Clinical staging in Swedish primary care using the Amsterdam Instrumental Activities of Daily Living Questionnaire [0.03%]
采用阿姆斯特丹生活自理能力问卷评估瑞典初级保健中的临床分期问题
Ayesha Fawad,Sophie M van der Landen,Pontus Tideman et al.
Ayesha Fawad et al.
Introduction: We assessed the accuracy of the Amsterdam Instrumental Activities of Daily Living Questionnaire (A-IADL-Q) for clinical staging in Swedish primary care. ...
Ultra-processed food intake, cognitive function, and dementia risk: A cross-sectional study of middle-aged and older Australian adults [0.03%]
超加工食品摄入量、认知功能和痴呆风险:对中澳成年人的横断面研究
Barbara R Cardoso,Euridice Martinez Steele,Barbara Brayner et al.
Barbara R Cardoso et al.
Introduction: Ultra-processed food (UPF) consumption is linked to over 30 adverse health outcomes, including several risk factors for dementia such as cardiovascular disease, type 2 diabetes, and obesity. We aimed to exam...
Fixel-based analysis and free-water metrics in subjective cognitive decline and cognitive impairment no dementia [0.03%]
主观认知下降和非痴呆性认知障碍的固定点分析和自由水指标研究
Zheng Long Lee,Mervin Tee,Wei Ying Tan et al.
Zheng Long Lee et al.
Introduction: People with subjective cognitive decline (SCD) and cognitive impairment, no dementia (CIND) have higher risks of dementia. This study investigated whether fixel-based and free-water (FW) metrics, which exami...
Brain atrophy and clinical diagnosis independently predict default mode network failure across the Alzheimer's disease continuum [0.03%]
轻度认知功能障碍和阿尔茨海默病连续体中失败的默认模式网络的预测因素
Mohammed Alghamdi,Frederic von Wegner,Daniel Kam Yin Chan et al.
Mohammed Alghamdi et al.
Introduction: This study examined the link between default mode network (DMN) functional connectivity, cerebral small vessel disease (CSVD), brain atrophy, and plasma Alzheimer's disease (AD) biomarkers. ...
The relative contribution of modifiable and non-modifiable factors for determining cognition in mid-life individuals at risk for late-life Alzheimer's disease [0.03%]
决定中年时处于晚年患阿尔茨海默病风险人群的认知状况的可改变因素和不可改变因素的相对贡献
Bolin Cao,Qing Qi,Siobhan Hutchinson et al.
Bolin Cao et al.
Introduction: It remains unknown whether cognitive reserve contributors can protect against dementia from mid-life, in the context of several modifiable and non-modifiable risk factors, including family history and inheri...
From cognition to daily functioning: Insights from iatrogenic cerebral amyloid angiopathy [0.03%]
从认知到日常行为功能:医源性脑淀粉样血管病的见解
Giulia Marinoni,Benedetta Storti,Isabella Canavero et al.
Giulia Marinoni et al.
Introduction: Iatrogenic cerebral amyloid angiopathy (iCAA) is a rare form of cerebral amyloid angiopathy (CAA) caused by exposure to cadaveric dura mater grafts. Cognitive and health-related quality of life (HRQoL) outco...
Quantitative assessment of brain atrophy in bvFTD: Implications for diagnostic conversion [0.03%]
行为变异型额颞叶痴呆脑萎缩的量化评估及其诊断转化的影响
Chloe Beydoun,Halle Quang,Sophie Matis et al.
Chloe Beydoun et al.
Introduction: Brain atrophy increases diagnostic confidence in behavioral variant frontotemporal dementia (bvFTD); however, standardized tools have not been systematically applied. This study evaluated visual rating scale...
Multi-modal machine learning and gut microbiome pathway analysis for Alzheimer's risk prediction [0.03%]
多模态机器学习和肠道微生物组通路分析在阿尔茨海默病风险预测中的应用
Tallat Jabeen,Faezeh Karimi,Ali R Zomorrodi et al.
Tallat Jabeen et al.
Introduction: Early Alzheimer's disease (AD) risk assessment requires accessible alternatives to invasive biomarkers. We developed a multi-modal machine learning framework using questionnaire metadata from participants wi...
Associations of plasma phosphorylated tau217 with cognitive impairment and brain microstructural alterations in Alzheimer's disease [0.03%]
血浆磷酸化tau217与阿尔茨海默病认知障碍和脑微结构改变的关系
Miguel Ángel Rivas-Fernández,Sara Basanta-Torres,Mónica Lindín et al.
Miguel Ángel Rivas-Fernández et al.
Introduction: Plasma phosphorylated tau217 (p-tau217) is a promising biomarker for Alzheimer's disease (AD) risk detection. Its relationship with brain microstructure and cognitive impairment remains unclear. Multi-compon...
Plasma biomarker-informed brain topology for cognitive resilience: applications in non-pharmacological interventions concerning cognitive aging [0.03%]
基于血浆生物标志物的脑拓扑结构在认知韧性中的作用:非药物干预措施在认知衰老中的应用
Meishan Ai,Sa Zhou,Danni Li et al.
Meishan Ai et al.
Introduction: In the context of non-pharmacological interventions (NPIs), cognitive resilience refers to the capacity to enhance cognition from NPIs in the presence of neurodegeneration, and it is closely linked to brain ...