An updated radiosynthesis of [18F]AV1451 for tau PET imaging [0.03%]
一种更新的放射合成法用于tauPET成像的[18F]AV1451标记
Andrew V Mossine,Allen F Brooks,Bradford D Henderson et al.
Andrew V Mossine et al.
Background: [18F]AV1451 is a commonly used radiotracer for imaging tau deposits in Alzheimer's disease (AD) and related non-AD tauopathies. Existing radiosyntheses of [18F]AV1451 require complex purifications to provide d...
Clément Bailly,Caroline Bodet-Milin,Caroline Rousseau et al.
Clément Bailly et al.
Background: Oncological pretargeting has been implemented and tested in several different ways in preclinical models and clinical trials over more than 30 years. Despite highly promising results, pretargeting has not achi...
47Sc as useful β--emitter for the radiotheragnostic paradigm: a comparative study of feasible production routes [0.03%]
一项比较研究：生产反原型β-发射体SCm的可行性路线
Katharina A Domnanich,Cristina Müller,Martina Benešová et al.
Katharina A Domnanich et al.
Background: Radiotheragnostics makes use of the same molecular targeting vectors, labeled either with a diagnostic or therapeutic radionuclide, ideally of the same chemical element. The matched pair of scandium radionucli...
Evaluation of agonist and antagonist radioligands for somatostatin receptor imaging of breast cancer using positron emission tomography [0.03%]
用于乳腺癌生长抑素受体显像的阳性显像剂和阴性显像剂的评价：正电子发射断层扫描研究
Iulia Dude,Zhengxing Zhang,Julie Rousseau et al.
Iulia Dude et al.
Background: The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagoni...