R Shanoada,J Stephens,Z R Al-Wahab
R Shanoada
Background: Hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery has demonstrated survival benefits in advanced ovarian cancer. However, the safety of HIPEC administration in patients with...
Rescuing a refractory Leiomyosarcoma: ALK-DCTN1 fusion as a gateway to long-term control with Ceritinib [0.03%]
复发性平滑肌肉瘤的救治：ROS1-DCTN1融合阳性肉瘤使用塞瑞替尼治疗获得长期控制
Francis Yew Fu Tieng,Sri Kisha Subramaniam,Po Lin Ooi
Francis Yew Fu Tieng
Background: Uterine leiomyosarcoma (uLMS) is an aggressive malignancy with limited advanced-stage treatments. Actionable molecular alterations like ALK fusions are extremely rare but present critical opportunities for tar...
Primary ovarian synovial sarcoma in an adolescent mimicking a germ cell tumor: A case report and diagnostic challenge [0.03%]
青春期女孩卵巢滑膜肉瘤一例并向异质性生殖细胞肿瘤提出诊断挑战
Dyah Listyaningtyas,Hari Nugroho,Bagus Ngurah Brahmantara et al.
Dyah Listyaningtyas et al.
Background: Primary ovarian synovial sarcoma is an exceedingly rare malignancy that may mimic more common ovarian tumors, particularly in adolescents, posing significant diagnostic challenges. ...
Malignant transformation of mature ovarian teratoma into goblet cell adenocarcinoma: a case report [0.03%]
成熟卵巢畸胎瘤恶变为杯状细胞腺癌1例报告
Chinmayi Aryasomayajula,Nichole Legaspi,Mai Elzieny et al.
Chinmayi Aryasomayajula et al.
Background: Malignant transformation of ovarian mature cystic teratomas (MCTs) occurs in 0.17-2% of cases, with squamous cell carcinoma comprising over 80%. Transformation to goblet cell adenocarcinoma is exceedingly rare...
Quality of life and psychological outcomes with albumin-bound paclitaxel-carboplatin versus solvent-based paclitaxel-carboplatin as first-line chemotherapy in stage IC-IV ovarian carcinoma [0.03%]
与以白蛋白结合型紫杉醇-卡铂对比，以溶剂为基础的紫杉醇-卡铂作为一线化疗在卵巢癌IC-IV期中的生活质量及心理预后的差异研究
Nidhi Mahlawat,Atal Sood,Poorva Vias et al.
Nidhi Mahlawat et al.
Background: Declining psychological well-being and health-related quality of life represent an understudied burden in the treatment of ovarian cancer, caused by the disease and its chemotherapy. ...
Leading the way: A national mixed-methods survey of race, ethnicity, and gender among gynecologic oncology leaders at ACGME-accredited fellowship programs [0.03%]
先行一步：ACGME认证妇科肿瘤学领导力计划中关于种族、族裔和性别的全国混合方法调查研究
Jessica Velasquez,Caroline Gellman,Sara Wetzler et al.
Jessica Velasquez et al.
Objective: To describe self-reported demographics of gynecologic oncology leaders at U.S. institutions with an ACGME-accredited fellowship program, examine opinions regarding diversity and inclusion and perceived barriers...
A rare case of uterine carcinosarcoma presenting as complete uterine inversion: A case report [0.03%]
一例子宫癌肉瘤伴发完全性宫内翻的罕见病例报告
Olivia B Foy,Yingao Zhang,Julia Jahansooz et al.
Olivia B Foy et al.
Background: Uterine inversion is an uncommon phenomenon typically seen in the obstetric setting. Non-puerperal uterine inversion is even more rare and typically caused by benign pathology, though can be found in associati...
KAT6B/A::KANSL1 uterine sarcoma - A case with recurrences following uterine morcellation and the development of primary cell line model [0.03%]
KAT6B/A::KANSL1子宫肉瘤-一项关于子宫碎裂术后复发的病例及原发性细胞系模型建立的研究
Lauren Chen,Jiahui Liu,Isabelle Nechala et al.
Lauren Chen et al.
Background: KAT6B/A::KANSL1 uterine sarcoma has been recently recognized as a distinct type of uterine sarcoma displaying mixed endometrial stromal and smooth muscle features. ...
Preclinical in vitro and in vivo activity of trastuzumab deruxtecan against ERBB2-mutated cervical carcinomas with low HER2 expression [0.03%]
曲妥珠单抗deruxtecan对低HER2表达的ERBB2突变型宫颈癌的临床前体外和体内活性
Namrata Sethi,Sarah Ottum,Stefania Bellone et al.
Namrata Sethi et al.
Objective: Somatic HER2 mutations occur in up to 6% of cervical cancer patients and are associated with poor prognosis. We explored the activity of trastuzumab deruxtecan (T-DXd) as a novel targeted therapy against HER2-m...
Durable response to pembrolizumab plus axitinib in platinum-resistant ovarian clear cell carcinoma: A case report [0.03%]
帕博利珠单抗联合阿昔替尼治疗铂类耐药卵巢透明细胞癌的持久疗效：1例报告
Nikhil S Patel,Joshua J Cook,Danielle E Valcana et al.
Nikhil S Patel et al.
Introduction: Ovarian clear cell carcinoma (OCCC) is a rare and aggressive histologic subtype of epithelial ovarian cancer characterized by intrinsic chemoresistance and limited treatment options in the platinum-resistant...