Determinants of Hemodialysis Performance: Modeling Fluid and Solute Transport in Hollow-Fiber Dialyzers [0.03%]
血液透析性能决定因素:空心纤维透析器中溶质和流体运输的建模分析
Jian Yu,Vipul C Chitalia,Olukemi O Akintewe et al.
Jian Yu et al.
Hemodialysis constitutes the lifeline of patients with end stage renal disease, yet the parameters that affect hemodialyzer performance remain incompletely understood. We developed a computational model of mass transfer and solute transport...
Advancing cell instructive biomaterials through increased understanding of cell receptor spacing and material surface functionalization [0.03%]
通过提高对细胞受体间距和材料表面功能化的认识来推动细胞指令生物材料的发展
Stephanie A Maynard,Charles W Winter,Eoghan M Cunnane et al.
Stephanie A Maynard et al.
Regenerative medicine is aimed at restoring normal tissue function and can benefit from the application of tissue engineering and nano-therapeutics. In order for regenerative therapies to be effective, the spatiotemporal integration of tiss...
Holly Ryan,Daniel Bister,Sophia A Holliday et al.
Holly Ryan et al.
Purpose: The ancestral background of human cells may play a role in cells' behavior and response to therapeutic interventions in vitro. We investigate the prevalence of ancestry reporting in current biological research an...
Potential for Stem Cell-Based Therapy in the Road of Treatment for Neurological Disorders Secondary to COVID-19 [0.03%]
干细胞治疗在COVID-19继发神经系统疾病治疗中的应用潜力
Babak Arjmand,Peyvand Parhizkar Roudsari,Sepideh Alavi-Moghadam et al.
Babak Arjmand et al.
Abstract: The severe acute respiratory syndrome coronavirus 2 has led to the worldwide pandemic named coronavirus disease 2019 (COVID-19). It has caused a significant increase in the number of cases and mortalities since ...
Local delivery of FTY720 induces neutrophil activation through chemokine signaling in an oronasal fistula model [0.03%]
局部施用FTY720通过化学趋化信号在口鼻窦瘘模型中引起嗜中性粒细胞激活
A M Amanso,T C Turner,A Kamalakar et al.
A M Amanso et al.
Purpose: Cleft palate repair surgeries lack a regenerative reconstructive option and, in many cases, develop complications including oronasal fistula (ONF). Our group has developed a novel murine phenocopy of ONF to study...
Short interfering RNA (siRNA)-Based Therapeutics for Cartilage Diseases [0.03%]
用于软骨疾病的短干扰RNA(siRNA)治疗
Libo Zhou,Lee E Rubin,Chuanju Liu et al.
Libo Zhou et al.
Articular cartilage injury, as a hallmark of arthritic diseases, is difficult to repair and causes joint pain, stiffness, and loss of mobility. Over the years, the most significant problems for the drug-based treatment of arthritis have bee...
3D Printing: Advancement in Biogenerative Engineering to Combat Shortage of Organs and Bioapplicable Materials [0.03%]
三维打印:生物再生工程的进步以应对器官和生物适用材料短缺问题
Arpana Parihar,Vasundhara Pandita,Avinash Kumar et al.
Arpana Parihar et al.
Abstract: Organ or cell transplantation is medically evaluated for end-stage failure saving or extending the lives of thousands of patients who are suffering from organ failure disorders. The unavailability of adequate or...
Biocompatibility and Viscoelastic Properties of Injectable Resilin-Like Polypeptide and Hyaluronan Hybrid Hydrogels in Rabbit Vocal Folds [0.03%]
resilin-like肽和透明质酸混合水凝胶的生物相容性和流变学性质兔子声带中的研究
Renee E King,Hang Kuen Lau,Haiyan Zhang et al.
Renee E King et al.
Vocal fold scar, characterized by alterations in the lamina propria extracellular matrix, disrupts normal voice quality and function. Due to a lack of satisfactory clinical treatments, there is a need for tissue engineering strategies to re...
The Treatment of Muscle Atrophy after Rotator Cuff Tears Using Electroconductive Nanofibrous Matrices [0.03%]
导电纳米纤维基质在肩袖撕裂后肌肉萎缩治疗中的应用
Xiaoyan Tang,Nikoo Saveh Shemshaki,Varadraj N Vernekar et al.
Xiaoyan Tang et al.
Rotator cuff tears (RCTs) are a common cause of disability and pain in the adult population. Despite the successful repair of the torn tendon, the delay between the time of injury and time of repair can cause muscle atrophy. The goal of the...
Clinical Relevance of Pre-Existing and Treatment-Induced Anti-Poly(Ethylene Glycol) Antibodies [0.03%]
预存和治疗诱导的抗聚乙二醇化抗体的临床相关性
Helena Freire Haddad,Jacqueline A Burke,Evan A Scott et al.
Helena Freire Haddad et al.
Abstract: Poly(ethylene glycol) (PEG) is a nontoxic, hydrophilic polymer that is often covalently attached to proteins, drugs, tissues, or materials; a procedure commonly referred to as PEGylation. PEGylation improves sol...