Textbook oncologic outcomes after cytoreductive surgery and HIPEC for colorectal peritoneal metastases: a single-centre cohort analysis [0.03%]
结直肠癌腹膜转移细胞减灭术及HIPEC术后肿瘤学结果的单中心队列分析
Niall Brindl,Arianna Castagna,Thilo Welsch et al.
Niall Brindl et al.
Objectives: Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is an established treatment for selected patients with colorectal peritoneal metastases (CPM). The recently proposed ...
Shear wave elastography to distinguish between hard and soft mucin in pseudomyxoma peritonei [0.03%]
剪切波弹性成像鉴别腹膜假黏液瘤中硬性和软性黏液
Carissa Vici,Nishka Tapaswi,Ashish Vaska et al.
Carissa Vici et al.
Objectives: Pseudomyxoma peritonei (PMP) is a rare peritoneal malignancy characterised by progressive accumulation of mucin within the abdomen. The gold standard of PMP treatment is cytoreductive surgery with hyperthermic...
PICCOS: study protocol for pressurised intraperitoneal aerosolised chemotherapy (PIPAC) in the management of cancers of the colon, ovary and stomach: a randomised controlled, phase II trial of efficacy in peritoneal metastases [0.03%]
PICCOS:腹腔压载式喷雾化疗(PIPAC)在结肠癌、卵巢癌和胃癌管理中的研究方案:一项关于腹膜转移病灶疗效的II期随机对照试验
Sadie E F Jones,Elena Brogden,Jamie Murphy et al.
Sadie E F Jones et al.
Objectives: Peritoneal metastases (PM) represent a significant unmet need requiring urgent development of treatment options to improve patient prognosis and quality of life (QoL). A novel anti-cancer technology is Pressur...
Malignant bowel obstruction related to advanced peritoneal metastases: survival outcomes of surgical treatment [0.03%]
与腹膜晚期转移相关的恶性肠梗阻:手术治疗的生存结果
Susanna Scarsi,Hugo Teixeira Farinha,Amaniel Kefleyesus et al.
Susanna Scarsi et al.
Objectives: Malignant bowel obstruction (MBO) caused by advanced peritoneal metastases (PM) carries a poor prognosis. Surgical intervention may be the only therapeutic option in selected cases, but operative risks must be...
Multicenter dose de-escalation phase I trial of pressurized intraperitoneal aerosolized chemotherapy (PIPAC) nab-paclitaxel and cisplatin in combination with systemic nab-paclitaxel in recurrent ovarian cancer patients: trial in progress [0.03%]
多中心减量剂量I期临床试验:在复发性卵巢癌患者中使用加压腹腔内喷雾化疗(PIPAC)联合系统性白蛋白结合型紫杉醇和顺铂的临床试验正在进行中
Vinita Popat,Paul H Frankel,Nora H Ruel et al.
Vinita Popat et al.
Objectives: Ovarian cancer (OC) often presents with peritoneal metastases (PM) which contribute significantly to morbidity and treatment resistance. Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) has emerged...
Preoperative chemotherapy in colorectal peritoneal metastatic disease - a real-world observational cohort study [0.03%]
结直肠癌腹膜转移的新辅助化疗:一项真实世界观察性队列研究
Peter H Cashin,Petter Frühling,Pontus Grönlund et al.
Peter H Cashin et al.
Objectives: The effects of preoperative chemotherapy have been poorly studied in colorectal cancer with peritoneal metastases (CRC-PM). This study evaluated preoperative chemotherapy from the first multi-disciplinary team...
The utility of a pleural carcinomatosis score for assessing resectability [0.03%]
评估肿瘤可切除性的胸膜癌负荷评分的实用性研究
Gabrielle Drevet,Yaniss Belaroussi,Valentin Soldea et al.
Gabrielle Drevet et al.
Objectives: Malignant pleural effusion is a common evolution of various cancers and is associated with poor prognosis and quality of life. Currently, the surgical approach is mainly palliative, involving videothoracoscopi...
Proposed strategy after complete LAMN (low-grade appendiceal mucinous neoplasm) resection by different RENAPE units: need for a new consensus? [0.03%]
RENAPE各单位行阑尾黏液性囊性肿瘤(LMN)切除术后的处理策略:需要新的共识吗?
Christian Mouawad,Abdelkader Taibi,Olivia Sgarbura et al.
Christian Mouawad et al.
Objectives: To evaluate current postoperative management strategies for incidentally discovered, completely resected low-grade appendiceal mucinous neoplasms (LAMNs) within the French RENAPE network and to assess the need...
High prevalence of KRAS and GNAS mutations in pseudomyxoma peritonei underscores opportunities for targeted therapeutic strategies [0.03%]
高KRAS和GNAS基因突变在假性粘液瘤腹膜种植中流行及其对靶向治疗策略的影响
Annette Torgunrud,Christin Lund-Andersen,Ben Davidson et al.
Annette Torgunrud et al.
Objectives: Pseudomyxoma peritonei (PMP) is a rare, slow-growing cancer with few efficacious treatment options in unresectable cases. Mutations in the KRAS and GNAS oncogenes are common, but the reported frequencies vary ...