Multicenter dose de-escalation phase I trial of pressurized intraperitoneal aerosolized chemotherapy (PIPAC) nab-paclitaxel and cisplatin in combination with systemic nab-paclitaxel in recurrent ovarian cancer patients: trial in progress [0.03%]
多中心减量剂量I期临床试验:在复发性卵巢癌患者中使用加压腹腔内喷雾化疗(PIPAC)联合系统性白蛋白结合型紫杉醇和顺铂的临床试验正在进行中
Vinita Popat,Paul H Frankel,Nora H Ruel et al.
Vinita Popat et al.
Objectives: Ovarian cancer (OC) often presents with peritoneal metastases (PM) which contribute significantly to morbidity and treatment resistance. Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) has emerged...
Preoperative chemotherapy in colorectal peritoneal metastatic disease - a real-world observational cohort study [0.03%]
结直肠癌腹膜转移的新辅助化疗:一项真实世界观察性队列研究
Peter H Cashin,Petter Frühling,Pontus Grönlund et al.
Peter H Cashin et al.
Objectives: The effects of preoperative chemotherapy have been poorly studied in colorectal cancer with peritoneal metastases (CRC-PM). This study evaluated preoperative chemotherapy from the first multi-disciplinary team...
The utility of a pleural carcinomatosis score for assessing resectability [0.03%]
评估肿瘤可切除性的胸膜癌负荷评分的实用性研究
Gabrielle Drevet,Yaniss Belaroussi,Valentin Soldea et al.
Gabrielle Drevet et al.
Objectives: Malignant pleural effusion is a common evolution of various cancers and is associated with poor prognosis and quality of life. Currently, the surgical approach is mainly palliative, involving videothoracoscopi...
Proposed strategy after complete LAMN (low-grade appendiceal mucinous neoplasm) resection by different RENAPE units: need for a new consensus? [0.03%]
RENAPE各单位行阑尾黏液性囊性肿瘤(LMN)切除术后的处理策略:需要新的共识吗?
Christian Mouawad,Abdelkader Taibi,Olivia Sgarbura et al.
Christian Mouawad et al.
Objectives: To evaluate current postoperative management strategies for incidentally discovered, completely resected low-grade appendiceal mucinous neoplasms (LAMNs) within the French RENAPE network and to assess the need...
High prevalence of KRAS and GNAS mutations in pseudomyxoma peritonei underscores opportunities for targeted therapeutic strategies [0.03%]
高KRAS和GNAS基因突变在假性粘液瘤腹膜种植中流行及其对靶向治疗策略的影响
Annette Torgunrud,Christin Lund-Andersen,Ben Davidson et al.
Annette Torgunrud et al.
Objectives: Pseudomyxoma peritonei (PMP) is a rare, slow-growing cancer with few efficacious treatment options in unresectable cases. Mutations in the KRAS and GNAS oncogenes are common, but the reported frequencies vary ...
Assessing data completeness in the international society for the study of pleura and peritoneum (ISSPP) PIPAC database: a multicenter evaluation from 2020-2024 [0.03%]
国际浆膜腔和腹膜研究学会(ISSPP)PIPAC数据库的数据完整性评估:2020年至2024年的多中心评价
Magnus Skov Jørgensen,Pernille Shjødt Hansen,Claus Wilki Fristrup et al.
Magnus Skov Jørgensen et al.
Objectives: In 2020, Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) reached stage 2b of the IDEAL framework and a prospective international PIPAC database was launched in June 2020 by the International Society f...
Adhesion obstacles effect on PIPAC patients with primary unresectable or recurrent platinum-resistant peritoneal metastasis from ovarian cancer [0.03%]
粘附障碍对卵巢癌原发不可切除或复发铂耐药性腹膜转移患者PIPAC的影响
Christos Iavazzo,Ioannis D Gkegkes
Christos Iavazzo
Comparison of clinical characteristics and outcomes between patients with complicated pleural infection caused by Streptococcus anginosus group and Klebsiella pneumoniae [0.03%]
由坏死性嗜血杆菌和肺炎克雷伯菌引起的继发性胸膜炎的临床特点及转归比较研究
Chang Ho Kim,Ji Eun Park,Sun Ha Choi et al.
Chang Ho Kim et al.
Objectives: Complicated pleural infections present significant challenges. Predominant causative microorganisms include the Streptococcus anginosus group (SAG) and Klebsiella pneumoniae (KP). However, limited data are ava...
The addition of collagenase to BromAc ® for the management of inoperable pseudomyxoma peritonei - in vitro results [0.03%]
BromAc®中添加胶原酶治疗不可手术的腹膜假黏液瘤的体外实验结果
Carissa Vici,Mathew Eapen,Pooja Narang et al.
Carissa Vici et al.
Objectives: Pseudomyxoma peritonei (PMP) is a rare peritoneal malignancy. BromAc ® is a novel therapeutic agent which has been developed to dissolve and facilitate the drainage of mucin as a palliative treatment for PMP;...
Advancements in nebulizers for pressurized intraperitoneal aerosol chemotherapy (PIPAC) [0.03%]
用于压腹给药化疗(PIPAC)的雾化器改进
Xiaosong Lin,Zifeng Yang,Yong Li
Xiaosong Lin
Introduction: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is an innovative intraperitoneal drug delivery technique utilizing a nebulizer to aerosolize liquid chemotherapy agents under pressure, distributing t...