Safety and efficacy of bone marrow derived-mesenchymal stem cells transplantation in patients with amyotrophic lateral sclerosis [0.03%]
骨髓来源的间充质干细胞移植治疗肌萎缩侧索硬化症的安全性和有效性研究
Jalil Tavakol-Afshari,Amir Reza Boroumand,Najmeh Kaffash Farkhad et al.
Jalil Tavakol-Afshari et al.
Stem cell-based treatments have emerged as potentially effective approaches to delay the progression of amyotrophic lateral sclerosis (ALS). This study was designed as a single-center, prospective, and open-label study without a placebo con...
The protective mechanism of Klotho gene-modified bone marrow mesenchymal stem cells on acute kidney injury induced by rhabdomyolysis [0.03%]
骨化醇基因修饰的骨髓间充质干细胞对横纹肌溶解急性肾损伤保护机制的研究
WenHui Ni,Ying Zhang,Zhongcheng Yin
WenHui Ni
Background: Studies have shown that the Klotho gene has tremendous potential for future therapeutic purposes in both acute and chronic kidney diseases (CKD). This study aimed to investigate the possible protective mechani...
Asma Alanazi
Asma Alanazi
There is currently an ongoing coronavirus respiratory disease (COVID-19) pandemic that is caused by SARS-CoV-2 virus, which emerged out of Wuhan, China. In severe cases, the disease can progress to respiratory distress, hypoxia, and multi-o...
Laminin-511-derived recombinant fragment and Rho kinase inhibitor Y-27632 facilitate serial cultivation of keratinocytes differentiated from human embryonic stem cells [0.03%]
人胚胎干细胞分化角质细胞的串联培养被层粘连蛋白-511衍生的重组片段和Rho激酶抑制剂Y-27632促进
Ryo Takagi,Akiko Tanuma-Takahashi,Saeko Akiyama et al.
Ryo Takagi et al.
Introduction: Keratinocytes derived from pluripotent stem cells have a short proliferative lifespan under conventional culture conditions that are optimized for keratinocytes. Recently, a Rho kinase inhibitor, Y-27632, ha...
Combination therapy of Juzentaihoto and mesenchymal stem cells attenuates liver damage and regresses fibrosis in mice [0.03%]
Japanese herbal medicine菊池汤胜龙解毒方(Juzentaihoto)联合间充质干细胞减轻小鼠肝脏损伤和逆转肝纤维化
Takahiro Iwasawa,Shunsuke Nojiri,Atsunori Tsuchiya et al.
Takahiro Iwasawa et al.
Background: Liver cirrhosis is an end-stage multiple liver disease. Mesenchymal stem cells (MSCs) are an attractive cell source for reducing liver damage and regressing fibrosis; additional therapies accompanying MSCs can...
Goshi Shiota
Goshi Shiota
External administration of moon jellyfish collagen solution accelerates physiological wound healing and improves delayed wound closure in diabetic model mice [0.03%]
外用月亮水母胶原溶液可加速生理状态下伤口愈合并改善糖尿病小鼠模型的创面闭合延迟现象
Hideaki Sumiyoshi,Yosuke Okamura,Akira T Kawaguchi et al.
Hideaki Sumiyoshi et al.
Introduction: Artificial dermis is an effective therapeutic method for full-thickness dermal defects. However, the currently available artificial dermis made of porcine or bovine type I collagen has several limitations su...
Cultured epithelial autografts for the treatment of large-to-giant congenital melanocytic nevus in 31 patients [0.03%]
自体培养上皮细胞移植治疗31例大片型先天性巨痣
Naoki Morimoto,Toshihito Mitsui,Yasuhiro Katayama et al.
Naoki Morimoto et al.
Introduction: Giant congenital melanocytic nevus (GCMN) is a large melanocytic nevus, and its full-thickness removal is usually difficult due to the lack of skin available for reconstruction. Curettage is an alternative a...
Biodistribution studies for cell therapy products: Current status and issues [0.03%]
细胞治疗产品药代分布研究：现状与问题点分析
Yoshiteru Kamiyama,Yoichi Naritomi,Yuu Moriya et al.
Yoshiteru Kamiyama et al.
Information on the biodistribution (BD) of cell therapy products (CTPs) is essential for prediction and assessment of their efficacy and toxicity profiles in non-clinical and clinical studies. To conduct BD studies, it is necessary to under...