Effects of continuous exposure to low concentration of ClO2 gas on the growth, viability, and maintenance of undifferentiated MSCs in long-term cultures [0.03%]
低浓度二氧化氯持续暴露对长期培养的间充质干细胞增殖、存活及未分化维持的影响研究
Koushirou Sogawa,Ryoma Okawa,Kenji Yachiku et al.
Koushirou Sogawa et al.
Introduction: Hygienic management is more important in the manufacturing of cell products than in the production of chemical agents, because cell material and final product cannot be decontaminated. On the other hand, esp...
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein [0.03%]
基于黄芩素的体外研究：评估骨关节炎软骨细胞治疗后的抗炎活性
Chang-Chin Wu,Yi-Ru Chen,Dai-Hua Lu et al.
Chang-Chin Wu et al.
Introduction: Targeting inflammatory cascades is considered a promising way to prevent knee osteoarthritis (OA) progression. In terms of down-regulating the expression of inducible nitric oxide synthase (iNOS), interleuki...
Conversion of mesenchymal stem cells into a canine hepatocyte-like cells by Foxa1 and Hnf4a [0.03%]
Foxa1和Hnf4a诱导犬间充质干细胞向肝细胞分化研究
Suguru Nitta,Yuto Kusakari,Yoko Yamada et al.
Suguru Nitta et al.
Introduction: Hepatocytes, which account for the majority of liver tissue, are derived from the endoderm and become hepatocytes via differentiation of hepatic progenitor cells. Induced hepatocyte-like (iHep) cells and art...
Effect of cell seeding methods on the distribution of cells into the gelatin hydrogel nonwoven fabric [0.03%]
细胞播种方法对细胞在胶原海绵非织造布中分布的影响研究
Kumiko Matsuno,Toshiki Saotome,Naoki Shimada et al.
Kumiko Matsuno et al.
Therapeutic effects and adaptive limits of an acellular technique by ultrapurified alginate (UPAL) gel implantation in canine osteochondral defect models [0.03%]
超纯藻酸盐凝胶植入物治疗犬骨软骨缺损的疗效及适应性限度研究
Tomohiro Onodera,Rikiya Baba,Yasuhiko Kasahara et al.
Tomohiro Onodera et al.
Background: The aim of this study was to clarify the objective therapeutic effects of an acellular technique by ultrapurified alginate (UPAL) gel implantation in canine osteochondral defect models. ...
Advances in regenerative therapy: A review of the literature and future directions [0.03%]
再生医疗进展：文献综述与未来方向
Edward H Ntege,Hiroshi Sunami,Yusuke Shimizu
Edward H Ntege
There is enormous global anticipation for stem cell-based therapies that are safe and effective. Numerous pre-clinical studies present encouraging results on the therapeutic potential of different cell types including tissue derived stem ce...
Identification of neurospheres generated from human dental pulp stem cells in xeno-/serum-free conditions [0.03%]
无外源性血清条件下分离人牙髓干细胞球状体的鉴定研究
Yoko Kawase-Koga,Yasuyuki Fujii,Daiki Yamakawa et al.
Yoko Kawase-Koga et al.
Introduction: Cell-based therapies require an emerging alternative treatment using easily harvested cell sources. Neural stem cells derived from various tissues, including brain, bone marrow, skin and retina can give rise...
Thickness-wise growth technique for human articular chondrocytes to fabricate three-dimensional cartilage grafts [0.03%]
用于软骨细胞厚度方向生长的技术以制造三维软骨移植体技术
Tetsutaro Kikuchi,Tatsuya Shimizu
Tetsutaro Kikuchi
Introduction: Cutting the cost of manufacturing is important for extending the use of tissue-engineered therapeutic products. The present study aimed to develop a simple method for fabrication of cartilaginous tissues for...
miR-503/Apelin-12 mediates high glucose-induced microvascular endothelial cells injury via JNK and p38MAPK signaling pathway [0.03%]
高糖通过JNK和p38MAPK信号通路诱导微血管内皮细胞损伤的miR-503/ Apelin-12轴机制研究
Kai Chen,Xin-Lan Zhao,Lang-Bo Li et al.
Kai Chen et al.
Introduction: Diabetic patients are often accompanied by complications of diabetic vascular disease, which could lead to heart failure or stroke. In this work, we explored the role of miR-503/Apelin-12 in diabetic angiopa...
Adipose-derived stem cells improve tendon repair and prevent ectopic ossification in tendinopathy by inhibiting inflammation and inducing neovascularization in the early stage of tendon healing [0.03%]
脂肪源性干细胞通过抑制炎症和促进早期肌腱愈合中的新生血管形成来改善肌腱修复并预防肌腱病中异位骨化
Saeko Kokubu,Ryoko Inaki,Kazuto Hoshi et al.
Saeko Kokubu et al.
Introduction: Achilles tendinopathy is characterized by scar formation or ectopic ossification, both of which result in pain and worsened physical function in athletes and older people. Although cell therapy using adipose...