Clinical characteristics and molecular epidemiology of KPC-NDM co-producing carbapenem-resistant Klebsiella pneumoniae in China: a multicentre retrospective case-control study [0.03%]
中国KPC-NDM双质粒碳青霉烯耐药肺炎克雷伯菌的临床特征和分子流行病学：多中心回顾性病例对照研究
Xi Li,Xinhong Han,Xinyan Tang et al.
Xi Li et al.
Background: KPC and NDM co-producing carbapenem-resistant Klebsiella pneumoniae (KN-CRKP) is an escalating global health threat with limited treatment options. ...
USP25 regulates atherosclerosis by restricting RIPK1-mediated inflammatory responses [0.03%]
USP25通过限制RIPK1介导的炎症反应调节动脉粥样硬化
Xian Su,Bincheng Zhou,Yanqi Xu et al.
Xian Su et al.
Background: Atherosclerosis is a common vascular disease that poses a serious threat to global health. However, the mechanism underlying the pathogenesis and progression of atherosclerosis remains elusive. ...
Improving overall child survival in conflict and fragile settings via integration of medical innovations into broader health system strengthening efforts: lessons from six rural hospitals in Somalia [0.03%]
索马里六家农村医院的经验教训：通过将医学创新整合到更广泛的卫生系统强化工作中来改善冲突和脆弱环境中的儿童整体生存状况
Yauba Saidu,Budzi Michael Ngenge,Igor Rudan
Yauba Saidu
R Hal Scofield
R Hal Scofield
Multidisciplinary international expert consensus recommendations on tissue acquisition in non-small cell lung cancer [0.03%]
非小细胞肺癌组织获取多学科国际专家共识推荐意见
Pyng Lee,Karim Abdelhamid,Rachel Butler et al.
Pyng Lee et al.
Background: The practice of precision medicine has transformed outcomes for patients with advanced non-small cell lung cancer (NSCLC). Precision medicine is increasingly applied to the therapeutic algorithms of early-stag...
The therapeutic effects of the VEGF decoy receptor fusion protein VEGF-Grab in chronic inflammatory diseases [0.03%]
VEGF-Grab融合蛋白在慢性炎症性疾病治疗中的效果研究
Youngeun Lee,Hee-Young Lee,Hye Seong Lim et al.
Youngeun Lee et al.
Background: Placental growth factor (PlGF) plays a crucial role in the pathogenesis of autoimmune diseases, including rheumatoid arthritis (RA) and multiple sclerosis (MS), by enhancing angiogenesis, disease-aggravating f...
5-Hydroxymethylcytosine profiles in circulating cell-free DNA serve as potential biomarkers for diagnosis and classification of adenomyosis [0.03%]
循环细胞游离DNA上5-羟甲基胞嘧啶图谱可作为诊断和分类子宫腺肌症的潜在生物标志物
Lei Zhang,Xiaotong Han,Xinran Gao et al.
Lei Zhang et al.
Background: Adenomyosis diagnosis and classification relies primarily on magnetic resonance imaging or pathological examination. Liquid biopsy has been widely applied in oncology but remains underexplored for adenomyosis....
Samuel Weissman,Ashley M Ginda,Alfonso Oceguera et al.
Samuel Weissman et al.
Background: The HIV reservoir was once considered to be transcriptionally silent. Evidence is emerging that a substantial portion of the reservoir is transcriptionally active. We explore the consequences of transcriptiona...
An ultrasensitive method for early detection of tuberculosis in asymptomatic high-risk individuals [0.03%]
高风险无症状个体结核病早期诊断的超灵敏方法
Evangeline Ann Daniel,Manohar Nesakumar,Hemalatha Haribabu et al.
Evangeline Ann Daniel et al.
Background: The dynamic spectrum of tuberculosis (TB) often results in underdiagnosis warranting the need for better diagnostics to accurately detect Mycobacterium tuberculosis (Mtb) in persons with asymptomatic, paucibac...
Sonya S Henry,Kevin E Duong,Tim Q Duong
Sonya S Henry
Background: SARS-CoV-2 infection could increase the long-term risk of recurrent chronic obstructive pulmonary disease (COPD) exacerbations. This study investigated the long-term risk of COPD exacerbations following SARS-C...