Detection of rabies virus RNA in dog-bite wounds in a rabies-endemic area: evidence from an observational cohort study [0.03%]
Carmen W E Embregts,Naseem Salahuddin,M Aftab Gohar et al.
Carmen W E Embregts et al.
Background: Rabies causes over 59,000 human deaths each year, primarily in endemic regions where surveillance is challenging. We report a prospective observational cohort study evaluating rabies virus (RABV) RNA detection...
Kristi Henjum,Bjørn Erik Neerland,Kaj Blennow et al.
Kristi Henjum et al.
Background: Alzheimer's disease (AD) is characterised by amyloid-beta (A) and tau (T) pathology, and neurodegeneration (N). AT(N) neuropathology precedes the symptomatic presentation of the disease. This asymptomatic phas...
Distinct metabolic signatures of Alzheimer's and Parkinson's disease revealed through genetic overlap [0.03%]
Sara E Stinson,Alexey A Shadrin,Zillur Rahman et al.
Sara E Stinson et al.
Background: Metabolic dysfunction is a major risk factor for neurodegeneration, yet the genetic architecture linking systemic metabolism to Alzheimer's disease (AD) and Parkinson's disease (PD) remains unclear. ...
eBioMedicine
eBioMedicine
Assessing the quality of AI-generated and physician-written discharge summaries: evaluation of an EHR-integrated tool in a Dutch academic hospital [0.03%]
Tarannom Mehri,Tun Nadalini,Anne H Hoekman et al.
Tarannom Mehri et al.
Background: Large language models (LLMs) offer potential to reduce administrative burden in clinical care by generating discharge summaries. Most prior evaluations have been limited to drafts, small cohorts, or non-integr...
irAE-GPT: leveraging large language models to identify immune-related adverse events in electronic health records and clinical trial datasets [0.03%]
Cosmin A Bejan,Michelle Wang,Sriram Venkateswaran et al.
Cosmin A Bejan et al.
Background: Large language models (LLMs) have emerged as transformative technologies, revolutionising natural language understanding and generation across various domains, including medicine. In this study, we investigate...
The AGPS regulatory variant rs113671272 confers esophageal squamous cell carcinoma susceptibility through allele-specific MEIS3 binding and NF-κB activation in Chinese populations [0.03%]
Xumeng Fang,Jiaying Deng,Ming Liu et al.
Xumeng Fang et al.
Background: Esophageal squamous cell carcinoma (ESCC) demonstrates pronounced ethnic disparities, being prevalent in Asian populations. However, the genetic mechanisms underlying this disparity remain poorly understood. T...
Molecular pathways driving clarithromycin benefit in community-acquired pneumonia: analysis of the ACCESS randomised trial [0.03%]
Emmanouil Stylianakis,Nikolaos Kakavoulis,Spyros Foutadakis et al.
Emmanouil Stylianakis et al.
Background: The double-blind randomised controlled ACCESS trial (ClinicalTrials.gov NCT04724044), conducted in hospitalised patients with community-acquired pneumonia (CAP), showed that the addition of clarithromycin to t...
Corrigendum to Overexpression of PIMREG promotes breast cancer aggressiveness via constitutive activation of NF-κB signaling EBioMedicine, Volume 43, (2019), Pages 188-200. doi: 10.1016/j.ebiom.2019.04.001 [0.03%]
Lili Jiang,Liangliang Ren,Xiaolan Zhang et al.
Lili Jiang et al.
Published Erratum
EBioMedicine. 2026 Apr 3:127:106186. DOI:10.1016/j.ebiom.2026.106186 2026
Interleukin-27 remodels the bone marrow niche to suppress B-cell development and leukaemia progression in mouse models [0.03%]
Jian-Min Zhu,Jing Xia,Kai-Ming Chen et al.
Jian-Min Zhu et al.
Background: Interleukin-27 (IL-27) is an immunoregulatory cytokine, but its role in B-cell haematopoiesis and B-cell acute lymphoblastic leukaemia (B-ALL) within the bone marrow (BM) niche remains unclear. ...