Optimal drug delivery for intraperitoneal paclitaxel (PTX) in murine model [0.03%]
用于小鼠模型腹腔给药的最优药物递送以顺铂（PTX）为例
Joji Kitayama,Hironori Ishigami,Hironori Yamaguchi et al.
Joji Kitayama et al.
Background: Repeated intraperitoneal (IP) administration of paclitaxel (PTX) with concurrent systemic chemotherapy is clinically effective for the treatment of peritoneal metastases (PM) from gastric cancer. However, it i...
Normothermic intraperitoneal chemotherapy long term (NIPEC-LT) in the management of peritoneal surface malignancy, an overview [0.03%]
腹腔恶性肿瘤的大肠癌治疗：长期同温腹腔内化学疗法的概述
Paul H Sugarbaker
Paul H Sugarbaker
Background: Peritoneal metastases from gynecologic and gastrointestinal cancer is of increasing interest to surgical and medical oncologists because of newly recognized benefits of treatment. In contrast to prior outcomes...
Margo Steuperaert,Charlotte Debbaut,Patrick Segers et al.
Margo Steuperaert et al.
Despite a strong rationale for intraperitoneal (IP) chemotherapy, the actual use of the procedure is limited by the poor penetration depth of the drug into the tissue. Drug penetration into solid tumours is a complex mass transport process ...
Overview of the optimal perioperative intraperitoneal chemotherapy regimens used in current clinical practice [0.03%]
当前临床实践中最佳的围手术期腹腔内化疗方案概述
Kurt Van der Speeten,Lieselotte Lemoine,Paul Sugarbaker
Kurt Van der Speeten
Peritoneal surface malignancy (PSM) is a common manifestation of digestive and gynecologic malignancies alike. At present, patients with isolated PSM are treated with a combination therapy of cytoreductive surgery (CRS) and hyperthermic int...
Eelco de Bree,Dimosthenis Michelakis,Dimitris Stamatiou et al.
Eelco de Bree et al.
Intraperitoneal chemotherapy is associated with a significant pharmacokinetic and pharmacodynamic benefit and can, alone or in combination with systemic chemotherapy (bidirectional chemotherapy), be used for treating primary and secondary p...
Pharmacology of chemotherapy treatments for peritoneal metastases: optimizing and augmenting HIPEC [0.03%]
腹膜转移化疗药物学：优化和增强HIPEC疗法
Paul H Sugarbaker
Paul H Sugarbaker
A new ex vivo model for optimizing distribution of therapeutic aerosols: the (inverted) bovine urinary bladder [0.03%]
一种优化治疗性气溶胶分布的新型体外模型： inverted bovine urinary bladder)牛膀胱模型
Daniel Schnelle,Frank-Jürgen Weinreich,Janek Kibat et al.
Daniel Schnelle et al.
Background: Development of Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) requires adequate preclinical models. Methods: The ...
Lisa A Sheehan,Akash M Mehta,Saladin Sawan et al.
Lisa A Sheehan et al.
Background: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is the gold standard treatment for patients with pseudomyxoma peritonei (PMP) but involves routine bilateral salpingo-oophorec...
Changes in the coelomic microclimate during carbon dioxide laparoscopy: morphological and functional implications [0.03%]
二氧化碳腹腔镜手术中腹腔内微环境的变化：形态学与功能的影响
Robert B Wilson
Robert B Wilson
In this article the adverse effects of laparoscopic CO2 pneumoperitoneum and coelomic climate change, and their potential prevention by warmed, humidified carbon dioxide insufflation are reviewed. The use of pressurized cold, dry carbon dio...
Recommendations for pathological diagnosis on biopsy samples from peritoneal dialysis patients [0.03%]
腹膜透析患者的活检样本病理诊断建议
Kunio Kawanishi,Kazuho Honda,Chieko Hamada
Kunio Kawanishi
Peritoneal dialysis (PD) has been established as an essential renal replacement therapy for patients with end stage renal disease during the past half century. Histological evaluation of the peritoneal membrane has contributed to the pathop...