Intrinsic Excitability in Layer IV-VI Anterior Insula to Basolateral Amygdala Projection Neurons Correlates with the Confidence of Taste Valence Encoding [0.03%]
第四-第六层前部脑岛至基底外侧杏仁核投射神经元的内在兴奋性与味觉效价编码的信心相关
Sailendrakumar Kolatt Chandran,Adonis Yiannakas,Haneen Kayyal et al.
Sailendrakumar Kolatt Chandran et al.
Avoiding potentially harmful, and consuming safe food is crucial for the survival of living organisms. However, the perceived valence of sensory information can change following conflicting experiences. Pleasurability and aversiveness are t...
Chemogenetic Enhancement of cAMP Signaling Renders Hippocampal Synaptic Plasticity Resilient to the Impact of Acute Sleep Deprivation [0.03%]
增强cAMP信号可使海马突触的可塑性在急性睡眠剥夺的影响下保持稳定
Emily Nicole Walsh,Mahesh Shivarama Shetty,Kamran Diba et al.
Emily Nicole Walsh et al.
Sleep facilitates memory storage and even brief periods of sleep loss lead to impairments in memory, particularly memories that are hippocampus dependent. In previous studies, we have shown that the deficit in memory seen after sleep loss i...
How Characters Are Learned Leaves Its Mark on the Neural Substrates of Chinese Reading [0.03%]
学习汉字的方式会对中文阅读的神经基质产生影响
Jieyin Feng,Hoi Yan Mak,Jing Wang et al.
Jieyin Feng et al.
Understanding how the brain functions differently as one learns to read may shed light on the controversial nature of the reading ability of human being. Logographic writing system such as Chinese has been found to rely on specialized neura...
Basal Forebrain Chemogenetic Inhibition Converts the Attentional Control Mode of Goal-Trackers to That of Sign-Trackers [0.03%]
基底前脑的化学遗传抑制可将目标追踪者的注意控制模式转换为符号追踪者的控制模式
Aaron Kucinski,Cassandra Avila,Martin Sarter
Aaron Kucinski
Sign tracking versus goal tracking in rats indicate vulnerability and resistance, respectively, to Pavlovian cue-evoked addictive drug taking and relapse. Here, we tested hypotheses predicting that the opponent cognitive-behavioral styles i...
An Early Enriched Experience Drives an Activated Microglial Profile at Site of Corrective Neuroplasticity in Ten-m3 Knock-Out Mice [0.03%]
十号分子3基因敲除小鼠中早期丰富体验促进矫正性神经可塑性位点的小胶质细胞活化特性形成
Lara Rogerson-Wood,Justin Petersen,Abe Kairouz et al.
Lara Rogerson-Wood et al.
Environmental enrichment (EE) is beneficial for brain development and function, but our understanding of its capacity to drive circuit repair, the underlying mechanisms, and how this might vary with age remains limited. Ten-m3 knock-out (KO...
Localization of TRP Channels in Healthy Oral Mucosa from Human Donors [0.03%]
人供体健康口腔黏膜中瞬时受体电位通道的定位研究
Yalda Moayedi,Stephanie Michlig,Mark Park et al.
Yalda Moayedi et al.
The oral cavity is exposed to a remarkable range of noxious and innocuous conditions, including temperature fluctuations, mechanical forces, inflammation, and environmental and endogenous chemicals. How such changes in the oral environment ...
Increase in Tau Pathology in P290S Mapt Knock-In Mice Crossed with App NL-G-F Mice [0.03%]
携带App NL-G-F基因的P290S Mapt敲入小鼠中Tau病理的增加
Melissa Huang,Jennifer Macdonald,Isabelle Lavenir et al.
Melissa Huang et al.
Alzheimer's Disease (AD) is characterized by the pathologic assembly of amyloid β (Aβ) peptide, which deposits into extracellular plaques, and tau, which accumulates in intraneuronal inclusions. To investigate the link between Aβ and tau...
Neural Signatures of Actively Controlled Self-Motion and the Subjective Encoding of Distance [0.03%]
主动控制自运动的神经签名以及距离的主观编码
Constanze Schmitt,Milosz Krala,Frank Bremmer
Constanze Schmitt
Navigating through an environment requires knowledge about one's direction of self-motion (heading) and traveled distance. Behavioral studies showed that human participants can actively reproduce a previously observed travel distance purely...
Sensory Perturbations from Hindlimb Cutaneous Afferents Generate Coordinated Functional Responses in All Four Limbs during Locomotion in Intact Cats [0.03%]
来自后肢皮肤感受器的感觉扰动在完整猫的运动过程中产生所有四肢的功能反应
Angèle N Merlet,Pierre Jéhannin,Stephen Mari et al.
Angèle N Merlet et al.
Coordinating the four limbs is an important feature of terrestrial mammalian locomotion. When the foot dorsum contacts an obstacle, cutaneous mechanoreceptors send afferent signals to the spinal cord to elicit coordinated reflex responses i...
Roddy M Grieves,Michael E Shinder,Laura K Rosow et al.
Roddy M Grieves et al.
While the brain has evolved robust mechanisms to counter spatial disorientation, their neural underpinnings remain unknown. To explore these underpinnings, we monitored the activity of anterodorsal thalamic head direction (HD) cells in rats...