Characterization of optimal optogenetic stimulation paradigms to evoke calcium events in cortical astrocytes [0.03%]
表征最优光遗传刺激模式以在皮层星形胶质细胞中诱发钙事件
Lakshmini Balachandar,Carolina Moncion,Alejandro Suarez et al.
Lakshmini Balachandar et al.
Understanding the roles of astrocytic calcium signaling in multiple brain regulatory mechanisms including metabolism, blood flow, neuromodulation and neuroinflammation has remained one of the enduring challenges in glial biology. To delinea...
Depression levels are associated with reduced capacity to learn to actively avoid aversive events in young adults [0.03%]
抑郁症水平与年轻成年人主动回避不良事件的学习能力降低有关
Ryan J Tomm,Brandon J Forys,Liz Kalenteridis et al.
Ryan J Tomm et al.
Depression and anxiety are often characterized by altered reward-seeking and avoidance, respectively. Yet less is known about the relationship between depressive symptoms and specific avoidance behaviors. To address this gap, we conducted t...
Track-A-Worm 2.0: A Software Suite for Quantifying Properties of C. elegans Locomotion, Bending, Sleep, and Action Potentials [0.03%]
追踪蠕虫2.0：量化秀丽隐杆线虫运动、弯曲、睡眠和动作电位属性的软件套件
Kiranmayi Vedantham,Longgang Niu,Ryan Ma et al.
Kiranmayi Vedantham et al.
Comparative analyses of locomotor behavior and cellular electrical properties between wild-type and mutant Caenorhabditis elegans are crucial for exploring the gene basis of behaviors and the underlying cellular mechanisms. Although many to...
Test-Retest Reliability of TRF-Derived Measures of Cortical Tracking of the Speech Envelope [0.03%]
基于TRF的言语包络皮层追踪测量的重测信度
Heather R Dial,G Nike Gnanateja
Heather R Dial
Cortical tracking of the speech envelope is an emerging, noninvasive measure of neurophysiological processing of speech that is being widely adopted. It demonstrates good ecological validity, as it allows researchers to study human processi...
Hippocampal-prefrontal communication subspaces align with behavioral and network patterns in a spatial memory task [0.03%]
海马前额叶通讯子空间与空间记忆任务中的行为和网络模式一致
Ryan A Young,Justin D Shin,Ziyi Guo et al.
Ryan A Young et al.
Rhythmic network states have been theorized to facilitate communication between brain regions, but how these oscillations influence communication subspaces, i.e. the low-dimensional neural activity patterns that mediate inter-regional commu...
High Gamma Activity in the Infralimbic Cortex to Nucleus Accumbens Shell Pathway [0.03%]
内侧前额叶皮层至腹壳核环路的高频γ振荡活动
Elijah C Grablin,Joaquin E Douton,Regina M Carelli
Elijah C Grablin
Aversion modulation is a key component of hedonic processing, and its dysfunction is evident in psychiatric illnesses. The infralimbic cortex (IL) to nucleus accumbens shell (NAcSh) pathway is essential in hedonic processing in rodents but ...
The Beta Amyloid Core Hexapeptide Protects Against Full-Length Beta Amyloid-Induced Alteration of Dendritic Spine Morphology and Density [0.03%]
β淀粉样蛋白核心六肽保护全长β淀粉样蛋白引起的树突棘形态和密度的改变
Ruth M Shontell,David Araki,Kendra M Ormsbee et al.
Ruth M Shontell et al.
Pathological levels of beta amyloid (Aβ) lead to disruption and elimination of synapses in brain as the result of direct neurotoxicity as well as neuroinflammation. The synaptic impact of beta amyloid includes altered morphology and reduce...
The Oviposition Inhibitory Neuron is a potential hub of multi-circuit integration in the Drosophila brain [0.03%]
卵抑制神经元可能是果蝇大脑多回路整合的潜在中心
Rhessa A Weber Langstaff,Pranjal Srivastava,Alexander B Kunin et al.
Rhessa A Weber Langstaff et al.
Understanding how neural circuits integrate sensory and state information to support context-dependent behavior is a central challenge in neuroscience. Oviposition is a complex process during which a fruit fly integrates context and sensory...
Transplanting neural progenitor cells improves neural regulation but not hormonal reliance of cardiovascular function following spinal cord injury [0.03%]
脊髓损伤后移植神经前体细胞可改善心血管功能的神经调节但不能减少对激素的依赖性
Cameron T Trueblood,Fateme Khodadadi-Mericle,Zhifeng Qi et al.
Cameron T Trueblood et al.
High-level spinal cord injury (SCI) often reduces neural regulation of cardiovascular function. During the chronic phase, humoral regulation via the renin-angiotensin system (RAS) is enhanced to compensatorily maintaining blood pressure. It...