Ema Bokulić,Tila Medenica,Goran Sedmak
Ema Bokulić
The subthalamic nucleus (STN) is a small, excitatory nucleus that regulates the output of basal ganglia motor circuits. The functions of the STN and its role in the pathophysiology of Parkinson's disease are now well established. However, s...
Prefrontal Cortical to Mediodorsal Thalamus Projection Neurons Regulate Posterror Adaptive Control of Behavior [0.03%]
前额皮层投射到中介背侧丘脑的神经元调控行为错误后的适应性控制
Bastiaan Bruinsma,Tommy Pattij,Huibert D Mansvelder
Bastiaan Bruinsma
Adaptive control is the online adjustment of behavior to guide and optimize responses after errors or conflict. The neural circuits involved in monitoring and adapting behavioral performance following error are poorly understood. The prefro...
Development of an Open Face Home Cage Running Wheel for Testing Activity-Based Anorexia and Other Applications [0.03%]
开放式家用笼跑步轮的开发在基于活动的厌食症和其他应用中的测试
Nathan Godfrey,Kehan Chen,Temoor Tayyab et al.
Nathan Godfrey et al.
Running wheels for mice residing in the home cage are useful for the continuous measurement of locomotor activity for studies testing exercise interventions or exercise-induced effects on brain and metabolism. Here, we have developed an ope...
Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet Syndrome [0.03%]
针对Dravet综合征小鼠模型中癫痫及SUDEP的microRNA-134靶点研究
Rogério R Gerbatin,Joana Augusto,Gareth Morris et al.
Rogério R Gerbatin et al.
Dravet syndrome (DS) is a catastrophic form of pediatric epilepsy mainly caused by noninherited mutations in the SCN1A gene. DS patients suffer severe and life-threatening focal and generalized seizures which are often refractory to availab...
The Genomic Architecture of Pregnancy-Associated Plasticity in the Maternal Mouse Hippocampus [0.03%]
母鼠海马区妊娠相关可塑性的基因组架构
Alper Celik,Max Somer,Bharti Kukreja et al.
Alper Celik et al.
Pregnancy is associated with extraordinary plasticity in the maternal brain. Studies in humans and other mammals suggest extensive structural and functional remodeling of the female brain during and after pregnancy. However, we understand r...
Blood-Brain Barrier Disruption in Preclinical Mouse Models of Stroke Can Be an Experimental Artifact Caused by Craniectomy [0.03%]
颅骨切除导致的血脑屏障破坏很可能是中风动物模型中的实验伪影
Che-Wei Liu,Eric Yuhsiang Wang,Hwai-Lee Wang et al.
Che-Wei Liu et al.
The pathophysiological features of ischemia-related blood-brain barrier (BBB) disruption are widely studied using preclinical stroke models. However, in many of these models, craniectomy is required to confirm arterial occlusion via laser D...
Erratum: Dulac et al., "A Novel Neuron-Specific Regulator of the V-ATPase in Drosophila" [0.03%]
致读者的一封信：关于Dulac等人的论文“A Novel Neuron-Specific Regulator of the V-ATPase in Drosophila”的勘误书
Amina Dulac,Abdul-Raouf Issa,Jun Sun et al.
Amina Dulac et al.
Published Erratum
eNeuro. 2022 Oct 12;9(5):ENEURO.0389-22.2022. DOI:10.1523/ENEURO.0389-22.2022 2022
Spontaneous Cell Cluster Formation in Human iPSC-Derived Neuronal Spheroid Networks Influences Network Activity [0.03%]
人 iPSC 衍生的神经球网络中细胞簇的自发形成影响了网络活性
Carl-Johan Hörberg,Ulrica Englund Johansson,Fredrik Johansson et al.
Carl-Johan Hörberg et al.
Three-dimensional neuronal culture systems such as spheroids, organoids, and assembloids constitute a branch of neuronal tissue engineering that has improved our ability to model the human brain in the laboratory. However, the more elaborat...
Florian Eberhardt,Eric A Bushong,Sébastien Phan et al.
Florian Eberhardt et al.
Dendritic spines are submicron, subcellular compartments whose shape is defined by actin filaments and associated proteins. Accurately mapping the cytoskeleton is a challenge, given the small size of its components. It remains unclear wheth...
Oral Sensory Neurons of the Geniculate Ganglion That Express Tyrosine Hydroxylase Comprise a Subpopulation That Contacts Type II and Type III Taste Bud Cells [0.03%]
表达酪氨酸羟化酶的孤束核涎液神经元亚群与II型和III型味觉细胞形成突触联系
Tao Tang,Brian A Pierchala
Tao Tang
Oral sensory neurons of the geniculate ganglion (GG) innervate taste papillae and buds on the tongue and soft palate. Electrophysiological recordings of these neurons and fibers revealed complexity in the number of unique response profiles ...