Climate changes in the peritoneal cavity after CO2 laparoscopy: The risk of desertification [0.03%]
二氧化碳腹腔镜手术后盆腔的气候改变:沙漠化的风险
Wiebke Solass
Wiebke Solass
Single-port access for Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC): technique, feasibility and safety [0.03%]
单端口灌注式腹腔内化疗(PIPAC)的可行性与安全性研究
Marco Vaira,Manuela Robella,Alice Borsano et al.
Marco Vaira et al.
Background: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is a drug delivery system for treatment of peritoneal metastasis (PM). A limitation of this technique is the non-access rate (10-15 %) due to peritoneal...
Preoperative intraperitoneal oxaliplatin for unresectable peritoneal carcinomatosis of colorectal origin: a pilot study [0.03%]
术前腹腔内注射奥沙利铂治疗不可切除的结直肠癌来源的腹膜癌病:一项初步研究
Olivia Sgarbura,Emmanuelle Samalin,Sébastien Carrere et al.
Olivia Sgarbura et al.
Background: Peritoneal carcinomatosis in colorectal cancer is an advanced stage of the disease where improved survival can be attained whenever the resection associated with hyperthermic intreperitoneal chemotherapy is po...
Environmental safety during the administration of Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) [0.03%]
压力气雾化腹腔化疗(PIPAC)过程中的环境安全措施
Martin Graversen,Peter B Pedersen,Michael B Mortensen
Martin Graversen
Background: Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative technique for intraperitoneal drug delivery. This study investigates the efficacy of the occupational health safety measures taken to p...
Wiebke Solass,Florian Struller,Philipp Horvath et al.
Wiebke Solass et al.
The peritoneal cavity (cavum peritonei) is incompletely divided into spaces and recessus (or fossae), which are playing an important role in health and disease. Peritoneal subspaces are determined by the parietal attachments of the abdomina...
Pharmacokinetic problems in peritoneal drug administration: an update after 20 years [0.03%]
腹膜给药的药物动力学问题:20年后的最新研究进展
Michael F Flessner
Michael F Flessner
Intraperitoneal chemotherapy has demonstrated significant pharmacologic and clinical advantage over traditional intravenous administration for cancers that are restricted to the peritoneal cavity. The combination of cytoreductive surgery wi...
Randomized controlled trials evaluating cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in prevention and therapy of peritoneal metastasis: a systematic review [0.03%]
评估细胞减灭术(CRS)和腹腔内热灌注化疗(HIPEC)在预防和治疗腹膜转移的随机对照研究:系统综述
Clarisse Eveno,Marc Pocard
Clarisse Eveno
Background: Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is increasingly used to prevent or treat peritoneal metastases (PM) in selected indications. The objective of this ar...
Bidirectional chemotherapy in gastric cancer with peritoneal metastasis combining intravenous XELOX with intraperitoneal chemotherapy with low-dose cisplatin and Doxorubicin administered as a pressurized aerosol: an open-label, Phase-2 study (PIPAC-GA2) [0.03%]
联合静脉XELOX和腹腔内低温剂量顺铂、多柔比星压裂雾化吸入治疗胃癌伴腹膜转移的双向化疗:一项开放性II期研究(PIPAC-GA2)
Vladimir Khomyakov,Andrey Ryabov,Andrey Ivanov et al.
Vladimir Khomyakov et al.
Background: Peritoneal metastasis (PM) develop in more than 50 % of gastric cancer (GC) patients. Median survival without treatment is not more than 3-7 months, and 8-12 months after modern combination chemotherapy. Innovative therapeutic a...
Wiebke Solass,Philipp Horvath,Florian Struller et al.
Wiebke Solass et al.
The peritoneum consists of a layer of mesothelial cells on a connective tissue base which is perfused with circulatory and lymphatic vessels. Total effective blood flow to the human peritoneum is estimated between 60 and 100 mL/min, represe...