Agri-Food Extracts Effectiveness in Improving Antibacterial and Antiviral Properties of Face Masks: A Proof-of-Concept Study [0.03%]
从农业食品中提取有效成分以改善口罩的抗菌和抗病毒性能的概念验证研究
Elisa Passaglia,Beatrice Campanella,Serena Coiai et al.
Elisa Passaglia et al.
The European dependencies for raw materials supply from foreign countries have been unquestionably shown by COVID-19 outbreak and have become particular evident from the slow response to the need for high quality personal protective equipme...
COVID-19 into Chemical Science Perspective: Chemical Preventive Measures and Drug Development [0.03%]
从化学视角看新冠肺炎：化学防护措施和药物开发
Bimalendu Adhikari,Nihar Sahu
Bimalendu Adhikari
COVID-19 facts and literature are discussed into chemical science intuition highlighting the direct role of chemistry to the ongoing global pandemic by covering structural identification of the virus, chemical preventive measures and develo...
Facile Synthesis of Dihydroquinolines via Palladium Catalyzed Sequential Amination and Cyclisation of Morita-Baylis-Hillman Alcohols [0.03%]
钯催化Morita-Baylis-Hillman醇的串联胺化环化反应合成二氢异喹啉类化合物
Pambingal Rajan Sruthi,P Uma Sankar,Thachora Venu Saranya et al.
Pambingal Rajan Sruthi et al.
Quinolines and its derivatives are significant class of heterocyclic compounds which are identified as the key component in many natural products and biologically important molecules. We describe herein a facile method for the synthesis of ...
Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers [0.03%]
通过天然产物数据库筛选发现SARS-CoV-2刺突糖蛋白阻断剂的天然物质
Abdullah G Al-Sehemi,Fisayo A Olotu,Sanal Dev et al.
Abdullah G Al-Sehemi et al.
SARS-CoV-2 coronavirus has been recognized the causative agent of the recent and ongoing pandemic. Effective and specific antiviral agents or vaccines are still missing, despite a large plethora of compounds have been proposed and tested wo...
In Silico Identification of Potential Inhibitors of ADP-Ribose Phosphatase of SARS-CoV-2 nsP3 by Combining E-Pharmacophore- and Receptor-Based Virtual Screening of Database [0.03%]
通过结合E-药效团和基于受体的虚拟筛选来识别SARS-CoV-2 nsP3 ADP核糖基磷酸酶潜在抑制剂的计算方法研究
Pradip Debnath,Bimal Debnath,Samhita Bhaumik et al.
Pradip Debnath et al.
The recently emerged 2019 Novel Coronavirus (SARS-CoV-2) and associated COVID-19 disease cause serious or even fatal respiratory tract infection. Observing the spread, illness and death caused by COVID-19, the World Health Organization (WHO...
COVID-19: Emergence of Infectious Diseases, Nanotechnology Aspects, Challenges, and Future Perspectives [0.03%]
COVID-19：传染病的出现，纳米技术方面，挑战和未来展望
Akanksha Gupta,Sanjay Kumar,Ravinder Kumar et al.
Akanksha Gupta et al.
Wuhan, a city of China, is the epicenter for the pandemic outbreak of coronavirus disease-2019 (COVID-19). It has become a severe public health challenge to the world and established a public health emergency of international worry. This in...
Evaluation of the Inhibitory Activities of COVID-19 of Melaleuca cajuputi Oil Using Docking Simulation [0.03%]
穿心莲挥发油抑制新冠肺炎活性的分子对接模拟研究
Tran Thi Ai My,Huynh Thi Phuong Loan,Nguyen Thi Thanh Hai et al.
Tran Thi Ai My et al.
GC-MS was applied to identify 24 main substances in Melaleuca cajuputi essential oil (TA) extracted from fresh cajeput leaves through steam distilling. The inhibitory capability of active compounds in the TA from Thua Thien Hue, Vietnam ove...
Synthesis, Spectroscopic Characterizations of Novel Norcantharimides, Their ADME Properties and Docking Studies Against COVID-19 Mpr° [0.03%]
新型去胆烷-imide衍生物的合成与表征及其ADMET性质和Mpro酶抑制作用的研究
Hamdi Özkan,Şevki Adem
Hamdi Özkan
A series of novel Norcantharimide derivatives were synthesized and their structures were characterized by FTIR, 1H and 13C NMR spectroscopy as well as elemental analyses. The absorption, distribution, metabolism and excretion (ADME) propert...
Spiro-Indole-Coumarin Hybrids: Synthesis, ADME, DFT, NBO Studies and In Silico Screening through Molecular Docking on DNA G-Quadruplex [0.03%]
螺环吲哚香豆素杂环化合物：合成，ADME，DFT和NBO研究及通过分子对接的DNA G-四链体筛选研究
Leena Khanna,Sugandha Singhal,Subhash C Jain et al.
Leena Khanna et al.
New series of hybrids were synthesized by combination of 4-hydroxycoumarin with spiro[indol-indazole-thiazolidine]-diones and spiro[indol-pyrazole-thiazolidine]-diones, via hitherto unknown Schiff bases. The effects of substituents, such as...
Selective Inhibition of Enterovirus A Species Members' Reproduction by Furano[2, 3- d]pyrimidine Nucleosides Revealed by Antiviral Activity Profiling against (+)ssRNA Viruses [0.03%]
通过正链RNA病毒抗病毒谱分析发现法呢基（2,3-d）嘧啶核苷选择性抑制肠道病毒A族成员增殖
Liubov I Kozlovskaya,Anastasia D Golinets,Anastasia A Eletskaya et al.
Liubov I Kozlovskaya et al.
The rational design of broad-spectrum antivirals requires data on antiviral activity of compounds against multiple viruses, which are often not available. We have developed a panel of (+)ssRNA viruses composed of Enterovirus and Flavivirus ...