Cerebrospinal fluid NPTX2/p-tau ratio as a biomarker for cognitive decline in neurodegenerative diseases [0.03%]
脑脊液NPTX2/p-tau比值作为神经退行性疾病认知衰退的生物标志物
Bárbara Fernandes Gomes,Mathias Sauer,Laia Montoliu-Gaya et al.
Bárbara Fernandes Gomes et al.
Introduction: Neuronal pentraxin 2 (NPTX2) and its use as a ratio with other synaptic proteins has emerged as a prognostic cerebrospinal fluid (CSF) biomarker across neurodegenerative diseases. ...
Heterogeneous trajectories of executive function in clinical Alzheimer's disease: Results from the 3C study [0.03%]
临床阿尔茨海默病患者执行功能异质性衰退模式：3C研究结果
Hélène Amieva,Maris Dussartre,Viviane Philipps et al.
Hélène Amieva et al.
Background: Alzheimer's disease (AD) shows considerable heterogeneity in cognitive decline. Executive function (EF), a core cognitive domain, may contribute to this heterogeneity and modulate AD progression. ...
Apathy and resting state functional connectivity across the Alzheimer's disease continuum [0.03%]
阿尔茨海默病谱系的好发症与静息态功能连接性之间的关系
Gladiliz Rivera-Delpín,Phebe Palmer,Maximilian M Ramseyer et al.
Gladiliz Rivera-Delpín et al.
Introduction: This study examined how apathy symptoms and awareness of those symptoms relate to resting-state functional connectivity magnetic resonance imaging (rs-fcMRI) across the Alzheimer's disease (AD) continuum usi...
Longitudinal sleep duration patterns and their association with cognitive decline in older Chinese adults [0.03%]
纵向睡眠时长模式及其与中国老年人认知能力下降的关联
Deqing Zeng,Wei Zhang,Yuqi Yang et al.
Deqing Zeng et al.
Introduction: Associations between sleep duration and cognitive decline are inconsistent, and the value of longitudinal changes versus static measurements remains unclear. ...
"Doctor, if it were you, which would you choose?": Navigating personal preference questions in anti-amyloid immunotherapy selection [0.03%]
“医生，如果是您，会选择哪个？”——在抗淀粉样蛋白免疫治疗选择中导航个人偏好问题
Eric Dinnerstein
Eric Dinnerstein
The approval of lecanemab and donanemab represents a watershed moment in Alzheimer Disease (AD) treatment, yet clinicians face a novel challenge: guiding patients through treatment selection when head-to-head comparative data are absent. Wh...
Prevalence of Lewy body pathology and phenotypic associations in patients with mild cognitive impairment: Evidence from the Interceptor study [0.03%]
轻度认知障碍患者路易体病理改变的患病率及表型关联：来自Interceptor研究组的证据
Simone Baiardi,Serena Caldera,Sabina Capellari et al.
Simone Baiardi et al.
Introduction: Clinical effects and prevalence of Lewy body (LB) pathology in patients with mild cognitive impairment (MCI) remain poorly understood. Metho...
Esther Lahoud,Frédéric Moynier,Brandon Mahan et al.
Esther Lahoud et al.
Introduction: Altered copper metabolism has been reported in Alzheimer's disease (AD), with post mortem brain tissue showing depletion of 65Cu compared with 63Cu. Whether such isotopic shifts can be detected in biofluids ...
Optimizing scalable approaches for early detection of cognitive impairment in primary care [0.03%]
优化初级保健中认知障碍早期检测的可扩展方法
Arthur H Owora,Diana Summanwar,Ambar Kulshreshtha et al.
Arthur H Owora et al.
Introduction: Unrecognized cognitive impairment remains common in primary care, delaying access to care. Methods: We conducted a prospe...
Community-based survey of perceived stigma in dementia: Insights from a collectivist culture [0.03%]
来自集体主义文化痴呆症感知污名的社区调查见解
Deniz Büyükgök,Sevde Nur Karabulut,Ata Onur Kepenek et al.
Deniz Büyükgök et al.
Introduction: In collectivist cultures, internalization of negative beliefs fosters stigma. This study aimed to assess the relationship between Alzheimer's disease (AD) knowledge and perceived stigma, focusing on sociodem...
Glymphatic clearance as revealed by diffusion tensor imaging along the perivascular space (DTI-ALPS) is associated with Alzheimer's disease neuropathology and periodic rsEEG alpha rhythms in mild cognitive impairment participants [0.03%]
沿血管周围空间的扩散张量成像（DTI-ALPS）揭示的胶质淋巴清除与轻度认知障碍患者的阿尔茨海默病神经病理学和周期性rsEEGα节律相关
Susanna Lopez,Claudio Del Percio,Roberta Lizio et al.
Susanna Lopez et al.
Introduction: We evaluated whether the brain glymphatic drainage function estimated by the diffusion tensor imaging along the perivascular space (DTI-ALPS) index relates to white matter (WM) integrity, Alzheimer's disease...