Luminance matching in cognitive pupillometry is not enough: The curious case of orientation [0.03%]
认知瞳孔测量中的亮度匹配还不够：方位的奇特情况
Matthew A Parrella,Isshori Gurung,Michael A Grubb
Matthew A Parrella
Abrupt onsets reflexively shift covert spatial attention. Recent work demonstrated that trial-to-trial information about the probability of a peripheral onset modulated the magnitude of the attentional cueing effect (low-probability > high-...
Prefrontal and subcortical c-Fos mapping of reward responses across competitive and social contexts [0.03%]
竞争与社会情境下的奖赏反应的前额叶和皮层下脑区c-Fos图谱研究
Caroline De Paula Cunha Almeida,Meghan Cum,Elizabeth Illescas-Huerta et al.
Caroline De Paula Cunha Almeida et al.
Social animals compete for rewards to survive, yet the neural circuits underlying reward-based social competition remain unclear. The medial prefrontal cortex (mPFC) plays a key role in reward processing and social dominance, but whether it...
Electrophysiological Signatures of Planned and Unplanned Continuous Movement Termination in Parkinson's Disease [0.03%]
帕金森病中计划和非计划连续运动终止的电生理特征
Apoorva Karekal,Kelsey Schultz,Alexander P Rockhill et al.
Apoorva Karekal et al.
The ability to inhibit and adapt our behavior in response to changing stimuli is a critical component of everyday life. Individuals with Parkinson's disease (PD) may struggle to inhibit behavior, particularly in the presence of dopaminergic...
Odor experience stabilizes glomerular output representations in two mouse models of autism [0.03%]
两种自闭症小鼠模型中的气味体验稳定了glomerular输出表征
Kassandra L Sturm,Daryna Semak,Zoe A Scheier et al.
Kassandra L Sturm et al.
Novel stimuli can be stressful for individuals with Autism Spectrum Disorders (ASD), though repeated exposure can reduce this effect. In Cntnap2-/- and Shank3B+/- mouse models of ASD, novel background odors impaired behavioral target odor r...
Establishment of an Infrared-Camera-Based Home-Cage Tracking System Goblotrop [0.03%]
基于红外摄像的自动追踪系统Goblotrop的建立
Theo Gabloffsky,Katharina Schuster,Annelie Zimmermann et al.
Theo Gabloffsky et al.
Studying locomotor activity in animal models is crucial for understanding physiological, behavioral, and pathological processes. This study aimed to develop an artificial intelligence-based tracking system called Goblotrop, designed to loca...
A single NPFR neuropeptide F receptor neuron that regulates thirst behaviors in Drosophila [0.03%]
一种神经肽F受体神经元调节果蝇渴求行为
Donnoban Orozco Ramirez,Brian P Wang,Dan Landayan et al.
Donnoban Orozco Ramirez et al.
Thirst is a strongly motivated internal state that is represented in central brain circuits that are only partially understood. Water seeking is a discrete step of the thirst behavioral sequence that is amenable to uncovering the mechanisms...
Dissociation Between Simple and Complex Speech Motor Tasks Within Bilateral Motor Thalamus [0.03%]
双侧运动丘脑中简单和复杂语音运动任务的分离现象
Karim Johari,Joel I Berger,Andrea H Rohl et al.
Karim Johari et al.
Although clinical and experimental evidence highlight the role of thalamus in voluntary movement production, the involvement of thalamus in complex motor tasks such as speech production remains to be elucidated. The present study examined n...
Frazzled/DCC regulates gap junction formation at a Drosophila giant synapse [0.03%]
Frazzled/DCC调节果蝇巨大突触的缝隙连接形成
Juan Lopez,Jana Boerner,Kelli Robbins et al.
Juan Lopez et al.
Loss of function Frazzled/DCC mutants disrupt synaptogenesis in the Giant Fiber (GF) System of Drosophila We observe weaker physiology in loss-of-function (LOF) male and female specimens, characterized by longer latencies and reduced respon...
Brandon J Harvey,Viktor J Olah,Lauren M Aiani et al.
Brandon J Harvey et al.
Sleep-wake states bi-directionally interact with epilepsy and seizures, but the mechanisms are unknown. A barrier to comprehensive characterization and the study of mechanisms has been the difficulty of annotating large chronic recording da...
The PDGFBB-PDGFRβ pathway and Laminins in pericytes are involved in the temporal change of AQP4 polarity during Temporal Lobe Epilepsy Pathogenesis [0.03%]
血小板源性生长因子PDGFBB和PDGFRβ信号通路及周细胞层粘连蛋白在颞叶癫痫发生发展过程中调控AQP4极化方向的时相转换中的作用研究
Lin Lin,Hongxia Tang,Ke Cui et al.
Lin Lin et al.
This study aims to examine the changes in AQP4 polarity and pericyte vascularity during temporal lobe epilepsy (TLE) progression, with the goal of identifying potential drug targets or strategies to delay the onset and progression of TLE. C...