Intraperitoneal aerosolization of albumin-stabilized paclitaxel nanoparticles (Abraxane™) for peritoneal carcinomatosis - a phase I first-in-human study [0.03%]
人用第一阶段试验:用于腹膜癌栓的白蛋白稳定的紫杉醇纳米粒(Abraxane)的胸腔内雾化给药
Leen Van De Sande,Martin Graversen,Martin Hubner et al.
Leen Van De Sande et al.
Background: Nanoparticles hold considerable promise for aerosol-based intraperitoneal delivery in patients with carcinomatosis. Recently, results from preclinical and early clinical trials suggested that albumin-bound pac...
Treatment of peritoneal carcinomatosis with Pressurized IntraPeritoneal Aerosol Chemotherapy - PIPAC-OPC2 [0.03%]
使用Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)治疗腹膜癌(OPC2)
Martin Graversen,Sönke Detlefsen,Jon Asmussen et al.
Martin Graversen et al.
Background: Peritoneal carcinomatosis (PC) is a common endpoint in both gastrointestinal and non-gastrointestinal cancers, and PC is treated as other systemic metastases - unfortunately with disappointing results and cons...
Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in resected high-risk colon cancer patients - study protocol for the PIPAC-OPC3 Trial. A prospective, controlled phase 2 Study [0.03%]
用于高风险结肠癌患者的辅助经腹腔内喷雾化疗(PIPAC):PIPAOPC3试验研究方案。一项前瞻性、对照的II期研究
Martin Graversen,Sönke Detlefsen,Claus Fristrup et al.
Martin Graversen et al.
Background: Peritoneal metastasis (PM) is the second most common site of recurrence in colon cancer (CC) patients and accounts for approximately one-third of all recurrences. Patients with T4 or intraperitoneal perforated...
Role of laparoscopy in initial tumour staging in advanced epithelial ovarian cancer: A systematic review [0.03%]
腹腔镜在晚期上皮性卵巢癌初始肿瘤分期中的作用:系统综述
Natalia Zeff
Natalia Zeff
Background: The aim of this systematic review was to investigate the accuracy of additional staging laparoscopy (SL) in advanced epithelial ovarian cancer (AEOC) to predict futile laparotomy (FL). ...
Hypoxia, cytokines and stromal recruitment: parallels between pathophysiology of encapsulating peritoneal sclerosis, endometriosis and peritoneal metastasis [0.03%]
缺氧、细胞因子及间质募集:腹膜硬化、子宫内膜异位症和腹膜转移的病理生理学之间的相似性
Robert Beaumont Wilson
Robert Beaumont Wilson
Peritoneal response to various kinds of injury involves loss of peritoneal mesothelial cells (PMC), danger signalling, epithelial-mesenchymal transition and mesothelial-mesenchymal transition (MMT). Encapsulating peritoneal sclerosis (EPS),...
Therapeutic efficacy of systemic therapy for colorectal peritoneal carcinomatosis: Surgeon's perspective [0.03%]
腹膜转移的系统治疗之疗效:外科医生的观点
Jan Franko
Jan Franko
Treatment choices for colorectal peritoneal carcinomatosis/metastases include systemic therapy and increasingly cytoreductive surgery with intraperitoneal chemotherapy delivery. These options are best considered as complementary and not exc...
The concept of "Obstruction-Free Survival" as an outcome measure in advanced colorectal cancer management [0.03%]
"无妨碍生存"概念作为晚期结直肠癌管理的结局指标
Brendan J Moran,Alexios Tzivanakis
Brendan J Moran
Practice patterns, attitudes, and knowledge among physicians regarding cytoreductive surgery and HIPEC for patients with peritoneal metastases [0.03%]
关于细胞减灭术和HIPEC的实践模式、态度和知识——针对腹膜转移患者
Tyler Bernaiche,Erica Emery,Lana Bijelic
Tyler Bernaiche
Background: Cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) is a treatment option for patients with peritoneal metastases shown to provide improved overall survival for appropriately selected p...
(F)utility of computed tomography of the chest in the presence of pleural effusion [0.03%]
胸腔积液患者胸部计算机断层扫描的无用性
Tilak Pathak,Malvinder S Parmar
Tilak Pathak
Background: Pleural effusion is common and can cause significant morbidity. The chest X-ray is often the initial radiological test, but additional tests may be required to reduce uncertainty and to provide additional diag...
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in recurrent ovarian cancer with peritoneal metastasis: a prospective registry study on 41 patients [0.03%]
卵巢癌腹腔转移复发性肿瘤的减瘤手术和腹腔热灌注化疗:41例前瞻性登记研究
Melissa Ching Ching Teo,Claramae Shulyn Chia,Cindy Lim et al.
Melissa Ching Ching Teo et al.
Background: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastases from ovarian cancer have been shown to have a role in recurrent ovarian cancer, but are still not con...