Tumor lysis syndrome in advanced and high-grade endometrial cancers: A case report and review of the literature [0.03%]
晚期及高级别子宫内膜癌的肿瘤溶解综合征：一项病例报告和文献回顾
Johnathan Zhao,Heather Miller,Erin A Blake
Johnathan Zhao
•Tumor lysis syndrome is a rare but deadly complication of solid tumors.•We suggest that tumor lysis syndrome is especially deadly when it results from high grade or metastatic endometrial cancers.•Consider prophylactic measures to preve...
Can a symptom checklist improve the triage of patients following successful endometrial cancer treatment? [0.03%]
症状清单能改善子宫内膜癌治疗后患者的分诊吗？
Yang Peng,Monika Janda,Andreas Obermair
Yang Peng
Endometrial cancer (EC) is the fifth most common cancer in women in developed countries. Clinical practice guidelines recommend patients should be followed-up every 3-6 months after primary treatment of EC. Evidence suggests that 40% to 80%...
Liquid biopsy with droplet digital PCR targeted to specific mutations in plasma cell-free tumor DNA can detect ovarian cancer recurrence earlier than CA125 [0.03%]
通过特定突变液滴数字pcr的液体活检可早于ca125检测出卵巢癌复发
Takamichi Minato,Shin Ito,Bin Li et al.
Takamichi Minato et al.
Objective: Ovarian cancer (OC) is an intractable gynecological tumor, and frequent recurrence is experienced within a few years even after the complete eradication of tumor tissues by radical resection and neo-adjuvant ch...
Khalid El Bairi,Ouissam Al Jarroudi,Said Afqir
Khalid El Bairi
•Ovarian cancer seems is a neglected cancer in Morocco.•No publications that impact clinical practice were published in the last decade.•In this editorial, we provide our vision to develop this ignored area of gynecologic oncology. ...
Tumor BRCA testing can reveal a high tumor mutational burden related to POLE pathogenic variants [0.03%]
肿瘤BRCA检测可揭示与POLE致病突变相关的高肿瘤突变负担
M-C Villy,J Masliah-Planchon,S Melaabi et al.
M-C Villy et al.
Objective: Tumors harboring a POLE pathogenic variant, associated with high tumor mutational burden, are good candidates for immunotherapy. However, POLE pathogenic variants are not currently screened in routine clinical ...
The similarities and differences between mesonephric carcinoma and mesonephric-like carcinoma: Two cases [0.03%]
中肾癌和中肾样癌的相似与区别：两例分析
Amita Kulkarni,Adrian Chiem,Kamaljeet Singh et al.
Amita Kulkarni et al.
•Mesonephric carcinomas are rare cancers that arise from mesonephric remnants.•Mesonephric-like carcinomas are similar but with mesonephric differentiation.•These cases add to the limited literature of these separate but similar entities...
Uterine mesenchymal tumors harboring ALK fusions and response to ALK-targeted therapy [0.03%]
携带ALK融合的子宫间叶肿瘤及ALK靶向治疗反应
Chrisann Kyi,Claire F Friedman,Jennifer J Mueller et al.
Chrisann Kyi et al.
Inflammatory myofibroblastic tumor (IMT) of the uterus is a rare but aggressive malignancy that is often misdiagnosed. Approximately 50% of uterine IMTs (UMT) harbor rearrangements involving the ALK gene on chromosome 2p23 with subsequent o...
Discordant immunohistochemistry in an unusual MLH1 gene variant in a case of Lynch syndrome [0.03%]
利什曼病一个不寻常的MLH1基因变异的免疫组化检测不符现象病例报告
Prerana Nagabhushana,Snigdha Kumari,Minakshi Rohilla et al.
Prerana Nagabhushana et al.
Immunohistochemistry for mismatch repair proteins and microsatellite instability testing are recommended screening methods for Lynch syndrome. They have a good sensitivity and specificity, allowing for directed genetic testing and diagnosis...
Evaluation of the clinical Index of Stable febrile neutropenia risk stratification system for management of febrile neutropenia in gynecologic oncology patients [0.03%]
临床稳定型发热性中性粒细胞减少症风险分层系统的妇科肿瘤患者发热性中性粒细胞减少症管理价值评估
Karen A Monuszko,Benjamin Albright,Mary Katherine Montes De Oca et al.
Karen A Monuszko et al.
Objective: Scoring systems have been developed to identify low risk patients with febrile neutropenia (FN) who may be candidates for outpatient management. We sought to validate the predictive accuracy of the Clinical Ind...
Beryl L Manning-Geist,Dennis S Chi,Kara Long Roche et al.
Beryl L Manning-Geist et al.
Objective: We sought to describe the clinicopathologic features and outcomes of patients undergoing quaternary, quinary, or senary cytoreductive surgery for ovarian cancer. ...