Bile duct reconstruction using scaffold-free tubular constructs created by Bio-3D printer [0.03%]
使用生物3D打印机创建的无支架管状结构进行胆道重建
Takashi Hamada,Anna Nakamura,Akihiko Soyama et al.
Takashi Hamada et al.
Introduction: Biliary strictures after bile duct injury or duct-to-duct biliary reconstruction are serious complications that markedly reduce patients' quality of life because their treatment involves periodic stent repla...
Dental pulp-derived stem cell-conditioned media attenuates secondary Sjögren's syndrome via suppression of inflammatory cytokines in the submandibular glands [0.03%]
牙髓源性干细胞条件培养基通过抑制下颌下腺炎症细胞因子来减轻继发性舍格伦综合征
Kenichi Ogata,Mayu Matsumura-Kawashima,Masafumi Moriyama et al.
Kenichi Ogata et al.
Introduction: Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease, which affects the exocrine glands. Its primary symptoms are decreased moisture in the mouth and eyes. Therapies are limited to treatment...
Norikatsu Miyoshi,Naotsugu Haraguchi,Tsunekazu Mizushima et al.
Norikatsu Miyoshi et al.
Although common cancer therapies, such as chemotherapy and radiation therapy, have recently improved and yielded good results, evaluated as tumor shrinkage, disease recurrence is still a common event for most cancer patients. This is termed...
Conflicting metabolic alterations in cancer stem cells and regulation by the stromal niche [0.03%]
癌症干细胞中的矛盾代谢变化及其由基质生态位的调节
Tadahito Yasuda,Takatsugu Ishimoto,Hideo Baba
Tadahito Yasuda
Recent studies have revealed that cancer stem cells (CSCs) undergo metabolic alterations that differentiate them from non-CSCs. Inhibition of specific metabolic pathways in CSCs has been conducted to eliminate the CSC population in many typ...
Kosuke Yoshida,Yusuke Yamamoto,Takahiro Ochiya
Kosuke Yoshida
Cancer stem cells (CSCs) are a small cell subpopulation in many cancer types and are involved in various processes of tumor progression, such as initiation, metastasis and recurrence. The distinguished features of CSCs include a variety of ...
Applications of 3D printed bone tissue engineering scaffolds in the stem cell field [0.03%]
基于干细胞的3D打印骨组织工程支架应用研究进展
Xin Su,Ting Wang,Shu Guo
Xin Su
Due to traffic accidents, injuries, burns, congenital malformations and other reasons, a large number of patients with tissue or organ defects need urgent treatment every year. The shortage of donors, graft rejection and other problems caus...
Low-temperature extrusion-based 3D printing of icariin-laden scaffolds for osteogenesis enrichment [0.03%]
用于骨生成增强的载伊卡瑞因低温挤出式3D打印支架
Jian-Ting Zhang,Shan-Shan Zhang,Chen-Guang Liu et al.
Jian-Ting Zhang et al.
Despite the accessibility to porous architectures through various biofabrication approaches for tissue engineering, incorporating various active growth regulators within their matrices that act as biochemical cues is also an essential attri...
Subcutaneous transplantation of engineered islet/adipose-derived mesenchymal stem cell sheets in diabetic pigs with total pancreatectomy [0.03%]
全胰切除糖尿病猪的工程化类胰腺组织/脂肪源性间充质干细胞片皮下移植研究
Mampei Yamashita,Toshiyuki Adachi,Tomohiko Adachi et al.
Mampei Yamashita et al.
Introduction: Intraportal islet transplantation is a promising therapeutic approach for patients with type 1 diabetes mellitus (T1DM). However, despite being minimally invasive, the method has some limitations, such as sh...
Development of a nasal mucosa-removal model for evaluating cell therapy [0.03%]
鼻粘膜去除模型的建立及其评价细胞治疗价值的研究
Shun Kikuchi,Tsunetaro Morino,Ryo Takagi et al.
Shun Kikuchi et al.
Introduction: Endoscopic sinus surgery is an effective surgical procedure for treating chronic sinusitis; however, extensive exposure of the bone in the nasal cavity can result in permanent disability postoperatively. Par...
Jun Takahashi
Jun Takahashi
Following intensive efforts since their discovery little more than 10 years ago, cell replacement therapy using induced pluripotent stem (iPS) cells is now becoming reality. However, there remain several obstacles in the translation of basi...