的命运——面部肿瘤病可以被根除以拯救 tasmanian 魔鬼种群
Brian Drawert,Andrew S Flies,Sean Matthew et al.
Brian Drawert et al.
Tasmanian Devils facial tumor disease (DFTD) is severely impacting the population of this wild animal. We developed a computational model of the population of Tasmanian Devils, and the change induced by DFTD. We use this model to test possi...
GillesPy2: A Biochemical Modeling Framework for Simulation Driven Biological Discovery [0.03%]
GillesPy2：一种基于模拟的生物发现化学生物学建模框架
Sean Matthew,Fin Carter,Joshua Cooper et al.
Sean Matthew et al.
Stochastic modeling has become an essential tool for studying biochemical reaction networks. There is a growing need for user-friendly and feature-complete software for model design and simulation. To address this need, we present GillesPy2...
Optimization of Agent-Based Models Through Coarse-Graining: A Case Study in Microbial Ecology [0.03%]
通过粗粒化优化基于智能体的模型：微生物生态学中的一个案例研究
Sherli Koshy-Chenthittayil,Pedro Mendes,Reinhard Laubenbacher
Sherli Koshy-Chenthittayil
Optimization and control are important objectives across biology and biomedicine, and mathematical models are a key enabling technology. This paper reports a computational study of model-based multi-objective optimization in the setting of ...
Boris Aguilar,Pan Fang,Reinhard Laubenbacher et al.
Boris Aguilar et al.
One of the ultimate goals in systems biology is to develop control strategies to find efficient medical treatments. One step towards this goal is to develop methods for changing the state of a cell into a desirable state. We propose an effi...
Alexis White,Elsa Schaefer,Chelsea Wright Thompson et al.
Alexis White et al.
A mathematical model for a two-pathogen, one-tick, one-host system is presented and explored. The model system is based on the dynamics of Amblyomma americanum, Rickettsia parkeri, and Rickettsia amblyommatis. The goal of this model is to d...
Modeling the Diet Dynamics of Children: the Roles of Socialization and the School Environment [0.03%]
儿童膳食行为的动力学模型及其在学校环境中的社会化作用
Muntaser Safan,Anarina L Murillo,Devina Wadhera et al.
Muntaser Safan et al.
Childhood obesity is a health emergency in many parts of the world including the U.S. and, consequently, identifying local, regional or national intervention models capable, of altering the dynamics of obesity at scales that make a differen...
Technology as a tool in teaching quantitative biology at the secondary and undergraduate levels: a review [0.03%]
科技在中学和大学水平定量生物学教学中的作用：综述
Miranda M Chen,S M Scott,Jessica D Stevens
Miranda M Chen
Since the publication of the National Research Councils Report BIO2010, e orts have increased to better integrate mathematics and biology in undergraduate education. Unfortunately, equivalent e orts to introduce these quantitative topics at...
H Cho,K Ayers,L DePills et al.
H Cho et al.
Here we present a mathematical model of movement in an abstract space representing states of cellular differentiation. We motivate this work with recent examples that demonstrate a continuum of cellular differentiation using single cell RNA...
The Evolution of Cooperation is Affected by the Persistence of Fitness Effects, the Neighborhood Size and their Interaction [0.03%]
合作的进化受适应度效应持久性、邻居规模及其互作的影响
Eli Thompson,Jasmine Everett,Jonathan T Rowell et al.
Eli Thompson et al.
Evolutionary Game Theory and the Prisoner's Dilemma (PD) Game in particular have been used to study the evolution of cooperation. We consider a population of asexually reproducing, age-structured individuals in a two-dimensional square latt...