Association of cancer with neuropathological markers of Alzheimer's disease and related dementias [0.03%]
阿尔茨海默病及相关痴呆症神经病理标志物与癌症的相关性
Stefan Teipel,Manas Akmatov,Bernhard Michalowsky et al.
Stefan Teipel et al.
Introduction: We assessed associations of cancer diagnoses with neuropathology of Alzheimer's disease (AD) and related dementias. Methods: ...
Correction to "Plasma lipid metabolites as biomarkers of early white matter degeneration in Alzheimer's disease" [0.03%]
关于“阿尔茨海默病白质退行性改变早期血浆脂质代谢产物生物标志物”的校正文章
[This corrects the article DOI: 10.1002/dad2.70217.]. © 2025 The Author(s). Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published...
Diagnostic utility of plasma p-tau217 differs by Alzheimer's disease tau-based subtypes [0.03%]
基于tau的亚型对血浆p-tau217诊断效用的影响不同
Seyed Hani Hojjati,Tracy A Butler,Seyed Javad Moosania Zare et al.
Seyed Hani Hojjati et al.
Introduction: Blood-based biomarkers, most notably plasma phosphorylated tau (p-tau)217, have transformed the diagnostic landscape of Alzheimer's disease (AD). ...
Toward targeted dementia prevention: Population attributable fractions and risk profiles in Germany [0.03%]
面向有针对性的痴呆症预防:德国的归因风险度和危险因素谱型
Iris Blotenberg,Jochen René Thyrian
Iris Blotenberg
Introduction: Effective dementia prevention requires understanding the distribution of modifiable risk factors and identifying high-risk subgroups. We estimated the prevention potential in Germany and identified risk prof...
Risk prediction of mild cognitive impairment using electronic health record data [0.03%]
基于电子健康记录数据的轻度认知障碍风险预测模型研究
Gang Li,Bryan Cobb,Todd M Nelson et al.
Gang Li et al.
Introduction: Mild cognitive impairment (MCI) is underdiagnosed by primary care providers (PCPs), with detection rates as low as 6%-15%. Predictive models support the identification of individuals at risk, enabling timely...
Plasma lipid metabolites as biomarkers of early white matter degeneration in Alzheimer's disease [0.03%]
血浆脂质代谢物作为阿尔茨海默病早期白质变性的生物标志物
Alireza Shaabanpoor Haghighi,Hamide Nasiri,Arman Ghayourvahdat et al.
Alireza Shaabanpoor Haghighi et al.
Introduction: Alzheimer's disease (AD) is characterized by progressive white matter (WM) degeneration. Circulating lipid metabolites may serve as early indicators of WM microstructural changes. In this study, we investiga...
Clinical performance of scalable automated p-tau 217 multi-analyte algorithmic blood test with reduced intermediate zone using multiplexed digital immunoassay [0.03%]
基于多重数字免疫测定的可扩展全自动p-tau 217 多分析物算法血液检测的临床性能及其减少的中间区间区段
David H Wilson,Karen Copeland,Mike Miller et al.
David H Wilson et al.
Introduction: To address an urgent need for a scalable, accurate blood test for brain amyloid pathology that provides a conclusive result for the greatest number of patients, we developed a multi-analyte algorithmic test ...
Profiles of blood-brain barrier and neurodegeneration markers in cerebrospinal fluid of patients with cerebral amyloid angiopathy [0.03%]
脑淀粉样血管病患者的脑脊液中血脑屏障和神经退行性标志物的特征分析
João Pinho,Arno Reich,Omid Nikoubashman et al.
João Pinho et al.
Introduction: There are few studies analyzing cerebrospinal fluid (CSF) in patients with cerebral amyloid angiopathy (CAA). Our goal was to compare blood-brain barrier and neurodegeneration markers in CSF in CAA patients ...
A lightweight machine learning tool for Alzheimer's disease prediction [0.03%]
一种轻量级的机器学习工具用于阿尔茨海默病预测
Vinay Suresh,Tulika Nahar,Arkansh Sharma et al.
Vinay Suresh et al.
Introduction: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that needs better predictive tools. Using the National Alzheimer's Coordinating Center Uniform Data Set, this study developed machine lear...
P-tau217 testing impact on intended management of patients presenting with cognitive impairment: A randomized clinical utility study [0.03%]
针对认知障碍患者的P- tau217检测对其预期治疗方案的影响:一项随机临床实用性研究
Samantha C Burnham,Haoyan Hu,Yifeng Tang et al.
Samantha C Burnham et al.
Introduction: Plasma biomarkers are minimally invasive tool for identifying Alzheimer's disease pathology. However, evaluation of their clinical utility remains limited. ...