Subjective cognitive complaints and decline among aging individuals with prior repetitive head impact exposure [0.03%]
重复性脑震荡对老年人认知功能影响的横断面研究:主观认知下降者的纵向分析
Anna Aaronson,Monica T Ly,Yorghos Tripodis et al.
Anna Aaronson et al.
Introduction: Subjective cognitive complaints (SCC) can precede Alzheimer's disease and related dementias. SCC in the absence of objective impairment is termed subjective cognitive decline (SCD). This study aimed to chara...
The effect of treating hearing loss with hearing aids on plasma biomarkers of Alzheimer's disease and related dementias [0.03%]
听觉辅助装置治疗听力损失对阿尔茨海默病及相关痴呆血浆生物标志物的影响
Lachlan Cribb,Margarita Moreno-Betancur,Julia Sarant et al.
Lachlan Cribb et al.
Background: Though evidence indicates that treating hearing loss with hearing aids (HAs) could reduce dementia risk, the effects on biomarkers of Alzheimer's disease and related dementias (ADRD) remain unknown. ...
Identification of patients receiving amyloid-targeting therapies in observational studies using amyloid PET trajectories: Insights from LEADS [0.03%]
利用观察性研究中的淀粉样PET轨迹识别接受靶向淀粉样蛋白治疗的患者:来自LEADS的见解
Renaud La Joie,Ganna Blazhenets,Piyush Maiti et al.
Renaud La Joie et al.
Introduction: As amyloid-targeting therapies (ATTs) enter clinical care, observational cohorts must accurately ascertain ATT exposure. We developed an approach to flag mis/undocumented ATT in the Longitudinal Early-Onset ...
Regional amyloid PET asymmetry and long-term clinical trajectory in mild cognitive impairment [0.03%]
轻度认知障碍患者淀粉样PET侧别差异及长期临床病程的关系研究
Yunjin Lee,Sungwoo Kang,Yong Sung Kim et al.
Yunjin Lee et al.
Introduction: Hemispheric amyloid positron emission tomography (PET) asymmetry may capture prognostic information beyond binary amyloid status in amnestic mild cognitive impairment (aMCI). ...
Heritability of Alzheimer's disease-related plasma biomarkers in the Amish population [0.03%]
阿米什人群中的阿尔茨海默病相关血浆生物标志物的遗传性研究
Ping Wang,Yeunjoo E Song,Audrey Lynn et al.
Ping Wang et al.
Introduction: Plasma biomarkers for Alzheimer's disease (AD) hold promise for disease diagnosis and prediction, yet their genetic underpinnings remain under explored. ...
Features predicting data exclusion in imaging studies of Alzheimer's disease [0.03%]
阿尔茨海默病影像学研究中的数据剔除预测因素分析
Shaney Flores,Jalen Scott,Ruijin Lu et al.
Shaney Flores et al.
Introduction: Positron emission tomography (PET) without usable or accompanying magnetic resonance imaging (MRI) is typically excluded in quantitative analyses of Alzheimer's disease, potentially limiting study generaliza...
Exploring the spatial covariance of cerebral vascular density and amyloid burden in Alzheimer's disease [0.03%]
阿尔茨海默病患者脑血管密度和淀粉样蛋白负担的空间共变性研究
Lucia Argenti,Alessio Cirone,Federico Massa et al.
Lucia Argenti et al.
Introduction: Regional patterns of amyloid beta (Aβ) deposition in Alzheimer's disease (AD) may be influenced by cerebrovascular architecture. We examined the relationship between normative arterial and venous density ma...
Transient plasma p-tau217 elevations after electroconvulsive therapy: A two-case report [0.03%]
电休克治疗后瞬时的血浆p-tau217升高:两例报告
Henri Hokkanen,Emilia Hintsala,Jaakko Hotta et al.
Henri Hokkanen et al.
Introduction: Plasma phosphorylated tau (p-tau217) is increasingly used in the evaluation of Alzheimer's disease (AD). However, factors influencing its interpretation in real-world settings remain incompletely defined. ...
Impact of plasma pTau181 levels on clinician diagnostic confidence and management in memory and cognition clinics: A multi-site before-and-after study [0.03%]
血浆pTau181水平对记忆与认知门诊中临床诊断信心和管理的影响:一项多中心前后对照研究
Johannes C Michaelian,Azadeh Feizpour,James C Vickers et al.
Johannes C Michaelian et al.
Introduction: Recent advances allow blood tests to detect key proteins linked to Alzheimer's disease (AD). Methods: In this before-and-...
The prevalence and incidence of delirium superimposed on dementia in community settings: A systematic review and meta-analysis [0.03%]
社区环境中痴呆基础上的谵妄流行率和发病率的系统评价和荟萃分析
Alice Burnand,Elizabeth L Sampson,Kate Walters et al.
Alice Burnand et al.
Delirium superimposed on dementia (DSD) is a serious condition causing poor outcomes. There is a significant gap in understanding the epidemiology in community settings. This systematic review aimed to estimate the prevalence and incidence ...